Latest from the lab and a fantastic collaboration with Eric Brown's team at @mcmasteriidr.bsky.social. Screening for new antibiotics from actinomycete extracts under nutrient-deprived conditions identifies a megacluster of synergistic antibiotics that target biotin biosynthesis. rdcu.be/fqejG

A Streptomyces megacluster encodes synergistic biotin-targeting antibiotics

Nature - In Streptomyces spp., a conserved biosynthetic gene megacluster produces an arsenal of distinct antimicrobials that converge on bacterial biotin biosynthesis as a naturally evolved...

rdcu.be

Interested in analyzing LC-MS data using Python? 🐍📊 Check out eMZed 3: our framework for building highly customizable and interactive LC-MS data analysis workflows! 📰 Paper: doi.org/10.1093/bioa... 🔗 Website: emzed.ethz.ch

eMZed 3: flexible and interactive development of scalable LC-MS/MS data analysis workflows in Python

AbstractSummary. Liquid chromatography–mass spectrometry (LC-MS/MS) data analysis requires adaptable software solutions to meet diverse analytical needs. W

doi.org

Bioinformatics Advances@bioinfoadv.bsky.social · 2mo ago

🧪 New study in Bioinformatics Advances: "eMZed 3: Flexible and interactive development of scalable LC-MS/MS data analysis workflows in Python"  Find it at https://doi.org/10.1093/bioadv/vbag138  Authors include: @jethrohemmann.bsky.social, @nzamboni.bsky.social

We search for a postdoc focusing on the molecular ecology of #bryophytes 🌱🧬🔬. Join our work @sgn.one Institute for Plant Form and Function and @uni-jena.de 🗓️Deadline: March 29, 2026 👉 More Infos and Apply here: www.senckenberg.de/de/stellenan...

Great and fun community initiative to expand the number of annotated biosynthetic gene clusters in MIBiG!

@nicoleeavalon.bsky.social · 6mo ago

The MIBiG 5.0 Annotathon is coming soon, and registration is now open! 🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise. Register here 👉 forms.gle/C1cWcLHtrjT2...

The MIBiG 5.0 Annotathon is coming soon, and registration is now open! 🧬 Does your research involve biosynthetic gene clusters? Do you love natural product biosynthesis? Do you have an interest in rare & exotic enzymes? We can use your help & expertise. Register here 👉 forms.gle/C1cWcLHtrjT2...

Hiring a postdoc for an exciting collaborative project on drought, microbiomes, chemistry and herbivores IN TREES! In Jena we offer great living and scientific conditions and a strong system for postdoc support and training vai @jsmc-info.bsky.social. Details/apply: jobs.uni-jena.de/jobposting/7...

Great opportunity to contribute to MIBiG!

Mitja M. Zdouc@mmzdouc.bsky.social · 8mo ago

Speaking of MIBiG hackathons: iteration 5.0 it is planned for spring 2026 and registrations are open! Please sign up if you are interested and feel free to share with your colleagues! (7/8) forms.gle/JKsf3XL3d1XN...

Funded PhD position 8/9: Develop scalable moss-bacteria co-cultivations for the discovery and production of new natural products & benefit from the PhD training program ILRS 2.0. Apply by 13 Dec. 🎓 lmy.de/diSOz #PhDOpportunity #ScienceJobs #LeibnizHKI

🎓 Open PhD position at the interface of natural product discovery & biotechnology in our group! In this interdisciplinary project in collaboration with the Bio Pilot Plant, you will develop co-cultivation methods for mosses and bacteria to trigger the production of novel natural products. 🦠↔️ 🌱

Job opportunity Doctoral Researcher (m/f/div) at Leibniz HKI Jobportal

Wissenschaft/Forschung in Jena

jobs.hki-jena.de

Leibniz-HKI@leibniz-hki.de · 8mo ago

Funded PhD position 8/9: Develop scalable moss-bacteria co-cultivations for the discovery and production of new natural products & benefit from the PhD training program ILRS 2.0. Apply by 13 Dec. 🎓 lmy.de/diSOz #PhDOpportunity #ScienceJobs #LeibnizHKI

So once again: if you’re skilled in bioinformatics and/or machine learning, and you’re excited about developing innovative computational methods for analyzing small molecule mass spec data, please apply! bio.informatik.uni-jena.de/mitarbeiteri...

Just wrapped up inspiring days of science and networking at the VAAM Workshop “Biology of Bacteria Producing Natural Products” in Berlin! Our team’s first conference ended on a high note — 2nd prize for best poster! 🥈🥳 Thanks to the organizers @niedermeyer-lab.bsky.social for a fantastic meeting. 🙏

We are hiring! We are going to use some really, really cool new techniques to look at the chemical and spatial dynamics of how the plant micobiome takes shape and what it means. Join us! Apply online until 20th Oct here: www.microverse-cluster.de/files/conten...

🚀 SIRIUS v6.3 is here! We're excited to introduce the latest version of #SIRIUS with powerful new features to enhance small molecule identification. ⬇️ Learn more and download SIRIUS v6.3 today: bright-giant.com/sirius-relea... #SIRIUS6 #MSsoftware #MassSpectrometry #SmallMoleculeIdentID

Times Are Changing, but Order Matters: The @boeckerlab.bsky.social has introduced a groundbreaking two-step method for transferable retention time prediction buff.ly/vcFreLJ #Chromatography #RetentionTime #MachineLearning #SmallMoleculeIdentification

My group at is hiring a PhD student to explore how fungal pathogens that live in the environment will adapt their genomes, acquire new phenotypes, and perhaps even increased infectivity as a result of climate change. Please share! More info and applications at @ jobs.uni-jena.de/vrbup

🚨 We are still looking for a postdoc in Natural Product Chemistry to explore novel molecules from the moss microbiome! 🧪🌱🧫 More information and apply here: jobs.hki-jena.de/jobs/Postdoc...

