📢 Don't miss out! 📢 Registration is now OPEN for our 3rd CSRP Conference 🎟️ Sign up today (for free!): bit.ly/44lOFAY or go to our website to learn more: bit.ly/4vUfurZ @capessuicideprev.bsky.social
Jordan Smoller
@jorsmo.bsky.social
Psychiatry, Genetics, Epidemiology, Precision Medicine. Author of The Other Side of Normal. 3% Neanderthal.
Free webinar: Hope you'll join us for this discussion of the important topic of grief and suicide loss.
We're excited to have a great speaker line up for our 6/17 talk! @samaritanshope.bsky.social #SuicidePrevention #SuicideResearch #GriefSupport #SuicideLossSurvivor Register for FREE today 👇👇 bit.ly/4myP4s4
New preprint! We investigate the risk of algorithmic bias (across race/ethnicity, gender, and their intersection) in machine learning models predicting suicide attempts across 3 clinical settings in over 1.2 million patients. osf.io/preprints/ps...
OSF
osf.io
Our multi-ancestry GWAS of EXTernalizing conditions (ADHD, substance use...) in ~4M people reveals neurodevelopmental risk, drug-repurposing targets, and yields one of the strongest psychiatric polygenic indices yet! 🧬🎉 doi.org/10.64898/202...
Genomic insights into substance use and disinhibitory disorders
Externalizing spectrum disorders- spanning attention-deficit/hyperactivity disorder, conduct disorder, substance use disorders, and other disorders characterized by disinhibition - frequently co-occur...
doi.org
4/4 A HUGE 🙏thank you to the @pgcgenetics.bsky.social working groups and participants and amazing co-authors, with special shoutout to Josefin Werme, Wouter Peyrot, Alex Frei, Christiaan de Leeuw, Lucy Bicks, Ken Kendler, and @jorsmo.bsky.social. This work reflects collaboration at its best ❤️🧬
Another great post from @sashagusevposts.bsky.social "The mystery of twin heritability comes to an ignoble end: no massive tranche of rare variants, no phantom interactions, just inflation." theinfinitesimal.substack.com/p/the-missin...
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
***3 days left to sign up for our virtual conference on Precision Psychiatry*** +CME +free for students and trainees. Featuring an amazing line-up of speakers.
New article written by Heather Stringer about precision treatment work in the mental health space by Kate Bentley, Ellen Driessen, @jorsmo.bsky.social, Leanne Williams, Conor Liston, and others www.apa.org/monitor/2025...
apa.org
Ending the federal LGBTQ+ suicide prevention line is a public health failure www.statnews.com/2025/07/12/e... via @statnews.com
Ending the federal LGBTQ+ suicide prevention line is a public health failure
Ending the federal LGBTQ+ suicide prevention line is a public health failure, write two leaders in prevention and crisis response.
statnews.com
The Surprising Scientists Hit by Trump’s D.E.I. Cuts www.nytimes.com/2025/07/10/u...
The Surprising Scientists Hit by Trump’s D.E.I. Cuts
nytimes.com
Twin study suggests genetic variation influences how funny you think you are but not how funny you actually are. 😄 www.cambridge.org/core/journal...
Heritability of Humor Production Ability — A Twin Study | Twin Research and Human Genetics | Cambridge Core
Heritability of Humor Production Ability — A Twin Study
cambridge.org
New polygenic score resource from Mykyta Artomov and colleagues and @finngen.bsky.social "All data and predictive tools are accessible via the PGS Browser (pgs.nchigm.org), an interactive web-based platform for PGS analysis and interpretation." www.medrxiv.org/content/10.1...
