📢 Great news! The World Scleroderma Foundation, which does incredible work promoting research in scleroderma and supporting patients globally, has selected our colleague's latest research for a special Basic Science webinar! 🔬🧬
Gonzalo Borrego-Yaniz
@goboru.bsky.social
Genomics and epigenomics to better understand giant cell arteritis and other rheumatic diseases 🖥️🧬 Philosophy and sciart enthusiast. 🏳️🌈 PhD Student at IPBLN-CSIC in Granada, Spain. He/him
No publicar los resultados negativos es una mala práctica científica que deriva de la forma en que está estructurado el sistema de publicaciones (1/2)
❗ Sanidad confirma que la homeopatía es un “peligro para la salud”: “Su eficacia no supera al placebo”
Sanidad confirma que la homeopatía es un "peligro para la salud": "Su eficacia no supera al placebo"
Tras una revisión, la Agencia Española de Medicamentos y Productos Sanitarios concluye que "la evidencia es insuficiente para hacer una recomendación de tratamiento" con estos productos, cuyo principa...
eldiario.es
How many people will die from diseases that would otherwise have been preventable
What causes more women to develop autoimmune diseases? Currently, the explanation normally includes: hormones, chrX and sex differences in the immune system
Doing science requires us to speak 2 different languages: (1) Day science language is a highly precise language for designing & executing experiments; while (2) Night science language uses analogies & anthropomorphizes to give us intuitions about the unknowns we explore. (Night Science recap, Day 4)
El Comité de Igualdad, Diversidad e Inclusión del IPBLN ha organizado un un café informal donde se ha hablado sobre la inclusión de personas LGTBQIA+ en ciencia: algunos de los retos que existen y qué hacer para apoyar mejor a las identidades LGTBQIA+ en nuestros laboratorios.
🧬 Excited to share our new preprint! We characterized CD4+ T cells in #SystemicSclerosis using #SingleCellRNAseq, revealing IFN-driven activation, Treg dysregulation, and Th2/Th17 expansion in disease. 📄 www.biorxiv.org/content/10.6... #scRNAseq #Immunology #SSc
biorxiv.org
At today’s WIP Seminar, Gonzalo Borrego-Yaniz ( @goboru.bsky.social ), a PhD candidate from Dr. Ana Márquez’s lab, presented their latest research on giant cell arteritis, a rare inflammatory disease that mainly affects older adults.
New online! Gene regulatory networks: from correlative models to causal explanations
Gene regulatory networks: from correlative models to causal explanations
Nature Reviews Genetics, Published online: 09 March 2026; doi:10.1038/s41576-026-00939-1In this Perspective, Maizels and Briscoe discuss the limitations of current models of gene regulatory networks and outline solutions to harness data abundance without compromising explanatory power.
dlvr.it
Over the course of 2025, UKB researchers were forced to move all of their data analysis to the cloud rather than working with local copies. What was the effect of this move on scientific output? Here is a simple first pass at answering that question.
Heritability of intrinsic human life span is about 50% when confounding factors are addressed www.science.org/doi/10.1126/...
The February 2026 issue of #ScienceImmunology is out! This month's cover highlights how the cohesin complex shapes genome organization in dendritic cells to regulate their differentiation and function. https://scim.ag/4agVpT8
🧑🏻🎓El Jornal Andaluz | Proyecto de Ley Universitaria para Andalucía: más precariedad para el más precario.
Proyecto de Ley Universitaria para Andalucía: más precariedad para el más precario
Estamos siendo testigos de una acelerada precarización del colectivo del profesorado sustituto
elsal.to
#Women are underrepresented in academia, especially in #STEMM fields, top institutions & in senior positions. Analysis of millions of biomed & life science articles reveal that female-authored articles spend longer under review than comparable male-authored ones @plosbiology.org 🧪 plos.io/4658FZN
Hoy en @elpais.com @manuelansede.bsky.social se hace eco de un estudio depositado en #arxiv que analiza la proliferación de números especiales en algunas revistas científicas en las que el editor que coordina, hasta en un 33% de los casos, es también autor de un artículo. elpais.com/ciencia/2026...