Stellenangebot Postdoctoral Researcher (m/f/div) in Natural Product Chemistry bei Leibniz HKI Jobportal

Wissenschaft/Forschung in Jena

jobs.hki-jena.de

Metabolomics-guided Natural Product Discovery @ Leibniz-HKI@mnd-hki.bsky.social · last yr.

🚨 We’re hiring a Postdoc in Natural Product Chemistry! 🧪⚗️ Join us to discover and isolate natural products from the moss microbiome and elucidate their structures and biosyntheses. If you're eager to work at the interface of chemistry and microbiology, apply here: jobs.hki-jena.de/jobs/Postdoc...

📣 I’m recruiting a #Postdoc to help us further our understanding on the infection strategies of our human fungal pathogen. If you’re enthusiastic about research, our interdisciplinary group @leibniz-hki.de will be a good fit for you! Please share! jobs.hki-jena.de/jobs/Postdoc...

Job opportunity Postdoctoral Researcher (m/w/div) in “Microbial Infection Strategies” at Leibniz HKI Jobportal

Wissenschaft/Forschung in Jena

jobs.hki-jena.de

Exciting postdoc opportunity for someone in the natural product field interested in using state-of-the-art robotics to automate antimicrobial peptide discovery and engineering! 🤖

Luzia Gyr@luziagyr.bsky.social · last yr.

📢 Curious how automation can accelerate the discovery of novel antimicrobials? Check out the open postdoc position: jobs.hki-jena.de/jobs/Postdoc...

#mzmine 4.7 is now available! This release brings our most significant improvement in memory efficiency to date, unlocking new capabilities for analyzing large-scale datasets. Join us for a live software demo at our booth today and tomorrow at 12:00/noon during #ASMS2025

We had great fun at the company run in Jena yesterday! 🏃‍♀️🏃‍♂️💪 #Firmenlauf2025

🚨getphylo workshop announcement🚨 (Please share!) Are you interested in building genome-scale phylogenies - fast? Or want to explore the evolution of gene clusters? Then getphylo might be the tool for you! I will be running online workshops on the 26th and 27th May. 🧪💻 1/3

🌱 Mosses thrive in extreme environments. At #LeibnizHKI, Jethro Hemmann’s team uses metabolomics to decode moss-microbe interactions in hunt for bioactive #NaturalProducts. 👉 lmy.de/BEXIo @mnd-hki.bsky.social

We're happy to announce that the #antiSMASH v8 paper is out in @narjournal.bsky.social: academic.oup.com/nar/advance-... Many thanks to @kblin.bsky.social, @marnixmedema.bsky.social and many international collaborators!

antiSMASH 8.0: extended gene cluster detection capabilities and analyses of chemistry, enzymology, and regulation

Abstract. Microorganisms synthesize small bioactive compounds through their secondary or specialized metabolism. Those compounds play an important role in

academic.oup.com

My group is looking for a postdoc to explore novel chemistry in the moss microbiome! 🧪🌱🧫 If you have experience in natural product isolation and structural elucidation, apply now. 📅 Deadline: April 30, 2025 More info & apply here: 🔗 jobs.hki-jena.de/jobs/Postdoc...

Job opportunity Postdoctoral Researcher (m/f/div) in Natural Product Chemistry at Leibniz HKI Jobportal

Wissenschaft/Forschung in Jena

jobs.hki-jena.de

Metabolomics-guided Natural Product Discovery @ Leibniz-HKI@mnd-hki.bsky.social · last yr.

🚨 We’re hiring a Postdoc in Natural Product Chemistry! 🧪⚗️ Join us to discover and isolate natural products from the moss microbiome and elucidate their structures and biosyntheses. If you're eager to work at the interface of chemistry and microbiology, apply here: jobs.hki-jena.de/jobs/Postdoc...

Nature research paper: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome https://go.nature.com/4iECjJz

A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome - Nature

A new lasso peptide antibiotic exhibits broad-spectrum activity against Gram-negative and Gram-positive bacteria by interfering with bacterial protein synthesis, is unaffected by common resistance mechanisms and shows no toxicity towards human cells.

go.nature.com

Our Junior Research Group started three months ago! We’ve successfully set up the lab and begun our first experiments. 🧫🧬 Excited to explore natural products produced by bacteria from the #moss microbiome and uncover their bioactivities and roles in microbial interactions! 🌱🦠🧪 #metabolomics

Julia Vorholt wins the 2025 Novonesis Biotechnology Prize for her groundbreaking research on plant microbiomes! Our congratulations to this outstanding achievement! 🎉 biol.ethz.ch/en/news-and-...

Good news: We will have another summer school on non-targeted metabolomics this year! Organized by Martin Hansen and Scott Jarmusch, this year's summer school will be hosted at DTU in Copenhagen from August 18-22, inc. a summer camp style accommodation option at DTU. Sign up: tinyurl.com/NTMS2025