Joseph Buxbaum
@jdbux.bsky.social
Director, Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai. Shakuhachi student.
Some good news! Not a done deal, but important step. If you wondered if submitting your comments on the OMB rules change mattered, the answer is a resounding YES
Sam Wang@samwang.bsky.social · 2w agoThis may dramatically slow down the attacks on science. It also provides a template for how to prevent the federal government from becoming a patronage state. It’s a big deal!
Yaaas! Good news on a Sunday! The senate moves to temporarily ban the OMB proposal that would allow political appointees in charge of approving federal grants, especially #NIH grants. Recall that the OMB rule yielded 500k comments, 95% of them against it. 🧪 www.politico.com/news/2026/08...
Senate finalizes funding patch that would block Trump’s grant overhaul
Language is included to delay the president’s move to put political appointees in charge of grant approval.
politico.com
This is an outstanding result, but we’re not done yet! The NSF update is still open for comment and not directly impacted. Keep the pressure up! fight2win.standupforscience.net
Stand up for Science
Stand up for Science
fight2win.standupforscience.net
Colette Delawalla, PhD@cdelawalla.bsky.social · 2w agoTHIS IS WHAT PEOPLE POWER ACCOMPLISHES! Thank you thank you thank you to everyone who wrote comments, contacted Congress, and yelled! This is OUR WIN! @standupforscience.net www.politico.com/news/2026/08...
Musk says not a single person has died due to him axing USAID. Sadly, part of my job involves tracking aid spending. So here’s a thread with just some of the people who lost their lives because of USAID cuts
The Science That Turned Lizard Venom Into GLP-1s Is Under Attack www.nytimes.com/2026/06/20/o...
Opinion | The Science That Turned Lizard Venom Into GLP-1s Is Under Attack
nytimes.com
Large-scale transcriptomic study reveals that eating disorders (ED) and OCD share common molecular substrate in the human brain. ED and OCD converge on cortico-striatal transcriptional programs. Downregulation links mitochondrial function and inhibitory synaptic signaling. doi.org/10.1016/j.ce...
Redirecting
doi.org
My first art credit! 💅 Art director Samuel Velasco and I wanted a new visual metaphor for the genome — not a code or a sequence, but its tangled, twisted physical form. More cool yarn sculptures inside! Also it's a great piece by @philipcball.bsky.social that will change the way you think about DNA
Quanta Magazine@quantamagazine.org · 2mo agoThe human genome is no blueprint or algorithm — it’s something else entirely, something living with promiscuous logic. Can new genomic AI models, such as Evo 2 and AlphaGenome, untangle these tricky knots or will the genome confound them, too? www.quantamagazine.org/why-the-huma...
The human genome is no blueprint or algorithm — it’s something else entirely, something living with promiscuous logic. Can new genomic AI models, such as Evo 2 and AlphaGenome, untangle these tricky knots or will the genome confound them, too? www.quantamagazine.org/why-the-huma...
Why the Human Genome’s Tangled Physicality May Confound AI | Quanta Magazine
Our genetic heritage is not a blueprint or an algorithm, as many biologists have imagined, but something else entirely.
quantamagazine.org
Yet another disastrous move for public education: Shifting the Office for Civil Rights to the DOJ will strip marginalized students of vital protections leaving them more exposed to systemic discrimination, unsurprisingly subverting the core mission of the Office for Civil Rights. #AcademicSky
Trump further guts Education Dept. by shifting oversight of special ed, civil rights
The moves to the federal departments of Health and Human Services and Justice, respectively, would further dismantle an agency that President Donald Trump has vowed to close.
npr.org
📢 The Department of Education is shifting key special education and civil rights responsibilities to other agencies. AFT President @rweingarten.bsky.social responded, calling the move “a dagger to the heart” of the department’s mission to protect the most vulnerable. Read her statement ⤵️
AFT’s Weingarten on Education Department’s Move of Special Ed and Civil Rights Offices to Other Agencies
WASHINGTON—AFT President Randi Weingarten issued the following statement after the federal Department of Education announced it was moving two of its most crucial functions to the Department of Health...
aft.org
Attend the Leena Peltonen Award lecture now at #eshg2026 with Nicola Whiffin from Oxford University and learn About her recent discovieries in rare diseases and the broader inclusion of non-coding variants in clinical genetic testing that led to the Leena Peltonen Award. Congratulations!
new kick in the teeth for US science. These are PROPOSED new rules that just dropped in the federal register. TLDR: would effectively allow political appointees to direct the $ where ever they want. Comments open until July 13.
elizabethginexi.bsky.social@elizabethginexi.bsky.social · 3mo agoSummary of Key Changes in OMB’s Proposed Federal Financial Assistance Rule. Russell Vought is going destroy American Science. elizabethginexi.substack.com/p/summary-of...
www.nature.com/articles/d41...
Key US science panels are being axed — and others are becoming less open
A Nature analysis shows that the Trump administration has terminated more than 100 advisory committees to science agencies — and reduced the transparency and independence of those that remain.
nature.com
an amazing collaboration that identified a completely new pathway in Down syndrome - bioengineer.org/researchers-...
Researchers Link RNA Editing Dysregulation to Abnormal Fetal Brain
A groundbreaking collaborative effort led by researchers from the Icahn School of Medicine at Mount Sinai and the Lieber Institute for Brain Development has unveiled a previously unknown biological
bioengineer.org
An amazing and inspiring collaboration across the Americas shows that the genetic architecture of autism is consistent across diverse ancestral populations. urldefense.proofpoint.com/v2/url?u=htt...
Deleterious coding variation associated with autism is shared across ancestries
Nature Medicine - Genetic analyses in more than 15,000 individuals from across the Americas, including individuals with autism and family members, define the genetic landscape of autism in Latin...
urldefense.proofpoint.com
Delighted to share that our study is now out @cp-cellstemcell.bsky.social www.cell.com/cell-stem-ce... Congrats to Dr. @federicamosti.bsky.social for the culmination of a beautiful thesis!
Species-specific chromatin architecture and neurogenesis mediated by a human enhancer
How human-specific DNA changes shape brain development is poorly understood. Mosti et al. discover a human enhancer, HAR1984, which drives ETV5 and TRA2B expression via human-enriched chromatin intera...
cell.com
Debby Silver@debbysilver.bsky.social · last yr.Sharing our newest study led by the incredibly talented @federicamosti.bsky.social investigating new molecular mechanisms of human brain development. We discover a human-specific enhancer HAR1984 that influences chromatin looping to promote cortical size and folding! www.biorxiv.org/cgi/content/...
Judge Strikes Down Kennedy’s Vaccine Policies www.nytimes.com/2026/03/16/h...
Judge Strikes Down Kennedy’s Vaccine Policies
nytimes.com
How Congress can restore the independence of US science www.nature.com/articles/d41...
How Congress can restore the independence of US science
Members must go beyond reinstating US government research spending and re-establish decentralized governance at the National Institutes of Health and other agencies.
nature.com