Miles de científicos hinchan su currículum con estudios autopublicados que cuestan millones de euros de dinero público
Un análisis de 100.000 números especiales de revistas académicas revela que uno de cada ocho está lleno de artículos de autobombo del propio editor, sobre todo en la editorial MDPI
elpais.com
Our new paper (with @biotay.bsky.social) is out and on the cover story of @currentbiology.bsky.social !!!! Veronika, a Carinthian mountain cow flexibly uses a “multi-purpose tool” to scratch herself. A video and more information will follow in the comments. www.cell.com/current-biol...
1/ Women scheduled surgery after being told they had rare BRCA1 variants. The genetic test was wrong. University of Exeter analyzed 50,000 samples to find out how often this happens. The results should worry anyone who's downloaded their 23andMe raw data.
Science journals retract 500 papers a month. This is why it matters
Science journals retract 500 papers a month. This is why it matters
A small team of volunteers is tracking thousands of falsified studies, including cases of bribery, fraud and plagiarism
thetimes.com
Seeking scientist volunteers for the 2026 spring semester! Want to practice science communication and help author a 🌟comic🌟 about your research? Apply by 1/25. Please share widely. bit.ly/comicscollabspring2026
Your occasional reminder that I keep a curated list of resources for scientific writers that I find helpful - books, blogs, software, all kinds of things. Here it is:
Writing Resources
Writing is a huge part of any career in science, and for many writers – no, for most writers – it’s a daunting challenge. But it’s not a challenge that you have to tackle alone. That’s a lesson I w…
scientistseessquirrel.wordpress.com
Proteoform medicine: characterizing and targeting protein forms in human disease go.nature.com/45P6t8z #Review by Jennifer A. Korchak, S. Stephen Yi, Neil L. Kelleher (@nlkproteomics.bsky.social), Nidhi Sahni & Gloria M. Sheynkman #proteomics
Proteoform medicine: characterizing and targeting protein forms in human disease - Nature Reviews Genetics
Proteoforms are the diverse protein molecules produced from a single gene whose primary sequence and composition can be diversified by genetic, transcriptomic, translational and post-translational var...
go.nature.com
Now published online! doi.org/10.1002/art....
Genome‐Wide DNA Methylation Study Reveals Specific Signatures in the Affected Arterial Tissue of Patients With Giant Cell Arteritis
Objective Giant cell arteritis (GCA) is a large-vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by i...
doi.org
Gonzalo Borrego-Yaniz@goboru.bsky.social · 11mo agoNew paper just out (online first) in Arthritis & Rheumatology! 🎉 We mapped the epigenetic changes (DNA methylation) in GCA-affected arteries. Largest cohort to date; findings point to new pathways relevant to disease mechanisms 🧵 Read: doi.org/10.1002/art.... cc @ipblncsic.bsky.social
Sobre nuestro último estudio de metilación del ADN en arterias de pacientes de arteritis de células gigantes!! 👇🏼👇🏼
CSIC Andalucía@csicandalucia.bsky.social · 9mo agoDescubren señales moleculares en el ADN que explican la inflamación crónica de las arterias a partir de los 50 años El @ipblncsic.bsky.social identifica también células inmunitarias “agotadas” que podrían explicar por qué la inflamación persiste en la arteritis de células gigantes t.ly/tTyjB
Reproducible single-cell annotation of programs underlying T cell subsets, activation states and functions www.nature.com/articles/s4...
Gracias a un superordenador cuántico, la entidad está en condiciones de asegurar que la letra «I» de sus siglas significa «investigación». Puedes leer la información completa en la web: www.elmundotoday.com/2025/10/el-c... Contenido patrocinado por @csicdivulga.bsky.social.
Take a look! Useful for quick reference and if you get lost with all the -seq omic technologies 😱
Ming Tommy Tang@tommytang.bsky.social · 10mo agoSequencEnG: An interactive learning resource for next-generation sequencing (NGS) techniques education.knoweng.org/sequenceng/ It is impossible to be an expert of all those data types but once you have the core solid foundation you can learn how to analyze a new data type as needed
