Harms 😈 and benefits 👼 of Pancreatic Cyst Surveillance Guidelines - 3 guidelines compared @amergastroassn.bsky.social @gastroenterology.bsky.social 👉 Overall Harm-to-benefit ratio disappointing 👈 ✋ STOP surveillance in stable cysts not harm www.sciencedirect.com/science/arti...

Amazing international team at the #Wirsung2026 Pancreas Conference in @hpdsurgery.bsky.social Padova Great minds - great connections - true friendship 🇮🇹🇳🇱🇯🇵🇰🇷 @marcbesselink.bsky.social

🔵 Post pancreatectomy mortality: the new seminal paper from ISGPS 👉 occurring within 90 days from pancreatectomy linked to it through root-cause analysis 3️⃣ categories ✂️ vascular complexity 💦 pancreas specific 🫀 C/P sudden journals.lww.com/annalsofsurg... @marcbesselink.bsky.social

Celiac axis stenosis 🕵️‍♀️ the unknown risk factors for additional morbidity after a pancreatoduodenectomy 🌵 CAS incidence 16% in 1.7k cases published in Annals of Surgery 🚨 Grade B/C associated bile leak, liver perfusion failure, gastric ischemia journals.lww.com/annalsofsurg...

New paper! Long Term Metabolic Outcomes Following Pancreatectomy and Autologous Islet Transplantation: Systematic Review and Meta-Analysis ⤵️⤵️⤵️ onlinelibrary.wiley.com/doi/10.1002/...

Long Term Metabolic Outcomes Following Pancreatectomy and Autologous Islet Transplantation: Systematic Review and Meta‐Analysis

This systematic review and meta-analysis assessed long-term outcomes following total pancreatectomy with islet autotransplantation (TPIAT). Seventeen studies including 1332 patients were analyzed. Th...

onlinelibrary.wiley.com

✂️ Does venous resection affect the delivery of adjuvant chemoterapy? 🇮🇹 🇨🇳 280 resected veins / 68% ISGPS type 3 💉 70% received adjuvant chemo prolonging survival ✋ Disclaimer: authors favors neoadj chemo, conceptually always! link.springer.com/article/10.1...

Minimally Invasive 🤜 🤛 Open Pancreatoduodenectomy for Resectable Neoplasms @nejm.org @marcbesselink.bsky.social 🔴🔴 🏥 RCT 288 pts / 14 centers 🤖 Conversion 8% but ⤵️ time to functional recovery, POPF, SSI 🤝 MI not inferior (in expert hands - in both cases…) evidence.nejm.org/doi/full/10....

💦 Use and management of drains in pancreas surgery remains controversial 🔎 MA of 17 RCT - 4k patients out now in @bjsopen.bsky.social 🏆 Whipple level 1a: selective early drain removal 🏆 Left panc: no drain policy 🎖️ Do you stick to highest level of evidence?! 🫵 academic.oup.com/bjsopen/arti...

A great honor to serve as faculty for the course in advanced pancreas surgery at @umeauniversitet.bsky.social 🇸🇪 led by @asifhalimi.bsky.social 🫶 An amazing experience to learn and exchange knowledge on an evolving / crucial issue!

What is your anticoagulation practice 💉 after portal vein resection in pancreas surgery ?! 🧑‍🧑‍🧒‍🧒 1k pts / 90 days thrombosis 7% in Annals of Surgery 🔮 Predictors resection type / graft material 🩸 Therapeutic anticoagulation 📉 early thrombosis but 👎 at 90 days journals.lww.com/annalsofsurg...

It’s out!!! 🔥🔥🔥 The PREOPANC-2 is in @thelancet.com Neoadjuvant FOLFIRINOX 🤜🤛 Gemcitabine based chemoradiotherapy in resecatble / BR ⚖️ No difference in overall survival 😰 Serious adverse events 40% 👍 Both regimens may be considered www.thelancet.com/pdfs/journal...

Pancreas2000 is the official postgraduate course of the EPC @myueg.bsky.social Aimed at fostering the new generation of pancreatologists… almost 2 years with 5 in person meetings! #science #passion #education and #pancreas 🫵 Join us! Applications open in October

Amazing #Yellowstone National Park 🏞️

⏰ Early onset of GI cancers ⛑️ a window for prompt diagnosis / therapy @bjsurgery.bsky.social ☝️Incidence in <50 y/o rising particularly in 🚺 🧬 Germline mutations but most sporadic 🚬 Modifiable factors smoke/alcohol/diet 🔬 Multidisciplinarity + research needed academic.oup.com/bjs/article/...

