The ADVOCATE retraction isn’t necessarily the end of avacopan, it is the end of relying on evidence that can no longer be trusted. A retracted trial doesn’t prove a drug is ineffective. It means we need better evidence.
Jose Antonio Meade
@josemeade.bsky.social
PCCM fellow @mayoclinic.org - Interests include but not limited to #POCUS, meded and autoimmunity #RheumCrit 🩺⚕️
Bradykinin is an amazing molecule. Intersection between inflammation cascade, coagulation cascade, complement system AND RAAS system! Imagen generated with GPT.
Publication alert! 🚨 Does higher NSAID use increase the risk of incident hypertension in younger patients with newly diagnosed axSpA? Short answer: No. At least on the first 10 years of the disease course. kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F...
The success rate of “idk try an inotrope” has to be sub 5%* *even for intermediate physiologic outcomes
I am extremely grateful with @rheumcat.bsky.social for offering her time and mentorship with this project even before I started residency! It is a great clinical question with many implications and I learned many research skills from this!
Rheum Cat@rheumcat.bsky.social · 6mo agoNew publication led by @josemeade.bsky.social with @restovall.bsky.social authors.elsevier.com/sd/article/S... Does higher dose NSAID use increase risk of hypertension in younger adults with axial spondyloarthritis?
I asked ChatGPT to do a cartoon of my work based on everything it knows about me… the more you look at it, the more accurate it is!
Beta-blockers (BB) continue to lose terrain in different specific clinical scenarios. Sounds like this old question is finally answered… Use of BB after MI with normal EF: nejm.org/doi/full/10.10…
My research mentee matched to Mayo Clinic Pulm Crit!! Sooo happy for @josemeade.bsky.social, congrats!! #Fellowship #Match #MatchDay
📣 Calling all MD & DO students (including MD/PhD, DO/PhD, MD/MPH, DO/MPH)! Apply for the Rheumatology Future Physician Scientist Award, supporting research training for future physician-scientists in rheumatology. 🗓️ Applications due Dec 1, 2025 by 5 PM ET rheumresearch.org/preceptorships#RFPS
Abstract 1604: anti-rituximab antibodies as a cause of treatment failure in ANCA & cryoglobulinemic vasculitis. #ACR25
Dr. Martha Delgado gave a great #ACR25 presentation focused on improving patient participation in clinical trials in Latino communities. She shared barriers for both patients & providers as well current efforts to remove barriers. cc: @ladaorg.bsky.social #LADAorg @lupuschat.bsky.social #LupusChat
We wrote an article explaining why you shouldn't put several variables into a regression model and report which are statistically significant - even as exploratory research. bmjmedicine.bmj.com/content/4/1/.... How did we do?
Today, in collaboration with @BUMedicine Emergency Medicine, we shared some basic POCUS skills to our second-year medical students. Let’s keep integrating POCUS into medical school curricula!
This October I’m drawing 1 molecule a day inspired by proteins in pdb @rcsbpdb.bsky.social Day 13 Prompt DRINK Pdb: 7BTW A pair of mitochondrial outer membrane β-barrel SAM complexes from Saccharomyces cerevisiae, the yeast used to make beer. Cheers! Next: TRUNK Suggestions?
🧵 New study alert! 💊 Does early TNF inhibitor (TNFi) therapy reduce chronic opioid use in axial spondyloarthritis (axSpA)? 👉 We looked at real-world US data to find out. 📄 Arthritis Care & Research, 2025 🔗 acrjournals.onlinelibrary.wiley.com/doi/10.1002/... @rheumcat.bsky.social
Thanks for the head's up @restovall.bsky.social! Our mentee Jose Meade-Aguilar's work is cited from #ACR24 here: www.the-rheumatologist.org/article/key-...
Key Research in Axial Spondyloarthritis Encapsulated - The Rheumatologist
Our understanding of (axSpA) has really changed, especially with regard to male-female differences. In this report, we identify important research on axSpA presented at ACR Convergence 2024, summarize...
the-rheumatologist.org
NEW EPISODE! Alain Sanchez-Rodriguez, MD, joins the podcast to discuss delays in #lupus diagnosis & care based on findings from the Lupus Midwest Network (LUMEN) 🎙️Listen → https://acr.tw/3UWKCXi #Medsky
We had so much fun sharing some Lung POCUS basics to our MS2s @bumedicine.bsky.social! Their names is Ultrasound Is for Everyone and I just love it.
Thank you @rheumcat.bsky.social for many hours of outstanding mentoring and hard work! What an incredible journey this has been! @rheumresearch.bsky.social
