Tim Doulton
@kentkidneydoc.bsky.social
Consultant kidney/BP doc East Kent | Co-lead KSS RDN for kidney disorders research | #NephSky | ❤️ NHS, 🎸, 🚴🏻 🌊 👨🍳 | Recent convert to open water 🏊🏻♂️| Hate inequality | Views my own
The Effect of SGLT2 Inhibitors aka #Flozins on Blood Pressure in Relation to Baseline Kidney Function: A Systematic Literature Review and Data Analysis 🔗 academic.oup.com/ajh/article-... 🔒
The Effect of SGLT2 Inhibitors on Blood Pressure in Relation to Baseline Kidney Function: A Systematic Literature Review and Data Analysis
AbstractBACKGROUND. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) reduce both systolic blood pressure (SBP) and diastolic blood pressure (DBP). The gl
academic.oup.com
I am delighted to see that @ukkidney.org has made the right call and exited X/Twitter.
Happy to contribute to this important statement @ahascience.bsky.social on cuffless devices led by @jordybc.bsky.social ! Cuffless Devices for the Measurement of Blood Pressure: A Scientific Statement From the American Heart Association | Hypertension ahajournals.org/doi/10.1161/...
The majority of doctors supported the recent strike. So why did the Department of Health suggest the opposite? www.theguardian.com/commentisfre...
The majority of doctors supported the recent strike. So why did the Department of Health suggest the opposite? | Peter Kellner
It would seem that poll data was cherrypicked and then used to brief the Times. Such distortion of facts from a public body should alarm us all, says former president of YouGov Peter Kellner
theguardian.com
www.theguardian.com/commentisfre...
Don’t believe Nigel Farage’s denials. He targeted me for being Jewish – and it hurt | Peter Ettedgui
Now that my former classmate has finally spoken about the allegations of his behaviour at school, I feel compelled to address his points directly, says Peter Ettedgui, a film director and producer
theguardian.com
The announcement of new asylum measures by the Home Secretary risks fuelling anti-migrant rhetoric. We reiterate our solidarity with our colleagues, many of whom are being subjected to increasingly hostile treatment as a direct result. www.bma.org.uk/news-and-opi...
@ukkidney.org guidelines for managing blood pressure in adults and CYP on dialysis is now published in BMC Nephrology 👏🏻 @profdg.bsky.social @hswapnil.medsky.social Find it here: link.springer.com/article/10.1...
Management of blood pressure in adults, children and young people on dialysis: UK kidney association clinical practice guideline - BMC Nephrology
People with end stage kidney disease receiving dialysis have a very risk of cardiovascular disease and mortality. Hypertension is a modifiable risk factor for cardiovascular disease and mortality, affecting around 90% of dialysis patients. Conversely, intradialytic hypotension in haemodialysis patients is associated with debilitating symptoms as well as the risk of cardiovascular disease and mortality. Blood pressure management in dialysis patients involves accurate measurement of blood pressure, setting a target blood pressure, adequate fluid volume management, lifestyle changes, modification of dialysis and dialysate, and the use of medication with proven efficacy in these patients. However, globally there is no published contemporary clinical practice guideline to assist health care professionals to manage blood pressure in dialysis patients. This is mainly because of a dearth of good quality evidence to inform guideline recommendations. Here, we present a comprehensive guideline to manage blood pressure in dialysis patients based on a thorough systematic review of literature. The guideline development committee comprised a multidisciplinary group of nephrology healthcare professionals and a patient. The evidence underpinning the guidance is often of moderate to low quality, influencing the strength of the recommendations. Therefore, the committee have come up with a list of research recommendations with a view to informing future guidelines. It is envisaged that this guideline will improve the care and outcomes of dialysis patients in the UK and elsewhere.
link.springer.com
Proud to have worked with colleagues and friends around the world on #ACHIEVE. We're disappointed spiro didn't prevent CV death/heart failure hospitalizations, but we've shown it's possible to do publicly funded large RCTs of repurposed meds in ESKD. More to do! www.sciencedirect.com/science/arti...
