Excited to share our now published paper @cp-cell.bsky.social highlighting advances in modeling the evolution of protein-protein interactions with MSA Pairformer. Big thanks to Zhidian Zhang, Olivia Tang, @eunbelivable.bsky.social @milot.bsky.social @martinsteinegger.bsky.social and @sokrypton.org!

Expanding the scope of protein language modeling to protein-protein interactions with MSA Pairformer

Protein language models have excelled at modeling individual proteins, but extending these capabilities to protein complexes remains a major challenge. MSA Pairformer, a parameter-efficient protein la...

cell.com

Yours truly is a proper scientist now! TL;DR: we used AI to redesign parts of essential cell machinery with only 19 canonical amino acids instead of 20. Why? Great thread by @harriswang.bsky.social provides more context and details. Let me talk a bit about the AI design part of this. 1/

Harris Wang@harriswang.bsky.social · 3mo ago

1/ Excited to share our new paper in Science @science.org: “Toward life with a 19-amino acid alphabet through generative artificial intelligence design.” A great collab w/ Sergey's group @sokrypton.org at MIT @columbiasysbio.bsky.social science.org/doi/10.1126/... 🦠🧬🛠️🖥️💥

Big news! Starting my lab as Ramón y Cajal PI at @ibvf-sevilla.bsky.social in Seville 🌞, Spain, bridging microbial ecology, photosynthesis & plant biotech: from metagenomic and AI analyses 💻 to experiments in microbes & plants 🌊🧬🌱 Looking for PhD students & postdocs. DM or share!

research.arcadiascience.com/pub/resource...

Hot off the press, the most comprehensive survey ever performed of diatom distributions, abundances, and diversity in the global ocean. All enabled by the famous schooner@fondationtaraocean.bsky.social and lots of hard work from the Tara Oceans team! www.nature.com/articles/s41...

Patterns and drivers of diatom diversity and abundance in the global ocean - Nature Communications

Using the Tara Oceans dataset, this study describes global patterns of diatom diversity, abundance and adaptation. The authors identify 25 distinct communities, with the Arctic as a hotspot, and highl...

nature.com

Patterns and drivers of diatom diversity andabundance in the global ocean rdcu.be/ehlG4

NIH open source graphics bioart.niaid.nih.gov

doi.org/10.1101/2024...

Patterns and drivers of diatom diversity and abundance in the global ocean

Diatoms constitute one of the most diverse and ecologically important phytoplankton groups, yet their large-scale diversity patterns and drivers of abundance are unclear due to limited observations. H...

doi.org

Diatom phytochromes integrate the underwater light spectrum to sense depth www.nature.com/articles/s41...

Diatom phytochromes integrate the underwater light spectrum to sense depth - Nature

This study demonstrates that diatoms with phytochrome photoreceptors can detect and functionally respond to the entire visible light spectrum through these sensors, enabling them to sense depth a...

nature.com

Non-photosynthetic lineages sibling to Cyanobacteria associate with eukaryotes in the open ocean www.sciencedirect.com/science/arti... #jcampubs

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