Our abstract this week comes from Chantal Fayad who is researching the role of FGF signalling in hypochondroplasia and ageing at @institutimagine.bsky.social with Prof Laurence Legeai-Mallet. Please contact Chantal if you'd like to know more! www.linkedin.com/in/chantal-f... #MSCA_DN #FGF #ageing

This week's abstract is by Matteo Signor who is studying the link between the ageing autonomic nervous system and IVD degeneration, supervised by @zsuzsajenei-lanzl.bsky.social at @goetheuni.bsky.social. Send Matteo a message to find out more! www.linkedin.com/in/matteo-si... #IVD #ageing #MSCA_DN

Our next @change-ecm.bsky.social abstract is by Giulio Gatto, a PhD candidate from @goetheuni.bsky.social. Giulio is investigating OA-associated changes in cartilage ECM under the supervision of @fzaucke.bsky.social. Please message Giulio if you'd like to know more. www.linkedin.com/in/giulio-ga...

Fantastic line-up of speakers! If you are interested in matrix research, please come to Heidelberg🤗

DGMB@matrixbiologie.bsky.social · 11mo ago

While we update our website regarding #DGMB2026, you can find a list of confirmed speakers here! 👇 We are so happy to have them and already look forward to lots of exciting science! #ECRs, we'll have a pre-meeting together with the #EU-CHANGE network - more info coming soon! #ECM #MatrixBiology

The final version of our recent review on challenges in the development of DMOADs is available here👍 #osteaorthritis rdcu.be/eAflJ

Rijuta Lamba, Alexandra Naba @nabalabuic.bsky.social, @valerioizzi.bsky.social and team present MatriCom, a single-cell RNA-sequencing data mining tool to infer cell–ECM interactions. Highlight: journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/... #OpenAccess

Great meeting! Hope to see many of you there👇

DGMB@matrixbiologie.bsky.social · last yr.

📣SAVE THE DATE! #DGMB2026 will be held 15th-17th April 2026 in beautiful Heidelberg! More details to follow soon! We will also have a satellite meeting for #EarlyCareerResearchers before the main meeting, giving you a chance to meet other #ECRs and make new conference-friends! #matrixbiology

🚨 1 Milliarde Euro würde fehlen – was bedeutet das für Forschung & Lehre an hessischen #Hochschulen? Unser Präsident Prof. Dr. Enrico Schleiff findet klare Worte zum aktuellen Entwurf des Hochschulpakts. Jetzt ansehen und teilen! #Hochschulpakt #GoetheUni #Hessen

Please have a look at this recent review on #osteoarthritis. Thanks to Mario Rothbauer and the entire team for letting me contribute! rdcu.be/epH7q

Excited to share our latest work on a novel mutation in a gene that causes non-classical OI👇 url:https://academic.oup.com/jbmrplus/article/doi/10.1093/jbmrpl/ziaf083/8128480

Please have a look at and enjoy reading the latest publication I have contributed to😉

Nature Reviews Rheumatology@natrevrheum.nature.com · last yr.

New content online:

Now, the same group (including myself😉) presents data on how other cartilage biomarkers are changed as a result of immobilization. Immobilization by 21-days of bed rest causes changes in biomarkers of ... www.sciencedirect.com/science/arti...

Immobilization by 21-days of bed rest causes changes in biomarkers of cartilage homeostasis in healthy individuals

To investigate the effects of 21 days bed rest immobilization (with and without exercise and nutrition intervention) on serum concentrations of cartil…

sciencedirect.com

In 2024, the effect of immobilization (by a 21 day bed rest) on the degradation of collagen II was published in the journal Osteoarthritis and Cartilage by Liphardt et al. Immobilization by 21 days of bed rest results in type II collagen degr... www.sciencedirect.com/science/arti...

Immobilization by 21 days of bed rest results in type II collagen degradation in healthy individuals

To investigate the effects of 21 days of bed rest immobilization (with and without exercise and nutrition interventions) on type II collagen biomarker…

sciencedirect.com

Honoured to be invited to such a fantastic meeting!

I'll be there👇😉

Orthopaedic Research Society@orssociety.bsky.social · 2y ago

You’re invited to one of the most anticipated events of #ORS2025, the JOR Editorial Recognition Dinner and Networking Reception. Join us for an evening of celebration, networking, and fun. Registration required. Learn more and register now: bit.ly/4g9rwGd

Are you attending the annual meeting of the Orthopaedic Research Society #ORS2025 meeting in Phoenix? If so👇

With the following link authors.elsevier.com/c/1kPnD3Im5h... you have free access (for 50 days) to a recent study that our lab contributed to. We thank the lead authors for involving in this exciting project.

Amazing study!👇

Geert Carmeliet@geertlab.bsky.social · 2y ago

Big congratulations to Shauni Loopmans for her excellent PhD research, now online in @natmetabolism.bsky.social. This study reveals that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival rdcu.be/d5Q65 (1/3)

In case you are interested in the role of the #ECM in inherited skeletal disorders other than #osteogenesis imperfecta like e.g. #Marfan or #Ehlers-Danlos, #achondroplasia, #ciliopathies: watch out for this book that will be published soon (January 2025)!

🚨publication alert🚨 Open Access! Please have a look at our latest review: doi.org/10.1515/jpem...

Osteogenesis imperfecta: shifting paradigms in pathophysiology and care in children

The formation of functional bone requires a delicate interplay between osteogenesis and osteolysis. Disturbances in this subtle balance result in an increased risk for fractures. Besides its mechanica...

doi.org

Spectacular view of #Cologne yesterday evening

A very dark bluesky yesterday evening in Frankfurt

A more detailled summary of my research interests/activities....generated here: scholargoggler.com

My first post on bsky☺️ The link to our review on #osteoarthritis recently published in Osteoarthritis and Cartilage www.oarsijournal.com/article/S106...

Osteoarthritis year in review 2024: Biology

Osteoarthritis (OA) research is a fast-growing and extremely wide field, in which a substantial increase in knowledge has been achieved over the last year. It covers many different topics, however, a ...

oarsijournal.com