@gbadegesinlab.bsky.social
Pediatric Kidney Doc, Kidney Genomics, Physician Scientist & Associate Dean for Physician Scientist Development @DukeMedSchool.bsky.social Harnessing genomic tools to uncover safe, effective & durable therapies for nephrotic syndrome
Excited to share the link to our new paper in KI. A big step towards predicting therapy response in Peds nephrotic syndrome at 1st presentation @asnkidney.bsky.social @kdigo.org @kidneyint.bsky.social Huge global collaborative efforts nam11.safelinks.protection.outlook.com?url=https%3A... 🙏🏽
Very impt piece of work on precise diagnosis of APOL1 mediated kid dxs. Patients with N264K (M1) co-inherited with G2 may have other kidney dxs and not AMKD. Huge implications for use of emerging AMKD therapy and interpretation of CT. Congratulations @genetickidneydoc.bsky.social and collaborators🎉
Simone Sanna-Cherchi 🧬@genetickidneydoc.bsky.social · 5mo agoOnline today on @jamanetworkopen.com our new paper on the role of #APOL1 M1 in increasing precision diagnosis for CKD in individuals from African ancestry. Collaboration with @kidneyomicsamps.bsky.social @gbadegesinlab.bsky.social @kirylukk.bsky.social et al jamanetwork.com/journals/jam...
It was a pleasure reviewing the @kdigo.org 2025 clin practice guidelines for PD NS for US practice. Thanks @ajkd.bsky.social for asking me to do this with Chia-shi Wang. Highlight, Levamisole not approved for use in Humans in the US!!👍
American Journal of Kidney Diseases@ajkd.bsky.social · 6mo agoKDOQI US Commentary on the KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children by Chia-shi Wang and Rasheed Gbadegesin bit.ly/4q9yAqo (FREE)
Thank you @opeyemiolabisi.bsky.social and the whole @dukekidney.bsky.social , @gbadegesinlab.bsky.social , Laura Barisoni et al! It was a great couple of days of scientific excellence mixed with pleasant company and nice weather. #APOL1 #FSGS #rFSGS #genetics #pediatrics #NephSky #SkyNeph #Medsky
Opeyemi Olabisi@opeyemiolabisi.bsky.social · 12mo agoIt was a pleasure to have Dr. Sanna-Cherchi @genetickidneydoc.bsky.social give an excellent, well-attended, Renal Grand Rounds at @dukekidney.bsky.social He is an embodiment of collaborative excellence💪🏾 @columbiakidney.bsky.social
We have the momentum, let’s solve the problems of rFSGS, first step is to have critical mass of patients’ derived biomaterials to start answering fundamental questions that will lead us to better understanding of disease mechanisms and durable therapy🙏🏽
Simone Sanna-Cherchi 🧬@genetickidneydoc.bsky.social · last yr.Our #rFSGS biobank is growing and we welcome patients from all over the world! Please reach out to us if you are a patient or a physician caring for one. We are creating a resource for everyone to use with the goal of resolving this disease and find new cures. #KidneyMonth2025 #RareDisease #genetics
Happy to share this excellent editorial on our recent NEJM paper www.nejm.org/doi/10.1056/... by Simone @genetickidneydoc.bsky.social Simone you nailed it! www.nejm.org/doi/10.1056/... 🙏🏽
APOL1 Kidney Disease Variants — Information from West Africa at Last | NEJM
Chronic kidney disease (CKD) has a devastating effect on populations of African ancestry worldwide and disproportionately affects persons in West African countries,1 in whom CKD, once present, ofte...
nejm.org
Our initial observations in @dukepump.bsky.social a program addressing the workforce crisis in uronephrology. journals.lww.com/cjasn/fullte... Take home: program is feasible, student feelings of id as BioMed researcher up!! We are excited with these baby steps #NIDDK @asnkidney.bsky.social #ASPN 👏
Addressing the Workforce Crisis in Uronephrology: Design... : Clinical Journal of the American Society of Nephrology
An abstract is unavailable.
journals.lww.com
Happynew year College Students!! We are accepting applications for tthe Duke PUMP. A summer research and immersion program to address the workforce crisis and diversify the workforce in Uronephrology. Spend & enjoy a summer of science at Duke. Link for application duke.qualtrics.com/jfe/form/SV_...
Just saw this paper which says that APOL1 channel activity drives podocyte injury, and that small molecule APOL1 inhibitors are beneficial in a mouse model of APOL1-mediated CKD...intriguing: www.nature.com/articles/s41...
Small molecule APOL1 inhibitors as a precision medicine approach for APOL1-mediated kidney disease - Nature Communications
Apolipoprotein L1 genetic variants contribute to a subtype of proteinuric kidney disease referred to as APOL1-mediated kidney disease (AMKD). Here the authors report the discovery and characterization...
nature.com
Welcome @dukepump.bsky.social
Duke Paired Undergraduate Mentoring Program in Uronephrology@dukepump.bsky.social · 2y agoPlease welcome Duke PUMP to Bluesky. This is a summer research program set up to address workforce crisis in uronephrology @dukeopsd.bsky.social @opeyemiolabisi.bsky.social @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social #NIDDK #ASPN @dukectsi.bsky.social
Duke PUMP is our effort to address the workforce crisis in Nephrology& urology. We are accepting applications for our 3rd cohort. Only 37% of positions filled in Peds Neph this year!! We should engage young folks in career in Neph from elementary school!! #NIDDK #ASPN @asnkidney.bsky.social
Duke OPSD PRIME@duke-opsd-prime.bsky.social · 2y agoOPSD PRIME PUMP exposes #Undergraduates to #Laboratory #Research and career paths for #PhysicianScientists @dukemedschool.bsky.social @gbadegesinlab.bsky.social We promote health equity by developing #Diverse cohorts. Apply by February 24th, 2025. Learn more: medschool.duke.edu/research/res...
