Confused by the 🚩on your patients CBC? A (pediatric) hematology primer -Thrombocytosis (high platelets) is reactive 99.9999% of the time. Think iron deficiency, infections. Hematologists rarely get excited until it’s multiple millions. 1/
Journal of Thrombosis and Haemostasis
@jthjournal.bsky.social
The Journal of Thrombosis and Haemostasis (JTH) is the official journal of the ISTH. The mission of JTH is to advance science related to the important medical problems of thrombosis, bleeding disorders and vascular biology. #MedSky #HemeSky #CardioSky
Overall, this review highlights the limited evidence supporting the use of anti-Xa monitoring for dose adjustments in the therapeutic use of low-molecular-weight heparins. Therefore, we conclude that measuring anti-Xa levels is currently not justified. @jthjournal.bsky.social
A systematic review on anti-Xa monitoring in the therapeutic use of low-molecular-weight heparins - PubMed
Low-molecular-weight heparins are widely utilized, including in special patient populations (eg, patients with renal impairment, pregnancy, and obesity). Monitoring with anti-Xa measurements is often used, but the effectiveness of anti-Xa-based dose adjustments remains uncertain. This systematic rev …
pubmed.ncbi.nlm.nih.gov
Check out the latest @jthjournal.bsky.social "JTH in Clinic" article providing clinicians w/real-world tools to manage gynecologic bleeding in patients on anticoagulation. Published in collab w/the Found. for Women & Girls w/Blood Disorders, it offers assess. & treatment guidance, bit.ly/4oOoD1N
New treatments have greatly improved survival for #cancer patients but they also come with a risk of #thrombosis. In our new review in @jthjournal.bsky.social we explain why. doi.org/10.1016/j.jt... @wardm6tcd.bsky.social @isth.org.
💡The @isth.org #SSC has been busy - dont miss the latest SSC ✅communications ✅guidance ✅guidelines published in @jthjournal.bsky.social : ℹ️https://bit.ly/4p1GYZz
Excited to share this article highlighting the important role of Antithrombosis Stewardship to improve Safe Transitions of Care in pts with VTE. #Stewardship #Anticoagulation #AntithromboticStewardship #TransitionsofCare @jthjournal.bsky.social @isth.org www.sciencedirect.com:5037/science/arti...
sciencedirect.com
🚨 New RPTH Journal Research Recap! Dive into the latest insights from recent articles. Read ahead: 📄 Full article → lnkd.in/eRJQcZEV 💬 Commentary → lnkd.in/g-q5ZvAa Register here: streamyard.com/watch/WB9QYXi3e3hH This Research Recap is supported by an educational grant from Takeda.
🚀 AI vs. Thrombosis Experts: Who performs better? New study shows: AI models deliver patient education answers that are often rated better than experts — and perform similar in complex clinical cases. @nikola-vladic.bsky.social @jeanconnorsmd.bsky.social @jthjournal.bsky.social
Large language models versus thrombosis experts: A comparative study on patient education and clinical decision-making in venous thromboembolism
Large language models (LLMs) have demonstrated remarkable capabilities in various medical fields, yet their performance in thrombosis and haemostasis, particularly in patient education and complex cli...
jthjournal.org
🤖🩸 #ArtificialIntelligence in everyday clinical practice: A study by #MedUniVienna shows that language models sometimes provide better answers than experts when it comes to questions about #venousthromboembolism. ⬇️ 📰 Results in @jthjournal.bsky.social
Artificial intelligence on a par with thrombosis experts
Learn more about the potential and limitations of language models in everyday clinical practice!
meduniwien.ac.at
ISTH is partnering with Inari, now a part of Stryker, for #WorldThrombosisDay 2025! Together we’re advancing #VTE care through a new educational offering: 🎧 The Role of Mechanical Thrombectomy in Transforming VTE Care Launching Oct 16 on the ISTH Pulse Podcast. 🔗 www.worldthrombosisday.org
JTH is proudly supports @worldthrombosisday.bsky.social! Show your commitment to patient safety and awareness this #WorldThrombosisDay on October 13. Share this graphic or create your own image using the WTD Design Hub: www.worldthrombosisday.org/poster-builder/ #WTDay25
The ISTH proudly recognizes Global #ITP Awareness Week 💜This year’s campaign theme, "Shining a light on ITP," underscores the importance of visibility and community engagement. #PaintThePlanetPurple #LightUp4ITP 🟣ISTH members: The ISTH offers educational resources about ITP here lnkd.in/debX39MC
1/ 📣 New risk calculator for stroke prediction in #AFib ♥️ Two #REGARDSStudy manuscripts in @jthjournal.bsky.social ♥️ One Identified biomarkers for breakthrough stroke ♥️ In the other we developed a new CHADS-VASc-Biomarkers score @samnotshort.bsky.social go.uvm.edu/strokecalc
New Risk Calculator Can Better Predict Stroke to Direct the Best Prevention | Office of Medical Communications | The University of Vermont
Researchers at the University of Vermont have developed a more precise way to assess stroke risk in people with atrial fibrillation (A-Fib), a condition that affects 10.5 million Americans and is a le...
