Clinical research and patient care go hand in hand. Hear Dr Fatima Dhalla from the Holländer Group discuss why in this excellent interview.

BSI Clinical Immunology Professional Network@bsi-cipn.bsky.social · 2w ago

How do the best research questions arise? Dr Fatima Dhalla discusses why clinical immunologists are uniquely placed to identify the questions that matter most to patients, and how research can complement a clinical career. Watch the full interview: vist.ly/5c3uy

The Oxford-ZEISS Centre of Excellence in Biomedical Imaging between @kiroxford.bsky.social and the Institute of Developmental & Regenerative Medicine has become the first to acquire the new ZEISS Lightfield 4D system. Read more: www.idrm.ox.ac.uk/news-and-fea...

We were delighted to bring colleagues together to celebrate Prof Paul Riley's election to the Fellowship of the Royal Society. In true IDRM fashion, Paul used the occasion to recognise the many researchers, collaborators and colleagues who have contributed to the Institute's success.

How do immune cells help heal the heart? In the latest episode of the @stemcellpodcast.com, Dr. Simões @simoesfilipa.bsky.social, Group Leader at IDRM and Co-Director of the Oxford Organoid Hub, discusses her research on how macrophages shape heart development, repair, and regeneration.

Stem Cell Podcast@stemcellpodcast.com · 2mo ago

📢 Our next episode is live! Dr. Filipa Simões (@simoesfilipa.bsky.social) at @ox.ac.uk discusses how macrophages shape heart development, repair, and regeneration, and how cellular crosstalk within the cardiac niche influences tissue outcomes after injury. 🎙️Listen now: https://bit.ly/4dYixJs

In a new expert commentary, Associate Professor Thomas Roberts discusses a paper published in Gene Therapy, which examines the progress and challenges of AAV microdystrophin gene replacement therapies for #DuchenneMuscularDystrophy. Read more: tinyurl.com/2rzbyv6s

We are excited to share that Professor Paul Riley has been elected to the Fellowship of the Royal Society, the UK’s national academy of sciences, for his outstanding contribution to regenerative medicine and cardiovascular science. www.idrm.ox.ac.uk/news-and-fea... @oxforddpag.bsky.social

The Oxford-ZEISS CoE in Biomedical Imaging, between the IDRM and @kiroxford.bsky.social at @ox.ac.uk, in collaboration with @zeiss-microscopy.bsky.social, is developing a new cutting-edge imaging technology: Selective Plane Illumination Lattice Light Sheet Microscopy. 🔗https://tinyurl.com/mu6xvpwc

📢Exciting opportunity for postdocs! The IDRM is offering a Transition Fellowship for outstanding researchers at an intermediate/career development stage. Apply now: lnkd.in/eYkYUAhB #FellowshipOpportunity #Postdoc #InterdisciplinaryResearch @paediatrics.ox.ac.uk

Congratulations to Filipa Simões and team on their new publication 👏 #regenerativemedicine #zebrafish #heart

Filipa Simões@simoesfilipa.bsky.social · 5mo ago

Excited to share our #preprint showing that #macrophages in the regenerating #zebrafish #heart are shaped by local cardiac-immune microniches, with a fibroblast-to-macrophage signal promoting regeneration over fibrotic repair www.biorxiv.org/content/10.6... @idrm.ox.ac.uk @oxforddpag.bsky.social

Spring has arrived at the IDRM! As research in developmental biology and regenerative medicine pushes boundaries within IDRM's laboratories, our scientists can take a look outside and enjoy the view of the blossoming trees in our Japanese garden. 🌸 @ox.ac.uk

New research from the Roberts Group @ribomedicine.bsky.social at IDRM explores a new way to increase the body’s own production of BDNF, a key brain protein involved in neuron health, learning and memory. Read the paper: tinyurl.com/ydwxk49d

What a pleasure to host @hsiuchuanlin.bsky.social @crg.eu to @idrm.ox.ac.uk @oxforddpag.bsky.social! We discussed in much depth novel technologies pushing forward the engineering human cell fate space- looking forward to exciting collaborations 🤩 And always a treat to visit @jesusoxford.bsky.social!