PGS Browser: a public platform for personalized polygenic score interpretation
Identifying individuals at elevated risk before disease onset is a cornerstone of personalized prevention, and polygenic scores (PGSs) have proven to be instrumental in this regard. In this study, we ...
medrxiv.org
"career staff were told not to respond in writing to panicky grant recipients whose funding had been shut off to avoid a “paper trail,” wapo.st/4kjmqsn
The first rule in Trump’s Washington: Don’t write anything down
A new culture of secrecy in government is taking root – among career staffers and new political appointees alike.
wapo.st
🆕📽️Last week's webinar is available now on YouTube! How to Help a Loved One Struggling with Suicidal Thoughts and Behaviors youtu.be/TMCAikdy2dQ?... Thank you to everyone who joined, our speakers, moderator, @jorsmo.bsky.social & @matnoc.bsky.social @afspnational.bsky.social
How to Help a Loved One Struggling with Suicidal Thoughts and Behaviors
YouTube video by Center for Suicide Research and Prevention (CSRP)
youtu.be
the disturbing old days of medicine and psychiatry in this episode of Medic from 1956: ulcerative colitis is caused by deep seated personality problems youtu.be/jki-rT92Uog
Medic - Season 2 - Episode 1 - All the Lonely Night | Richard Boone, Mary Stewart, Robert Stevenson
YouTube video by Classic TV Channel
youtu.be
From back in the day when a two page research paper with no tables or references could still be transformative?
Sad to see this. I used to love these numbers when I was a kid
Vince Vatter@vatter.bsky.social · last yr.interest in the natural numbers is at an all-time low
🚨🧬 New preprint! We tested whether PGS predicted global functioning across psychiatric hospitalization among 5991 people with schizophrenia. medrxiv.org/cgi/content/...
Polygenic Scores for Schizophrenia and Educational Attainment Predict Global Functioning Across Psychiatric Hospitalization Among People with Schizophrenia
Question Is variation in global functioning among people with schizophrenia associated with genetic differences? Findings In this genetic association study of 5991 adults with schizophrenia and 59,79...
medrxiv.org
New Forbes story about the economic consequences of science cuts. www.forbes.com/sites/johndr... Thoughtful and thorough analysis. 1/n
Trump’s NIH And NSF Cuts Estimated To Cost The U.S. Economy $10 Billion Annually
Economists find public R&D drives U.S. productivity growth — and pays for itself
forbes.com
Another breakthrough made possible by federal funding The result “is a triumph for the American peoples’ investment in biomedical research” Baby Is Healed With World’s First Personalized Gene-Editing Treatment www.nytimes.com/2025/05/15/h...
Baby Is Healed With World’s First Personalized Gene-Editing Treatment
nytimes.com
"let’s be clear: It isn’t institutions that are being punished. It’s the researchers who are the future of science in this country" What am I supposed to say to this generation of young scientists? www.statnews.com/2025/05/07/u... via @statnews.com
What am I supposed to say to this generation of young scientists?
Undermining the future of American science is not a path to accountability — it’s a path to decline.
statnews.com
75% of US scientists who answered Nature poll consider leaving www.nature.com/articles/d41...
75% of US scientists who answered Nature poll consider leaving
More than 1,600 readers answered our poll; many said they were looking for jobs in Europe and Canada.
nature.com
New work led by Yi-Han Sheu providing continuous-time and dynamic risk prediction models using Neuro-ODE with application to suicide risk prediction rdcu.be/eeIte
Continuous time and dynamic suicide attempt risk prediction with neural ordinary differential equations
npj Digital Medicine - Continuous time and dynamic suicide attempt risk prediction with neural ordinary differential equations
rdcu.be
JAMA 100 yrs ago: "it is generally recognized that men with large heads seem to represent the intelligentsia of man, although this does not mean necessarily that a smaller headed man may not be quite as keen in his intellectual processes." Large and Small Brains jamanetwork.com/journals/jam...
Large and Small Brains
Apparently, mankind is prejudiced in favor of heavy brained persons. This view was bluntly expressed at a recent conference by a physician who averred that it is generally recognized that men with lar...
jamanetwork.com
We Need a Reminder of What the Pre-Vaccine Era Was Like www.nytimes.com/interactive/...
Opinion | A Reminder of What Pre-Vaccine America Was Like
The worst manifestations of preventable diseases have faded from public memory.
nytimes.com