go.uvm.edu
@jthjournal.bsky.social commentary in the most recent issue about more VTE prevention is needed in pregnancy - www.jthjournal.org/article/S153... It will be interesting to see what the new UK 37a green top guidelines advise in the Autumn
Venous thromboembolism in pregnancy: more prevention is needed
Pregnancy is a vulnerable period for the health of both mother and child. It is associated with a prothrombotic state, likely a part of an evolutionary development to protect against perinatal bleedin...
jthjournal.org
💡Turn your exciting research into high-impact publications! Whether you presented at #ISTH2025 &/or have some other new & exciting science to share, watch this interview w/our editors & learn more about submitting to @ISTH.org @jthjournal.bsky.social or @rpth.bsky.social bit.ly/46TLcfk
📢📢NEW research from @jthjournal.bsky.social! Two new papers were released on stroke risk and prediction in #atrialfibrillation. Whether you’re a clinician or researcher, you won’t want to miss these insights. Visit jthjournal.org to explore this new research. #stroke #afib #af
Our webinar with Dr. Jean M. Connors has been rescheduled to August 1st! Don’t miss this opportunity to hear from a top expert in the field! #ISTH2025 #Hematology #MedicalEducation #ClinicalHematology @ash.hematology.org @isth.org @jthjournal.bsky.social @athnnews.bsky.social
📚Spotlight on ISTH publications at #ISTH2025: ✅ @rpth.bsky.social: As ISTH’s open-access, online-only journal, RPTH is drives innovation & accessibility in science. ✅ @jthjournal.bsky.social: JTH publishes peer-reviewed groundbreaking research, reviews & clinical guidance Learn more: bit.ly/4k5PbID
Publications Spotlight: JTH & RPTH
ISTH Publications – Research and Practice in Thrombosis and Haemostasis (RPTH) Research and Practice in Thrombosis and Haemostasis (RPTH) is the open-access, online-only journal of the ISTH. Foll...
bit.ly
If you want to learn more about Factor XI inhibitors, check out this recent review article in @jthjournal.bsky.social pubmed.ncbi.nlm.nih.gov/39675564/
New targets for antithrombotic medications: seeking to decouple thrombosis from hemostasis - PubMed
Arterial and venous thromboses are the leading causes of morbidity and mortality worldwide. Numerous antithrombotic agents are currently available with antiplatelet, thrombolytic/fibrinolytic, and ant...
pubmed.ncbi.nlm.nih.gov
Global EHR-based study shows ~6% of children with CHD develop VTE within a year post-surgery, with a 25% recurrence rate. Most cases involved LE-DVT. Highlights need for targeted thromboprophylaxis strategies in this high-risk population. #PedsCardio #Thrombosis www.jthjournal.org/article/S153...
Amazing and thorough discussion on the ISTH Hemophilia Guidelines contents & methodology live at #ISTH2025 See this paper in JTHfor more deconstruction of the guidelines #hemophilia #hemesky www.jthjournal.org/article/S153...
Meta-analysis on GLP-1RA (vs. placebo) and VTE: 🔹 PE rates significantly lower 📉 🔹 VTE rates lower but not statistically significant 🔹 No difference in DVT 🔹 Study design matters: RCTs vs. observational data Accepted for publication in JTH! #ISTH2025 #VTE #GLP1RA #Thrombosis @jthjournal.bsky.social
The @rpth.bsky.social and @jthjournal.bsky.social Editors presented the Editors awards this afternoon, including this one to Daniel Steiner.
Corticosteroids remain the go-to for managing transaminitis post-valoctocogene roxaparvovec in hemophilia A. Early, reactive treatment may help preserve FVIII levels. #GeneTherapy #HemophiliaA #HemeSky www.jthjournal.org/article/S153...
Interesting discussion on high open access fees, increase of high quality papers from China & usage of Generative AI. More tools are needed #isth2025 @isth.org @jthjournal.bsky.social @rpth.bsky.social
More guidance on changing publishing landscape @researcheracad.bsky.social #isth2025
And we're off #isth2025 EIC Ton Lisman @jthjournal.bsky.social introduces key points! Follow them on @linkedin.com
Considerations for use of generative AI in publication presented at the Publication Session #ISTH2025 @jthjournal.bsky.social
Find the @rpth.bsky.social and @jthjournal.bsky.social editors in PUB01 - The evolving landscape of academic publishing! 📍Room 151 A&B ⏰ 10:30-11:30 🗣️ @profmakris.bsky.social, Ton Lisman and Suzanne Cannegieter with host Donna DiMichele
🩺 In the PAUSE-2 pilot trial, perioperative management of DOACs in patients undergoing high-bleed-risk surgery or neuraxial procedures was found feasible. Both ASRA- and PAUSE-based strategies achieved similar pre-op DOAC levels, supporting a larger trial. www.jthjournal.org/article/S153...
Just in time for the #ISTH2025 congress! @ISTH.org releases its Updated Clinical Practice Guidelines on the Diagnosis and Treatment of TTP. Learn more ⬇️and if you are attending #ISTH2025, don't miss the Guidelines Session GG01 on Saturday at 09:30 (US ET) bit.ly/3G8zaUp