Scientists at Gladstone and UCSF developed a method to genetically edit myeloid cells, immune cells that act as the body’s first responders. @ucsanfrancisco.bsky.social @juliacarnevale.bsky.social @marsonlab.bsky.social
New Toolkit Turns Macrophages Into Better Cancer Fighters
Gladstone and UCSF scientists developed a method to genetically edit myeloid cells, immune cells that act as the body's first responders.
gladstone.org
Another major milestone for my lab - our second paper is out today in Nature Biotechnology! Co-led by Pascal Devant & Hyuncheol Jung, with @marsonlab.bsky.social: www.nature.com/articles/s41...
Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells - Nature Biotechnology
Primary human myeloid cells are efficiently edited using virus-like particles.
nature.com
Very excited to share my lab's first major paper, led by postdoc Qi Liu @gladstoneinst.bsky.social @ucsanfrancisco.bsky.social executing the first ever genome-wide in vivo screens for genetic modifications to enhance human T cell therapies for solid tumors. www.nature.com/articles/s41...
In vivo genome-wide CRISPR screens of human T cells in solid tumours - Nature
An in vivo model that is able to recover human T cells from solid tumours can identify targets to help improve CAR T cell antitumour activity.
nature.com