In a new study, @hheyne.bsky.social and her team identified a Finnish-enriched missense variant in the SCN5A gene that acts like a natural lifelong cardiac sodium channel blockade, decreasing the risk of cardiac arrhythmias while also having some negative effects. hpi.de/en/article/h...

HPI study finds advances in the treatment of heart disease

HPI researchers Dr. Henrike Heyne, Julian Wanner and their team discover gene variant that acts like heart medication. Their study has now been published.

hpi.de

Check out our new article in #Circulation on an astonishing genetic variant in the ion channel #SCN5A that enables us to learn about #cardiac-arrhythmia and their treatment with sodium channel blockers. @finngen.bsky.social www.ahajournals.org/doi/10.1161/... Congrats to @jwanner.bsky.social

Leveraging a Genetic Proxy to Investigate the Effects of Lifelong Cardiac Sodium Channel Blockade | Circulation

BACKGROUND: Atrial fibrillation and other cardiac arrhythmias pose a major public health burden, but prevention remains difficult. We investigated a genetic variant that we found to act like a natural...

ahajournals.org

I'm setting up my lab at @hpi.bsky.social, on the edge of vibrant Berlin! PhD/postdoc positions in AI for safe synthetic biology & infectious diseases (AMR), in collab with @melanianowicka.bsky.social. Apply by Feb 24: email firstname.lastname@hpi.de with “[Open-25]” in the subject. DM for details!

We’re excited to share that our paper on rapid molecular classification of brain tumors has just been published in Nature Medicine!

Check out this great talk by @franriss.bsky.social (PhD student in my lab) on "Comparing protein language models through embedding space comparison" in the famous MIA meeting. Thanks so much to Sumaiya Iqbal for co-supervising and hosting her at @broadinstitute.org www.youtube.com/watch?v=y747...

MIA Lightning Talks (2025)

YouTube video by Broad Institute

youtube.com