💩-post incoming. At Outpost Bio, we are trying to decode the gut microbiome - part of my job is getting as many ppl to poop for me as I can. I wrote a perspective piece to document my learnings on the poop collection process: For the Poop-Curious - Outpost Bio share.google/wUaJSYuVyZeq...

For the Poop-Curious - Outpost Bio

Outpost is building the AI layer for human microbiology. 

Our lab-in-the-loop models can decode the microbiome and transform modern medicine.

share.google

Curious if any Boston based folks know where to source used lab equipment these days? I recall an awesome auction site, but am having trouble finding it. Thinking multichannel pipettes and regular pipettes, scale, stir plates, etc.

What a cool thing it was to write a guest blog post for Small Things Considered as a graduate student. I have never had such a great editor as Elio Schaecter. ♥️

STCmicrobeblog@stcmicrobeblog.bsky.social · 9mo ago

a special treat for biofilm aficionadas y aficionados 👇 #MicroSky we're glad to have restored your timeless "😊-blog" from 2012 now, heidi @heidiarjes.bsky.social smallthingsconsidered.blog/schaechter/2...

Halloween fun: My Toto loves people and enthusiastically greeted all the people giving out candy on our walk home - she didn't need treats, she was the treat! 😆

Advice needed: I'm currently using Zotero to organize papers at my company. A colleague finds the user interface clunky, and his network suggested paperpile. Anyone have opinions? We will be using it to store papers for reading and commenting and citations. Pic of Mickey in a sweater for attention.

An important application of generative A.I. is facilitating discovery to override antimicrobial resistance with newly designed antibiotics, as demonstrated here for in vivo effectiveness vs S. aureus and N. gonorrhoeae www.cell.com/cell/fulltex...

Ever wondered why some antibiotics are made by Streptomyces on agar plates but not in liquid cultures? Read this work on redox control of antibiotic biosynthesis. Led by katienoble241.bsky.social and Rebecca Devine, and in collaboration with @barriewilks.bsky.social journals.asm.org/doi/10.1128/...

It’s too late to save these lost young lives in Texas, but not too late to avert the next tragedy that could be fully avoided. It’s one thing to say you’re making things more efficient and quite another to gut something essential with no replacement. Turn the f’ing lights back on! /fin

Advice needed. I'm in the market for a new laptop. I've had macs in the past, but am slightly leaning PC. Any recommendations for a computer that is a good value for what you get?

This is Ripley. He was nervous about taking the stairs. May have panicked a bit. 12/10

When public health works, “nothing” happens. People stay healthy. People go on living.

Hank Green@hankgreen.bsky.social · 2y ago

A tricky thing about modern society is that no one has any idea when they don’t die. Like, the number of lives saved by controlling air pollution in America is probably over 200,000 per year, but the number of people who think their life was saved by controlling air pollution is zero.

I had not heard or realized this before. Good to know: www.nytimes.com/2022/02/02/r...

Why Gardeners Should Stop Using Peat, and What to Use Instead (Published 2022)

Finding a substitute for peat is a little like making your first cake without gluten. Here’s what the experts advise.

nytimes.com

Helen Czerski@helenczerski.bsky.social · 2y ago

Spring reminder, as people start to think about gardening: NEVER buy compost with peat it in (inexplicably still on sale). If it does not say "peat free" in big letters, do not buy it. Peat is incredibly valuable in peat bogs, for rare biodiversity and as a carbon store. Don't put it on your garden!

One of these things is not like the others

Pretty cool! Why was the previous thought that they would toggle? It seems more adaptable to quickly changing O2 and S availability to have both running simultaneously if both terminal acceptors are there (small cost to producing the proteins to carry out both)?

ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ@nizet.bsky.social · 2y ago

[̲̅P][̲̅A][̲̅R][̲̅A][̲̅D][̲̅I][̲̅G][̲̅M] [̲̅S][̲̅H][̲̅I][̲̅F][̲̅T] 𝘏𝘺𝘥𝘳𝘰𝘨𝘦𝘯𝘰𝘣𝘢𝘤𝘵𝘦𝘳 isolated from Yellowstone hot springs use both oxygen (aerobic) and elemental sulfur (anaerobic) respiration AT THE SAME TIME. Until now, cells were thought to toggle between the two—not do both simultaneously www.nature.com/articles/s41...

