Jesse Aaron
@jesseaic.bsky.social
Manager, Advanced Imaging Center HHMI Janelia Research Campus
Bharathan, Kowalczyk et al. provide the first comprehensive description of the 3D desmosome in A431 epidermoid carcinoma, human mammary epithelial cells, and airway epithelia in volume electron microscopy datasets. rupress.org/jcb/article/... #Adhesion #StructuralBiology
Always great fun doing the #IALSJanelia boot camp. Absolutely phenomenal group of participants!
AIC at Janelia@aicjanelia.bsky.social · last mo.We are grateful to our teaching team and participants for a wonderful two weeks of intense microscopy and image analysis at #IALSJanelia 2026. Many thanks to the @janeliaconf.bsky.social team for the support that made this bootcamp possible!
How do endothelial cells interact while migrating? Together with @jesseaic.bsky.social @scopeshifu.bsky.social @aicjanelia.bsky.social, we used #Cryo-SIM and #FIB-SEM to reveal a surprising diversity of nanoscale plasma membrane curvatures at asymmetric junctions. rupress.org/jcb/article/...
This afternoon's imaging lab at #IALSJanelia is all about subcellular structures, highlighted here by myosin (white) and actin (orange). These membrane ruffles were captured on our lattice light-sheet microscope by @cmhobson.bsky.social
We're kicking off #IALSJanelia 2026 with a keynote lecture by @scopeshifu.bsky.social. Our teaching team is excited to get to know all our participants and start two weeks of talking about microscopy! 🔬
Microscopy beautifully reveals the dynamic nature of biology but quantifying that motion can be tricky! In the latest paper from @aicjanelia.bsky.social, out now in @jcellsci.bsky.social, we present a tool for measuring amorphous motion: OpticalFlow3D journals.biologists.com/jcs/article/... (1/7)
OpticalFlow3D – a tool for measuring amorphous motion in three-dimensional fluorescence microscopy images
Summary: Biological motion can be difficult to define and measure. Optical flow is uniquely suited to this challenge. We provide tools for 3D optical flow and illustrate its use in extracting biologic...
journals.biologists.com
🧪 @aicjanelia.bsky.social and @scientistrachel.bsky.social have just published a new quantitative tool, OpticalFlow3D, for tracking amorphous motion in 3D. Try it out and let us know what you think! tinyurl.com/OpticalFlow3D
My first post here, we have a new preprint out from @aicjanelia.bsky.social! Upright LSFM is fantastic for live imaging, but not amenable to all samples - especially those requiring an air-liquid interface. We worked with Tokai Hit to try to fix that. www.biorxiv.org/content/10.6...
🧪 From ~2500 applications to various international microscopy workshops, we delineate fascinating regional patterns in research foci and microscopy usage across the globe. These data could help form the basis for tailoring microscopy workshop curricula to local needs. tinyurl.com/32c3fzvk
GORGEOUS data from Laura Smithson for #MicroscopyMonday! 🏆 Our #NESM Fall Symposium Poster Winner (Brown Univ., de Graffenried Lab) used customized #FIB-SEM to reconstruct the T. brucei cytoskeleton at 4 nm res — 9,000+ images & 660 GB. @brown.edu @aicjanelia.bsky.social #Microscopy #VolumeEM #EM
We are kicking off a blog series with @focalplane.bsky.social to provide insight into life at the AIC, microscopy careers, image analysis, and more! Read our intro post here: focalplane.biologists.com/2025/11/20/a...
AIC at HHMI Janelia
Introduction to the AIC at HHMI Janelia blog on FocalPlane
focalplane.biologists.com
Wishing everyone a happy #FluorescenceFriday and a #HappyHalloween! This expansion microscopy visualization of blood vessels in a zebrafish is the result of a collaboration between Ellen, Jenny, @nicolasdenans.bsky.social, and @scientistrachel.bsky.social.
Our team is hard at work preparing for #InsightFromImaging 2025! We can't wait to welcome HHMI #HannaGrayFellows to @hhmijanelia.bsky.social next week for lectures, hands-on labs, and activities focused on designing informative and quantitative bioimaging experiments 🔬
The latest AIC Call for Proposals is now open! Deadline is June 16, 2025. Come use @hhmijanelia.bsky.social imaging technology and expertise for FREE. Visit www.aicjanelia.org/apply for details. Before applying, contact us to schedule a technical consultation!
Apply | aicjanelia
Apply to use the advanced microscopes housed at the AIC.
aicjanelia.org
We have an open #opportunity for a BioImage Analyst to join our team! This is an excellent role for a problem solver with an empathetic, collaborative mentality who enjoys partnering with interdisciplinary scientists. Read more and apply here: hhmi.wd1.myworkdayjobs.com/en-US/Extern...
BioImage Analyst
Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute’s Janelia Research Campus is a pio...
hhmi.wd1.myworkdayjobs.com
Harikrushnan Balasubramanian @harikrushnan.bsky.social is a research specialist on Janelia’s new Integrative Imaging team @i2janelia.bsky.social, collaborating with Janelia labs to develop methods & workflows for using light microscopy in biological research. 🧵(1/11) www.janelia.org/support-team...
