Such important data and so exciting that a CID was written by a med student first author 👏
FungalDoc AKA Andrej Spec
@fungaldoc.bsky.social
ID at @washuID obsessed with fungal infections. Section Chief, Transplant ID. #fungus #TxID #IDTwitter Head of @WU_Mycoses. Deputy Editor-OFID. He/Him
This is a really exciting study for me for two reasons. 1. Led by a medical student!! 2. It helps us understand that the change in antigen concentrations is at least in part related to immune status. Suggesting that it correlates with disease activity.
Using data from a Midwest referral center, we found that chronic non-HIV immunosuppression was associated with more persistent antigenuria and slower antigen clearance than in immunocompetent patients and immune-reconstituted PLWH. pubmed.ncbi.nlm.nih.gov/42700964/ @fungaldoc.bsky.social
This is a really exciting study for me for two reasons. 1. Led by a medical student!! 2. It helps us understand that the change in antigen concentrations is at least in part related to immune status. Suggesting that it correlates with disease activity.
Using data from a Midwest referral center, we found that chronic non-HIV immunosuppression was associated with more persistent antigenuria and slower antigen clearance than in immunocompetent patients and immune-reconstituted PLWH. pubmed.ncbi.nlm.nih.gov/42700964/ @fungaldoc.bsky.social
Using data from a Midwest referral center, we found that chronic non-HIV immunosuppression was associated with more persistent antigenuria and slower antigen clearance than in immunocompetent patients and immune-reconstituted PLWH. pubmed.ncbi.nlm.nih.gov/42700964/ @fungaldoc.bsky.social
Histoplasma Capsulatum Antigen Persistence and Rate of Decay During Treatment of Histoplasmosis Varies by Immune Status - PubMed
Patients with chronic non-HIV immunosuppression demonstrated persistent antigenuria and cleared antigen more slowly compared to immunocompetent patients and immune reconstituted PLWH. Given the association of antigen persistence with immune status, its clinical significance in non-HIV immunocompromi …
pubmed.ncbi.nlm.nih.gov
This was a new one for me at today’s NE ID Conference: Emerging fungal infection in turtles/tortoises called Emydomyces testavorans One treatment option is terbinafine baths The more you know… @germhuntermd.bsky.social @fungaldoc.bsky.social
A really important step. DOOR is the future of mycology. In a field where meds and treatments are "heroic", the outcomes are more nuances than just dead or alive.
🍄🧫Check out our latest work on implementing DOOR approach in medical mycology trials. academic.oup.com/cid/advance-... @drluiso.bsky.social @fungaldoc.bsky.social
A really important step. DOOR is the future of mycology. In a field where meds and treatments are "heroic", the outcomes are more nuances than just dead or alive.
🍄🧫Check out our latest work on implementing DOOR approach in medical mycology trials. academic.oup.com/cid/advance-... @drluiso.bsky.social @fungaldoc.bsky.social
🍄🧫Check out our latest work on implementing DOOR approach in medical mycology trials. academic.oup.com/cid/advance-... @drluiso.bsky.social @fungaldoc.bsky.social
Reanalyzing a Randomized Controlled Trial of Invasive Aspergillosis Using a Desirability of Outcome Ranking Approach: Voriconazole Versus Amphotericin B Deoxycholate
Abstract. Efficacy of antifungal therapy in invasive aspergillosis relies primarily on mortality, overlooking critical measures of treatment response. We u
academic.oup.com
We are looking to recruit transplant ID faculty. Happy to support different career types. WashU Medicine Division of Infectious Diseases is seeking a full-time transplant infectious diseases clinician. facultyopportunities.wustl.edu/Posting/Deta...
Opportunity Details - Faculty Opportunities
facultyopportunities.wustl.edu
We are looking to recruit transplant ID faculty. Happy to support different career types. WashU Medicine Division of Infectious Diseases is seeking a full-time transplant infectious diseases clinician. facultyopportunities.wustl.edu/Posting/Deta...
Opportunity Details - Faculty Opportunities
facultyopportunities.wustl.edu
Evidence from an Indonesian island points to the successful elimination of lymphatic filariasis. Watch @washumedicine.bsky.social Dr. Peter U. Fischer, PhD, and Senior Scientist Kerstin Fischer as they discover their work's long-term impact: source.washu.edu/2026/03/a-we...
A welcome instance of hope
Evidence from a small island in Indonesia points to the successful elimination of a parasitic worm that causes a devastating tropical disease.
source.washu.edu
Hello #IDWeek2025! Warm up for #IDBugBowl with this little question... Hope you do better than me! #IDSky @fungaldoc.bsky.social
This was my experience too. There is a paper out there, where I analyzed the data, wrote the methods, and much of the results, setting the tone for what the story of the paper will be. I then went to another institution, and the paper was published without my knowledge, and without my name.
"The day the paper was published should have been a moment of pride. Instead, it felt like a quiet erasure." #ScienceWorkingLife https://scim.ag/4p3eH5g
This is such an interesting study. Many times in medicine we feel that something should be a risk factor for death. But it turns out not to be. And often, even when that data is clearly presented, people still continue to not believe it. Negative studies teach us often more than a positive study.
🚨🍄In a cohort of patients with Candida BSI, LVAD presence was not associated with increased 30-day or 90-day mortality.Despite higher acuity, LVAD support did not independently worsen short-term outcomes in Candida BSI. @fungaldoc.bsky.social academic.oup.com/ofid/advance... @ofidjournal.bsky.social
This is such an interesting study. Many times in medicine we feel that something should be a risk factor for death. But it turns out not to be. And often, even when that data is clearly presented, people still continue to not believe it. Negative studies teach us often more than a positive study.
