3D super-res microscopy reveals ultrastructure of asymmetric adherens junctions between leader & follower cells in angiogenesis – BIN1 & SNX9 are regulators 📹 Vera Janssen et al University of Amsterdam in @jcb.org ➡️ bpod.org.uk/archive/2026...
Stephan Huveneers
@huveneerslab.bsky.social
Associate Professor at Amsterdam UMC, University of Amsterdam / Vascular Biology / Mechanotransduction / Junctions / Adhesion / Cell migration / Angiogenesis / Atherosclerosis / Capillary malformations / https://www.medicalbiochemistry.nl/stephan-huveneers
How do endothelial cells maintain their connections? Together with the team of @vessel-integrity.bsky.social, we used crispant zebrafish to reveal that SNX9 controls endothelial cell-cell junction dynamics during sheet migration in the developing common cardinal vein. rupress.org/jcb/article/...
From those junctional BAR proteins BIN1 and SNX9 emerged as novel regulators of front-to-rear polarity in follower cells during endothelial collective migration. rupress.org/jcb/article/...
In this study, by performing an overall BAR protein localization screen, we identified a variety of BAR protein to be recruited to asymmetric junctions. rupress.org/jcb/article/...
How do endothelial cells interact while migrating? Together with @jesseaic.bsky.social @scopeshifu.bsky.social @aicjanelia.bsky.social, we used #Cryo-SIM and #FIB-SEM to reveal a surprising diversity of nanoscale plasma membrane curvatures at asymmetric junctions. rupress.org/jcb/article/...
During vascular development endothelial cells migrate collectively while remaining connected to one another via asymmetric adherens junctions. rupress.org/jcb/article/...
We are very proud to share our latest work from @verajanssen.bsky.social and @aangulou.bsky.social @amsterdamumc.bsky.social, now published in @jcb.org! We are grateful to the entire team and for the support from NWO and ZonMw. More details in the following posts.
Janssen, Angulo-Urarte, et al. @huveneerslab.bsky.social @uva.nl show that nanoscale membrane curvatures at asymmetric endothelial cell–cell junctions serve as a scaffold to recruit BAR proteins, including BIN1 and SNX9, during collective migration. rupress.org/jcb/article/...
The van Leeuwenhoek Centre for Advanced Microscopy (LCAM) organises the next edition of the "Functional Imaging" course at the University of Amsterdam (UvA), the Netherlands at Oct 5th-16th 2026. More info at: www.microscopycourse.nl?page_id=652
LCAM Functional Imaging (annual) – Microscopycourse
microscopycourse.nl
We are hiring! Are you an ambitious postdoc with a background in vascular bioengineering and cell biology? Then please join our team at Amsterdam UMC and help unravel the mechanisms that govern vascular integrity. #embobuildnetworks #vascularbiology #EVBO werkenbij.amsterdamumc.org/en/vacatures...
Vacatures - Postdoc Vascular Biology - Amsterdam UMC
Are you an ambitious scientist with a background in vascular bioengineering and cell biology? Join our team at Amsterdam UMC and help unravel the mechanisms that govern vascular integrity.
werkenbij.amsterdamumc.org
Calling all vascular biologists! Join us for cutting edge science at #Angioscience26 in gorgeous Seeon, Bavaria. Awesome speakers, intimate setting, many talks from abstracts. Deadline June 15th to register! vwfb.de/start/regist...
🚨 #IVBM2026 abstract deadline extended! 🚨 You now have until 29 May 2026 (11:59 PM ACST) to submit abstracts for oral & poster presentations. Join the global vascular biology community for cutting-edge science, networking & collaboration. #VascularBiology
Thank you to everyone who joined 'Building networks: engineering in vascular biology' at EMBL Barcelona last week. It was a fantastic few days of inspiring science and a great reminder of how rapidly the #VascularBiology and #Bioengineering communities are evolving together 🧬🧪 #EMBOBuildNetworks
Building Networks: Engineering in Vascular Biology As we begin the final day of the meeting, we hope all participants have enjoyed this truly engaging and inspiring event. with Kristina Haase, Katie Bentley, & Christopher Chen #EMBOBuildNetworks @events.embl.org
@huveneerslab.bsky.social highlights recent work from Mayo et al. (doi.org/10.1083/jcb....) identifying Scribble as a regulator of endothelial #AdherensJunctions during #angiogenesis. rupress.org/jcb/article/... #Adhesion #Cytoskeleton #Development
For those interested in endothelial junctions: our latest paper is out in iScience, and it includes a mass spectrometry based VE-cadherin interactome! Turns out that there are many more molecular intractions going on than just with the catenins… See: www.sciencedirect.com/science/arti...
