Dr Satoshi Akima, FRACP

@toshiakima.bsky.social

Nephrology & Internal Medicine. Immunothrombosis incl DIC. ISTH Member. No Conflicts of Interest. Views my own etc

Platelet-activating antibodies against platelet factor 4 cause highly prothrombotic disorders with reduced platelet counts, including heparin-induced thrombocytopenia and vaccine-induced immune thrombocytopenia and thrombosis. Learn more: https://nej.md/4fskK0r

A bullet list of key points from the Review Article "Platelet-Activating Anti–Platelet Factor 4 Disorders" on a yellow background. The New England Journal of Medicine identity sits at the bottom.

I worked for New York’s largest medical center at the start of the pandemic. There were morgue trucks on the streets. They set up emergency medical tents in Central Park. Healthcare worker colleagues died. It is horrific that RFK Jr is on national TV lying that ICUs were empty.

7 mo into Covid-19 after grueling 24hr caring for child with the disease, who survived. Showered at hosp, returned to office & informed staff, wasn't retiring the next mo, as had planned. Photo of that moment. This is my "diary". Nobody can change the reality of pandemic for those who lived it...

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Studies are increasingly finding that bilingual people, who have native command of two languages, or multilinguals, who are able to speak more than two languages, are able to maintain their brains younger and healthier for longer. www.medicalnewstoday.com/articles/can...

Speaking several languages protects the aging brain: Here's how

Bilinguals and multilinguals may stay younger for longer and have more agile brains. This Special Feature shows just how language proficiency protects the brain.

medicalnewstoday.com

IL-6 also has anti-inflammatory and regenerative functions, despite its primary reputation as a classic pro-inflammatory acute-phase cytokine.  Classical signaling is associated with regenerative and anti-inflammatory functions, while trans-signaling is linked to pro-inflammatory functions

Swapnil Hiremath 🍁🇨🇦@hswapnil.medsky.social · 4d ago

ZEUS thunderbolt does not land uk.finance.yahoo.com/news/novo-no... Need to see full data at #KidneyWk - treating just inflammation likely doesn’t make sense

The decimation of our federal agencies has upended the lives of thousands of workers. These are the people who oversee food safety, public health, and much more. The squalor of this moment is bringing us back to basics — and reminding us of what our priorities should be. [Cartoon by Adam Zyglis]

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"Study uncovers molecular connections between COVID-19 and Pulmonary Arterial Hypertension (PAH)." COVID-19 can damage blood vessels in the lungs, causing inflammation. These changes resemble pulmonary arterial hypertension (PAH), a serious disease affecting the arteries that supply the lungs.

Study uncovers molecular connections between COVID-19, PAH

Researchers have identified shared molecular connections between COVID-19 and PAH that may explain common disease features, a study reports.

pulmonaryhypertensionnews.com

Among adults with #CKD due to glomerular diseases, finerenone slowed eGFR decline, reduced albuminuria, and lowered risk of kidney failure, with consistent benefits across disease subtypes and in those using #SGLT2 inhibitors. ja.ma/4fezkIJ

JAMA study: Finerenone for chronic kidney disease (glomerular). Conclusion: Finerenone slowed kidney function loss. Population: 903 adults (541M/362F, mean 51) from 24 countries. Finerenone group (446) eGFR slope -3.50, Placebo (457) -4.23 mL/min/1.73m²/year. Hazard ratio 0.74.