Welcome to the Bluesky account for Stand Up for Science 2025! Keep an eye on this space for updates, event information, and ways to get involved. We can't wait to see everyone #standupforscience2025 on March 7th, both in DC and locations nationwide! #scienceforall #sciencenotsilence

I wish I'd made a stronger statement: this headline is a cowardly way to describe the ongoing destruction of science & pretty rude coming from the American Assoc for the Advancement of SCIENCE that will happily charge >$5,000 to publish in one of the most gatekept scientific journals in existence

Julia Willett@jlewillett.bsky.social · 2y ago

"downsizes" is a weak way of saying "forced to cancel dozens of programs, which jeopardizes future STEM careers of talented undergrads" @science.org www.science.org/content/arti...

Diversity is our greatest asset, even if the government disagrees… They not like us! POC in STEM are here to stay. They tried to rig the game but you can’t fake influence! Mustard on the [Be][At] bro. Happy Black History Month!

You missed our series about unnoticed, but influential female scientists in microbiology that were honoured by naming a bacterium after them? Here is the basic information about the 26 women and their groundbreaking work 👉 www.dsmz.de/collection/honouring-women-in-science #herstory #WomenInScience

Lentils ❤️ mycorrhizal fungi. More nodules and greater plant biomass already evident on the inoculated plants at the bottom, compared to non-inoculated up top, in this Australian lentil variety 👌🏼

Neat - I'm looking forward to reading this!

Franciska de Vries 🟥@frantecol.bsky.social · 2y ago

It’s out!! We subjected soils from 30 different locations across Europe to extreme events and found that soil fungal and bacterial communities showed consistent responses that could be predicted from their origin! With @knightjar.bsky.social and many collaborators! www.nature.com/articles/s41...

Crazy stuff in PNAS dental plaque bacterium 𝘊𝘰𝘳𝘺𝘯𝘦𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘮𝘢𝘵𝘳𝘶𝘤𝘩𝘰𝘵𝘪𝘪 can divide into an unprecedented 14 daughter cells at once—then each daughter cell starts growing immediately in a rare process called multiple fission, achieving 0.5 mm per day of expansion www.snexplores.org/article/bact...

These mouth bacteria use a new type of cell division to make 14 cells at once

The newfound strategy seen in C. matruchotii might help oral bacteria recover lost territory after each eviction by toothbrushing.

snexplores.org

Any recommendations for shows to binge? I'm subscribed to Hulu and Disney+ at the moment and looking for engaging shows to help me get through the winter.

I'd like to learn a programming language to help with data analysis. My company is a scrappy startup and Matlab (the language I know) is too expensive. Is Python the obvious choice? Any advice on learning Python with prior Matlab knowledge?

Science folks-please amplify 🧪 PhD students Matt Cope-Arguello and Jiayu Li (Manikantan lab) collaborated to quantify the biophysics/rheology of the goopy colonies of #Raltonia wilt pathogens. Are there other bacterial colonies (or other biological goops) that drip? Thanks! youtu.be/ECz8aN5d58I

Goopy colonies of Ralstonia wilt pathogens drip when plates are inverted

Note: This video was captured on a cell-phone using a feature to speed-up the video, so these colonies are dripping faster than they do in real-time. The rat...

youtu.be

by Christoph   ...Here now, it's again about C. acnes, but this time about se­ver­al strains com­pet­ing for growth in hu­man hair fol­li­cles, pores. An eco­lo­gi­cal fa­mi­ly af­fair, so to speak. Read more > tinyurl.com/5n92ws6n #MicroSky 🦠🧫

This dapper dude and I are day tripping in Salem, MA. Any tips for what to do?

Respiratory inhibitors triggered biofilm dispersal in Pseudomonas aeruginosa, making the cells more vulnerable to antibiotics. 💥 - In @AppEnvMicro (#AEM) journal journals.asm.org/doi/10.1128/...

There is a new 🐁 gut bacterium on the block that likes to hang out with other bacteria that feed it with taurine and bullies some pathogens Please welcome Taurinivorans muris 💩🦠🧫 #Taurinivorans #taurine #sulfide #H2S #bileacids #metabolism #microbiome #pathogen #prophage

Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut - Nature Communicat...

Authors utilise a multi-omics approach for the ecophysiological characterization of a taurine-respiring mouse gut bacterium.

nature.com

Anyone have an invite code they can share? I'm still too new and a friend wants in. Pm me it (assuming sky supports pms 🙂) Thanks in advance!