Spring has arrived at the IDRM just in time for Green Action Week! We are taking action by promoting our book swap, recycling, and Beauty Banks sustainable initiatives. Our bug houses made for pollinators are spring-ready too — with a ladybird already spotted 🐞 #GreenActionWeek #Sustainability

International Women and Girls in Science Day 👩‍🔬✨ We’re proud to support brilliant women at the IDRM, including Dr Andia Redpath, Dr Inhye Park, Dr Sophie Payne and Dr Susann Bruche, who recently took part in the EMBO Laboratory Leadership Course. Read more 👉 tinyurl.com/mrxurm52

On #TimeToTalkDay, we’re proud to support open conversations about mental health. Will Vaulks, who recently gave a talk at the IDRM, and Prof Willem Kuyken remind us that sharing experiences can help reduce stigma around mental health challenges. 📽️ www.youtube.com/watch?v=8Hkd...

Time to talk

YouTube video by University of Oxford

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In December, we hosted the EMBO Lab Leadership Course with NDM and the Dunn School of Pathology. We spoke to Dr Sophie Payne, Dr Susann Bruche, Dr Inhye Park and Dr Andia Redpath about what they learned about leadership and leading their own research teams. Read more: tinyurl.com/mrxurm52

This week’s scientific image, submitted by the Holländer Lab, is titled “The birth of immunity: spatial transcriptomics illuminating the thymus at E14.5.” The image uses spatial transcriptomics to visualise gene expression patterns across the embryonic thymus at day 14.5.

This week’s scientific image, created by Ehsan Razaghi, DPhil student, Simões lab, is titled “Immune-mediated spatial orchestration of cardiac regeneration in zebrafish, 5 days post cryoinjury.” His research focuses on the role of the immune system in heart regeneration after myocardial infarction.

A huge congratulations to Joe Day, former Communications & Operations Apprentice and current Business Development & Engagement Officer at the IDRM, on winning the Shining Star Apprentice Award at the 2025 University of Oxford Apprenticeship Awards!

This week’s scientific image, contributed by Dr Emma Haberman from the Riley and Holländer groups, is titled “Atrial Architecture.” Her work investigates the role of T cell-mediated autoimmunity in the progression of heart failure after myocardial infarction.

New from Dr Matthew Stower and the Srinivas Group at IDRM 👇 Calcium signalling turns out to be essential for setting up the embryo’s anterior-posterior body axis. Using light-sheet microscopy, the team captured calcium activity in early mouse embryos. Read more: tinyurl.com/5999kkm8

This week's scientific video, created by Dr Shifaan Thowfeequ from the Shankar Srinivas lab, is titled “Chasing the wave – in search of the origins of the first heartbeat.” The video captures the mechanical and chemical dynamics of an embryonic chick heart as it first forms and starts to beat.

Thanks to everyone who joined us for last week’s Get To Know Each Other event at the IDRM, and to all our fantastic speakers and poster presenters who made the afternoon such a success!

This week’s featured scientific image, "From blueprint to beating - engineering human cardiac development in a dish," comes from Selin Tüzüner (Simões Group), whose work was selected as a finalist in the BHF Reflections of Research competition. Read more: lnkd.in/dQ4rZR9t #ScientificImaging

✨ Monthly Featured Member ✨ Meet Mary Deadman, who recently retired after an incredible 44 years at the University, most recently as Laboratory Manager for the Holländer Group. Mary has supported countless projects and colleagues throughout her career. 🔗Read more: shorturl.at/SWhc5

This Christmas, we’re teaming up with the Department of Paediatrics to support #Sleigh2Give and bring festive cheer to children in hospitals and families across Oxfordshire. 🎁✨ Donate brand new, unwrapped gifts by 12 Dec to help make the holidays a little brighter.

Today’s scientific image of the week, “Cellular Hummingbird”, comes from Elizabeth Figueroa-Juárez. 🧫 She’s modelling atherosclerosis in vitro using hiPSC-derived endothelial cells. ✨ The colours and shape reminded her of hummingbirds—“gods’ messengers from the afterlife,” in Mayan legend.

Today’s #ScientificImage — “Where Vessels Begin,” comes from @degrainger.bsky.social, a postdoctoral researcher in IDRM's Stone group. 💬"We are working to understand how blood and lymphatic vessels form during embryonic development and how organ-specific characteristics of these vessels arise."

Last week's spooky creations, courtesy of IDRM's Mommersteeg Group, were carved just in time for Halloween! @tillymommersteeg.bsky.social

Our Institute for Desperately Regrowing Moustaches @idrm.ox.ac.uk is raising money for men’s mental health, suicide prevention, and prostate and testicular cancer awareness by growing moustaches. Please donate on our Movember page if you're able! movember.com/t/institute-...

Institute of Developmental and Regenerative Medicine (IDRM)'s Mo Space

Movember, the month formerly known as November, is a moustache growing charity event held during November each year that raises funds and awareness for men's health.

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