This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs. I believe last one is a 🕷️ #FluorescenceFriday #Microscopy
Júlia Garcia-Baucells
@jugarbau.bsky.social
Cell biologist driven by a passion for cell division
Really excited to see this out in the open: www.life-science-alliance.org/content/9/1/...! @isabellavoelkl.bsky.social explored and compared different in vitro developmental model systems to study ciliogenesis.
In vitro approaches to study centriole and cilium function in early mouse embryogenesis
Although centrioles and primary cilia play an essential role in early mammalian development, their specific function during the interval between their initial formation and the subsequent arrest of em...
life-science-alliance.org
See also:
Oliver W. Paulin, J\'ulia Garcia-Baucells, Luise Zieger, Sebastian Aland, Alexander Dammermann, David Zwicker: Active viscoelastic condensates provide controllable mechanical anchor points https://arxiv.org/abs/2506.14591 https://arxiv.org/pdf/2506.14591 https://arxiv.org/html/2506.14591
1/6 Extremely happy to share my PhD work is out on bioRxiv! We discovered that microtubules deform mitotic centrosomes. When we removed them, the SPD-5 scaffold became denser but didn't lose material. This suggests it's an elastically deformable solid! This only happens in mitosis.
Centrosome Softening As A Mechanical Adaptation For Mitosis https://www.biorxiv.org/content/10.1101/2025.09.09.675178v1
Wohoo new paper from the lab! @shiviyaraina.bsky.social
🆕 publication! What do centriolar satellites really do? In @jcb.org the Dammermann lab challenges the idea that they simply shuttle proteins to the centrosome and cilium. Instead, their findings reveal a surprising new role linked to translation and protein quality control. More tinyurl.com/4dnb2c24
Excited to share our discovery www.science.org/doi/10.1126/... that the #centrosome is prone to breakage! Using #motile cells, we identify centrosome breakage during #pathfinding, caused by #actin #forces, & prevented by #Dyrk3 Kudos to 1st author Madeleine & thanks to all collaborators! (1/6)
With Microscopy Nodes, you can play with large volumes (this ExM dataset from Granita Lokaj is 49 GB total) and integrate this with all the cool tools in Blender, such as this #geonodes model of the centriole, made by @banterlegroup.bsky.social !
Our first paper on BlueSky!! Remarkable work published in @currentbiology.bsky.social from Jing Xie, Javad Najafi and others, on how cell shape affects mitotic spindle positioning forces in embryos, by impacting cytoplasm flows. @ijmonod.bsky.social www.sciencedirect.com/science/arti...
#TeamTomo visits the centrosome. I remember the centrosome and PCM being one of Julia's first targets when we were postdocs together at @mpibiochem.bsky.social. It's cool seeing the progress here in worms with Jeff. Beautiful #CryoET across the cell cycle. @centriolelab.bsky.social take a look! 🧪🧶🧬
Mahamid and Woodruff labs use cryo-ET to look at mitotic centrosomes: Stunned to see the pericentriolar matrix taking shape, and what seem to be ‚S size’ gamma-tubulin complex oligomers capping the end of 11-pf microtubules. www.cell.com/developmenta...
Thank you Susana, Jadranka, Kevin and Jennifer for organizing these amazing sessions @ascbiology.bsky.social - so much exciting centrosome biology!!
We would like to thank all the speakers for their amazing and inspiring talks and all the attendees that made these sessions lively and engaging! We were so impressed with the younger investigators 🤩 the field has a bright future 👏👏👏
what if organelle interactions could be created and controlled synthetically? if you are at ASCB tomorow, check out the session "Toward Building In Vitro Organelle Interaction Systems" Saturday 9:30- 11:00 room 33B organized by @marymirvis.bsky.social Hanaa Hariri, and Gant Luxton.
Excited to join the #CellBio2024 to present our novel investigations into the mechanical properties of the centrosome on Tuesday. It’ll be a pleasure to discuss the details of my project with you!
Congrats to Claudia Pachinger PhD (Dammermann Lab), who recently defended her thesis: Novel insights into centriolar satellites as regulators of centrosome and cilium function. Well done! @univie.ac.at @impvienna.bsky.social @imbavienna.bsky.social @gmivienna.bsky.social @maxperutzlabs.bsky.social