Amazing, the story of the humble beginning of Congressman Shri Thanedar of Michigan @shrithanedar.bsky.social The only Pharmaceutics researcher in Congress. In him we have a huge champion for #rFSGS @rfsgsinitiative.bsky.social @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social
Great meeting!! Tough problem(s) requiring great minds and stakeholders with “can do attitude”. Amazing listening to Congresswoman Haley Stevens of Michigan linking biomedical research and workforce development to National defense!! @rfsgsinitiative.bsky.social
Matt Sampson@kidneyomicsamps.bsky.social · 2y agoThe epitome of a Physician-Scientist. @gbadegesinlab.bsky.social swoops in to DC this morning from being on call last night in North Carolina to moderate an early session here at @rfsgsinitiative.bsky.social
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky 1. The importance of stupidity in scientific research Open Access journals.biologists.com/jcs/article/...
Match day!! Huge workforce crisis in Peds Nephrology, only 20% of program filled second to the last overall. We need urgent intervention #ASPN #NIDDK #AAP #ASN @atomickidney.bsky.social @jostflynnmd.bsky.social @asouth-neph.bsky.social @kidneyomicsamps.bsky.social @rheaultm.bsky.social
Writing a scientific article: A step-by-step guide for beginners Main sections that an average article should contain; the elements that should appear in these sections, and some pointers for making the overall result attractive and acceptable for publication. www.sciencedirect.com/science/arti...
How to write a good scientific review article. #PhD #scisky #medsky Open Access febs.onlinelibrary.wiley.com/doi/10.1111/...
Bluesky community, please welcome @dukeopsd.bsky.social This is an innovative centralized PSTP program @dukemedschool.bsky.social It leverage & extend access to research & career support for Trainees & Young Investigators. Please follow us🙏🏽
Nephrology and Transplant community please welcome Krista @kristalentine.bsky.social to bsky @kidneyomicsamps.bsky.social @rfsgsinitiative.bsky.social @rheaultm.bsky.social @nephrosparks.bsky.social @mcstarr1.bsky.social @atomickidney.bsky.social @mannonmom.bsky.social
@gbadegesinlab.bsky.social · 2y agoHello bsky community of biomedical researchers, nephrologists, transplant nephrologists, Please welcome and follow @kristalentine.bsky.social giant and thought leader in transplant research, #APOLLO @the-asci.bsky.social @asnkidney.bsky.social @opeyemiolabisi.bsky.social 🙏🏽
Hello bsky community of biomedical researchers, nephrologists, transplant nephrologists, Please welcome and follow @kristalentine.bsky.social giant and thought leader in transplant research, #APOLLO @the-asci.bsky.social @asnkidney.bsky.social @opeyemiolabisi.bsky.social 🙏🏽
🚨 We are officially two weeks out from the #rFSGSConference! 🚨 Reserve your spot so you can join us in Washington, DC to discuss #rFSGS research, funding, and treatments. Register today: www.scgcorp.com/rFSGS2024/Re...
rFSGS is a major cause of kidney tx loss in FSGS. Join us on Dec 9th in DC with pts and other major stakeholders in the room to discuss how we can harness modern tools to address this area of need @kidneyomicsamps.bsky.social @genetickidneydoc.bsky.social #alessiafornoni @opeyemiolabisi.bsky.social
rFSGS Initiative@rfsgsinitiative.bsky.social · 2y agoThe Recurrent Focal Segmental Glomerulosclerosis (#rFSGS) Conference is on Dec. 9 in Washington, DC! The #rFSGSConference program is led by groundbreaking researchers in the field & designed for patients & advocates, to learn from & connect with one another! Register: www.scgcorp.com/rFSGS2024/Re...
Check out the final version of this paper in AJT focusing on genetic evaluation of kidney transplant candidates. www.sciencedirect.com/science/arti... Thanks Christie Thomas #UniIowa for leading the efforts and all the Co-Authors.
Evaluation for genetic disease in kidney transplant candidates: A practice resource
The increasing availability of clinically approved genetic tests for kidney disease has spurred the growth in the use of these tests in kidney transpl…
sciencedirect.com
@altmetric.com please add @bsky.social mention to your journal article metrics. All researchers especially biomedical researchers, love this❤️ to send the message loud and clear. @opeyemiolabisi.bsky.social @genetickidneydoc.bsky.social @kidneydoc101.bsky.social
Ethylene glycol intoxication presents w/ anion gap metabolic acidosis & acute oxalate tubulopathy. Detection of urinary calcium oxalate monohydrate crystals helps in diagnosis [not classic dumbbell nor envelope shaped (dihydrate) but rather “cigar” shaped]. Slide courtesy of @jrseltzer.bsky.social
@altmetric.com please add @bsky.app mention to your journal article metrics. All researchers especially biomedical researchers, love this❤️ to send the message loud and clear. @opeyemiolabisi.bsky.social @genetickidneydoc.bsky.social @kidneydoc101.bsky.social
www.bostonglobe.com/2024/11/22/l... this may be behind a paywall, but worth sharing nonetheless. Thankfully, most people don’t have experience with talking to parents who have lost a child. The tips the author shares at the end are very helpful if anyone faces this tough situation.
Here we go my pubmed goggler @scholargoggler.bsky.social Cool app. Thanks @bsky.app This is the home for all Scholars and highly functioning folks👍
