Excited for the ASPET Annual Meeting next week! The Blythe Lab will be presenting three posters -- stop by to meet the team and see what we've been working on.

Happy to share the published version of this work from my time at Stanford! Here, we leverage mathematical modeling and a large dataset of growth rates, cell sizes, and proteomics to probe how E. coli coregulate their geometry and their macromolecular composition. doi.org/10.1038/s414...

Happy to have this out there! I had a lot of fun working with (and learning from) @akshitg.bsky.social on this mini-review on microdiversity in microbial populations and how current ecological theory fails to quantitatively explain the observations. doi.org/10.1111/1462...

Paradox of the Sub‐Plankton: Plausible Mechanisms and Open Problems Underlying Strain‐Level Diversity in Microbial Communities

“Paradox of the sub-plankton: Plausible mechanisms and open problems underlying strain-level diversity in microbial communities” by Akshit Goyal* and Griffin Chure*. This work highlights the limitati...

doi.org

Excited to finally share this work w/ @suryaganguli.bsky.social Tl;dr: we find the first closed-form analytical theory that replicates the outputs of the very simplest diffusion models, with median pixel wise r^2 values of 90%+. arxiv.org/abs/2412.20292

Generate random draws from a Cauchy just to remind yourself that you almost never actually want a Cauchy anywhere in a probabilistic model.

Rafe Meager (they/them)@economeager.bsky.social · 2y ago

generate random draws from a cauchy just to feel something

Happy to have this out today in JOSS! Hplc-py is a Python software tool that quantitatively decomposes complex chromatograms into their constituent signals: joss.theoj.org/papers/10.21...

hplc-py: A Python Utility For Rapid Quantification of Complex Chemical Chromatograms

Chure et al., (2024). hplc-py: A Python Utility For Rapid Quantification of Complex Chemical Chromatograms. Journal of Open Source Software, 9(94), 6270, https://doi.org/10.21105/joss.06270

joss.theoj.org

I am cautiously optimistic that my lab will have an open postdoc position in 2024. If you are potentially interested, please reach out. Or if you know somebody who might be interested, please connect us. My email is on our lab website sklab.science

Over the past two years, I've used HPLC to measure carbon turnover in microbes. The most painful part was quantifying the resulting chromatograms. Today, I (with Jonas Cremer) released hplc-py: A python tool that makes quantification easy. cremerlab.github.io/hplc-py

If you’re interested in comprehensive guidance for improving your communication skills I cannot recommend the book “Trees, Maps, and Theorems” enough, www.principiae.be/X0100.php. 2/5