Early-onset gastrointestinal cancers: comprehensive review and future directions

The incidence of early-onset gastrointestinal cancers—commonly defined as being diagnosed in patients <50 years of age—is rising at an alarming rate glo

academic.oup.com

Non-pancreatic neoplasms in and around the 🪷 ampulla of Vater: International Guidelines 🔬 Optimal pathology assessment 🤝 Multidisciplinary pathways leading to best treatment 🔜 Future research line have been defined in @myueg.bsky.social journal! onlinelibrary.wiley.com/doi/10.1002/ue…

🟣🟣 Liver Transplantation For Colorectal Cancer Liver Metastases: does sex matter?! ♐️ Post LT recurrence liver > F; 🫁 only in M 🔮 Survival predicted by CEA, 👉 sided CRC, tumor size, 🧬 KRAS mutation 🔑 Selection criteria key factor www.jhep-reports.eu/article/S258... @jhepatology.bsky.social

What to do when recurrent acute pancreatitis 🤕 is the only worrisome feature of a BD-IPMN 🍇?! Even more tricky in case of comorbidities like liver fibrosis … ⚖️ where do you set your threshold for surgery?! 🧐

What is "Conversion surgery" 🐛➡️🦋 for upfront unresectable upper GI and HPB cancers ⁉️ 💉 Triggered by improvements in non surgical therapies 🧰 Many techniques included 🏆 Able to improve survival! 💡 All u need to know ⬇ comprehensive review in @bjsopen.bsky.social academic.oup.com/bjsopen/arti...

Is it possible to attend 4️⃣ LAPC cases simultaneously?! 🙈 only at University Hospital Heidelberg (UKHD) 🇩🇪!!! A unique team led by Christoph Michalski paving the way to treat pancreas cancer in a modern fashion, taking into account biology 🧬 and “extreme” surgery 🪡

Out now in @sages.org journal! POPF 🐳 after distal pancreatectomy still a poorly understood complication 🙃 🌍 International validation of the fistula risk score 800 pts 🧯POPF predicted by BMI, NAT, robot approach 🤔 FRS insufficient discrimination 🧐 !!! link.springer.com/article/10.1...

So honored to be part of this!!! 👇🎓💪

Marc Besselink@marcbesselink.bsky.social · last yr.

#Horaest 🎓 @AnoukEmmen today 🙌 “Improving outcomes in minimally invasive #pancreatoduodenectomy” incl the #DIPLOMA2 RCT. @abuhilal.bsky.social ⏩️ hdl.handle.net/11245.1/5ba777… Thank you @gio-marchegiani.bsky.social for being here with excellent discussion!

I see #pancreas everywhere - Japan 🇯🇵 edition #HPBSky

🇯🇵 My keynote lecture at the 37th Japanese Society of HPB Surgery From 🔮 prediction to 🧯prevention of complications in pancreas surgery… a risk based approach to 🐳 POPF assessing POH 🧪 and PPAP! Thank you for having me, HPB conferences in Japan are simply impossible to beat 🤯

My invited talk at @EAHPBA 2025 🇮🇪 was about IPMN 🍇 and related carcinoma A very slippery 🧽 topic!!! Indeed 2️⃣ different entities in 1️⃣… IPMN derived cancer follow distinct 🧬 pathways 🆚 conventional PDAC but are way less explored (NOT a single RCT) 👉 knowledge gap!

Super excited to meet this fantastic Pancreas star ⭐️ at the EAHPBA congress right from the @myueg.bsky.social presidency!!! Thank you @maloehr.bsky.social United for the pancreas, always!

🔵 The European-African Hepato-Pancreato-Biliary Association (E-AHPBA) mentorship program is ready to take off 🛫 again! So excited to serve as a mentor also for the second edition after a previous successful journey

IPMN 🍇 without HRS and long term risk of cancer development @bmj.com 🇯🇵 2.5k pts > 5 years surveillance 🫧 IPMN size and growth predict cancer within 5 years 🤏 MPD diameter at 5 years predicts cancer after 5 years gut.bmj.com/content/74/6...

🚨 From @ascocancer.bsky.social 2025 👉 Preop chemo with PAXG 🆚 mFOLFIRINOX for extending event-free survival (EFS) in resectable or BR PDAC (phase 3 CASSANDRA trial) 🆙 PAXG 3-year EFS 31% vs. 13% P = .003 🫸 Immature analysis for survival but.. future practice changing?! 🧐 @ascopost.bsky.social

Postop ⬆️ amylasemia and acute pancreatitis 🧪 systematic review and meta analysis 🐳 POH predicts POPF ⚡️ PPAP causes POPF, DGE, PPH and mortality 👉 Check amylase early and get ready to mitigate 🧯postop complications! #HPBSky #SurgSky www.sciencedirect.com/science/arti...

✂️ Arterial resection and divestment 🔟 year comparative study in @bjsopen.bsky.social 🇯🇵 Analysis of 200 PDAC + artery 👗 Divestment (120 cases) most used in first 5 years 🎖️Last 5 years ⬆️ Neoadjuvant chemo + resection ⬇️ complications 👍 academic.oup.com/bjsopen/arti...