🚨🍄In a cohort of patients with Candida BSI, LVAD presence was not associated with increased 30-day or 90-day mortality.Despite higher acuity, LVAD support did not independently worsen short-term outcomes in Candida BSI. @fungaldoc.bsky.social academic.oup.com/ofid/advance... @ofidjournal.bsky.social
🚨🍄In a cohort of patients with Candida BSI, LVAD presence was not associated with increased 30-day or 90-day mortality.Despite higher acuity, LVAD support did not independently worsen short-term outcomes in Candida BSI. @fungaldoc.bsky.social academic.oup.com/ofid/advance... @ofidjournal.bsky.social
Comparative outcomes following Candida bloodstream infection in patients with left ventricular assist devices
AbstractBackground. Candida bloodstream infections (BSI) carry a high risk of adverse outcomes. Left ventricular assist devices (LVAD) are increasingly use
academic.oup.com
www.journalofinfection.com/article/S016... 🚨🚨🍄🍄 new research from Washington University Mycoses Group (WUMG) reveals that Invasive aspergillosis & mucormycosis show broad geographic distribution across the U.S. Regions with higher incidence report lower associated mortality. @fungaldoc.bsky.social
Geographic distribution and associated mortality of invasive aspergillosis and mucormycosis among Medicare enrollees in the United States (2008-2015)
Invasive aspergillosis and mucormycosis are widely distributed in the United States, with certain regions experiencing significantly higher incidences. For invasive aspergillosis, each increase of 5 c...
journalofinfection.com
Enjoyed listening to @fungaldoc.bsky.social on The Curbsiders this week! Love hearing more about the dimorphics! #IDSky thecurbsiders.com/curbsiders-p...
#495 Fungal Infections -Histo/Blasto/Cocci with Dr. Andrej Spec - The Curbsiders
Transcript available via YouTube Why we need to stop calling them “endemic” mycoses & more fungi fun! Feeling muddled about endemic mycoses? We tackle the clinical presentation of diseases like histop...
thecurbsiders.com
We are recruiting for a new faculty member in the Transplant ID section at @WashUMedID. Highly dynamic section, with immense growth potential. We want to help people build a career in patient care, education or research. facultyopportunities.wustl.edu/Posting/Deta...
Opportunity Details - Faculty Opportunities
facultyopportunities.wustl.edu
We are recruiting for a new faculty member in the Transplant ID section at @WashUMedID. Highly dynamic section, with immense growth potential. We want to help people build a career in patient care, education or research. facultyopportunities.wustl.edu/Posting/Deta...
Opportunity Details - Faculty Opportunities
facultyopportunities.wustl.edu
We are recruiting Transplant ID physicians into a vibrant and diverse group with active research and patient care expertise. We are looking for physicians who excel in patient care and are interested in developing an academic career through research, education or excellence in patient care!
You can now buy both of our new books for 25% off using the code ID25. You can buy the other ID books too. www.us.elsevierhealth.com/comprehensiv... www.us.elsevierhealth.com/comprehensiv...
Comprehensive Review of Infectious Diseases - 9780323881852
With complete coverage of the most frequently encountered concepts and conditions in infectious disease, Comprehensive Review of Infectious Diseases, Second Edition, is perfect for board review or qui...
us.elsevierhealth.com
You can now buy both of our new books for 25% off using the code ID25. You can buy the other ID books too. www.us.elsevierhealth.com/comprehensiv... www.us.elsevierhealth.com/comprehensiv...
Comprehensive Review of Infectious Diseases - 9780323881852
With complete coverage of the most frequently encountered concepts and conditions in infectious disease, Comprehensive Review of Infectious Diseases, Second Edition, is perfect for board review or qui...
us.elsevierhealth.com
I wanted to share the preface from our upcoming second edition of our book, The Comprehensive Review of Infectious Disease. This has been in my head for years. Glad to finally see it in the printed word.
Cannot agree more with @germhuntermd.bsky.social @fungaldoc.bsky.social @natebahrid.bsky.social "Better awareness, diagnostic testing practices, and reporting are needed to improve patient outcomes and enhance our understanding of coccidioidomycosis epidemiology" jamanetwork.com/journals/jam...
Estimated Burden of Coccidioidomycosis
This cross-sectional study generates a systematic and rigorous estimate of national incident symptomatic coccidioidomycosis cases by developing a model to account for cases missed through national sur...
jamanetwork.com
Looking forward to it! Loved the first edition and will recommend this next one to our fellows!
I wanted to share the preface from our upcoming second edition of our book, The Comprehensive Review of Infectious Disease. This has been in my head for years. Glad to finally see it in the printed word.
I used the first edition for boards. Very excited there will be an updated version!
This edition will also have a separate book of board style questions that you can use to study for your boards! www.amazon.com/Comprehensiv...
Comprehensive Self-Assessment in Infectious Disease: Questions and Answers
Comprehensive Self-Assessment in Infectious Disease: Questions and Answers [Spec MD MSCI, Andrej, Escota MD, Gerome, Davies MBBS MD MSc FRCPath MRCP FHEA PG Cert MedEd, Bethany, O’Halloran MB BCh BAO PhD, Jane] on Amazon.com. *FREE* shipping on qualifying offers. Comprehensive Self-Assessment in Infectious Disease: Questions and Answers
amazon.com