Last day to register for the EMBO Workshop "Building networks: Engineering in vascular biology" in #Barcelona, #Spain, 13–15 May 2026. https://www.embl.org/about/info/course-and-conference-office/events/evb26-01 #EMBOBuildNetworks #EMBOevents 🧪
We are excited to welcome Stephan Huveneers (University of Amsterdam) to our @sfb1348.bsky.social seminar @uni-muenster.de. He will speak about "Force-dependent regulation of endothelial adhesion in vascular development and disease”. Everyone is welcome! More: www.uni-muenster.de/SFB1348/en/i...
📩 Late with your abstract for 'Building networks: engineering in vascular biology'? You now have an extra week to send it over! 🔬 Join us at EMBL Barcelona this May to meet researchers working at the intersection of engineering and vascular biology. #EMBOBuildNetworks s.embl.org/evb26-01-bl
Very pleased with our newest publication! In this study, we identify the Calcineurin-NFAT-DSCR1.4 signaling pathway as a druggable driver of capillary malformations caused by the GNAQ p.R183Q mutation, which is associated with port-wine stains and Sturge-Weber syndrome. 🔗 article: rdcu.be/e2gRC
Join us in Amsterdam for a FEBS advanced course on "Functional Imaging of cellular dynamics" from 31st of May - 6th of June 2026 Info: microscopy2026.febsevents.org
🔬 Join us in Barcelona to meet researchers working at the intersection of engineering and vascular biology and discover cutting-edge techniques in spatial omics, advanced imaging, and the use of AI in vascular research. #EMBOBuildNetworks 13 – 15 May 2026 Register by 4 Feb: s.embl.org/evb26-01-bl
🔬 Join us in Barcelona to meet researchers working at the intersection of engineering and vascular biology and discover cutting-edge techniques in spatial omics, advanced imaging, and AI. #EMBOBuildNetworks @events.embl.org 13 – 15 May 2026. Register by 4 Feb: s.embl.org/evb26-01-bl
Save the date for the EMBO Workshop: Building networks: engineering in vascular biology EMBO Workshop www.embl.org/about/info/c... May 13-15 2026, Barcelona. Abstract deadline, Feb 4th!
Building networks: engineering in vascular biology
embl.org
Big news, EVBO community! Our BLACK FRIDAY membership deal is live until 31 Dec 2025: 🔹 3-year full membership: €120 🔹 PhD/postdoc: €75 Join now ➜ evbo.org/index.php/me... Plus, members get access to 3 exclusive vascular biology workshops in 2026. Don’t miss out!
Membership - European Vascular Biology Organisation
EVBO needs your support to further expand its activities and invites you to become a member.EVBO develops scientific, educational, training and networking activities to potentiate vascular biologists…
evbo.org
🎓 Dr. Hooglugt! On October 23rd, Aukie successfully defended his PhD thesis, “Balancing forces: endothelial mechanobiology in vascular dynamics and disease. A huge congratulations from a proud team of supervisors @reinierboon.bsky.social, @huveneerslab.bsky.social & Dr. van der Stoel.
Goodmorning all! The EVBO board is back online! Please see our amazing speaker list and reserve the following dates for the upcoming EVBO autumn seminars. You can registration for the Zoom through the link in the email from our EVBO secretary.
The integrin odyssey – a journey full of fundamental discoveries url: journals.biologists.com/jcs/article/... Great to start the day while reading this #integrin odyssey.
The integrin odyssey – a journey full of fundamental discoveries
Summary: This Perspective highlights the key discoveries in integrin research that laid the foundation for a successful field.
journals.biologists.com
Our new series of online EVBO seminars is kicking off! Bimonthly Vascular Biology on Tuesday afternoons. Want to join: go through the EVBO website for registration, evbo.org/index.php/ev...
EVBO Online Seminars - European Vascular Biology Organisation
Recordings EVBO seminar 18th June 2025 EVBO seminar 5th June 2025 EVBO seminar 22nd May 2025 EVBO seminar 8th May 2025 EVBO seminar 17th April 2025 Previous EVBO online seminars
evbo.org
🍂 Kicking off the fall seminar series! 📢 EVBO seminar, Tue 16th of September: Profs. Lena Claesson-Welsh & Hellmut Augustin. Don't miss it!