Spironolactone versus placebo in patients undergoing maintenance dialysis (ACHIEVE): an international, parallel-group, randomised controlled trial
Patients undergoing maintenance dialysis for kidney failure are at substantial risk of cardiovascular morbidity and mortality. We aimed to establish i…
sciencedirect.com
www.theguardian.com/business/202... From someone who has been PI on multiple clinical trials in people with kidney disease this is deeply concerning … @rthonwesstreeting.bsky.social
Britain is ‘a terrible place’ to sell medicines, says drug firm executive
Sanofi’s market access chief urges ministers to come up with a roadmap to raise spending on new treatments
theguardian.com
Unlike Radiohead it doesn’t look like the Smiths will be touring again anytime soon 😢 www.theguardian.com/music/2025/s...
Morrissey puts his business interests in the Smiths up for sale ‘to any interested party’
Musician says he has ‘no choice’ after being ‘burnt out by any and all connections’ to his former bandmates
theguardian.com
bihs.org.uk/news/21/prof... Graham was my boss and MD supervisor at St George’s, University of London. He started me on a journey that continues to this day. Our East Kent Hypertension Clinic is part of Graham’s legacy. A giant in nephrology and CV medicine 🙏🏻
Professor Graham A MacGregor (1941-2025)
bihs.org.uk
18km continuous ascent to Col de la Colombière with my mate Bryan over the summer 🥵
Nephrology community take note 👇 #nephsky @bmj.com Risks of assuming homogenous effects of ancillary treatment in heterogenous healthcare systems in global RCTs www.bmj.com/content/389/...
Rethinking approaches to analysis of global randomised controlled trials
Choice of statistical models and data integrity are vital A BMJ investigation by Doshi (doi:10.1136/bmj.r1201)1raises concerns about the integrity of two randomised trials with surrogate endpoints th...
bmj.com
@ukkidney.org #UKKW25 Prof David Wheeler and one of my fave slides reminding us how nephrologists weren’t so good at RCTs 🤣 but how times have changed … 1/2
💪 PD lets patients manage care at home, maintaining hope as they wait. 👥 We honor recipients, donors, and all who navigate this path with strength. PD supports this journey. #WorldTransplantDay #PeritonealDialysis #TransplantDay
🌱 Today is #TransplantDay, celebrating organ donors' life-saving gift. At ISPD, we emphasize the journey before that crucial call. 🫘 #PeritonealDialysis (PD) is more than a treatment; it's a vital bridge offering freedom and quality of life for those awaiting a transplant. #WorldTransplantDay
Most comprehensive clinical practice guideline on the management of hypertension in dialysis patients - first-of-its-kind globally - based on extensive systematic literature review
UK Kidney Association@ukkidney.org · last yr.✨New first-of-its-kind guideline on managing blood pressure in adults, children & young people on dialysis. The important guidance covers BP targets, treatment & lifestyle approaches to improve care. 📰News story: ow.ly/VjO650ViYlz Full Guideline: ow.ly/tocb50ViYly
How about the siRNA (hot off the press from yesterday's @jama.com ) Zilebesiran summary evidence @drjmluther.bsky.social at @hypertensioncanada.bsky.social #CHC25
Thanks @ukkidney.org for my 🎁 … I’ve always hankered after a sprung-loaded self-retracting lanyard (such a thing must have a specific name 🤣)
“Science has no passport, no gender, no ethnicity, no political party.” EC President Ursula von der Leyen, announcing a €500M initiative to attract top global talent. In a fractured world, science remains a unifying force – rooted in diversity, driven by curiosity, and shared by all humanity.
Remarkable conduct from the GMC. The Leng Review is currently investigating whether PAs are safe seeing patients. Yet here's the GMC steaming ahead will rolling out 1000s more PAs, in the face of fierce opposition from doctors with major safety concerns. www.theguardian.com/education/20...
GMC approves 36 courses to teach more than 1,000 NHS physician associates
New accreditation for PAs and anaesthesia associates is ‘important milestone’ for patient assurance, regulator says
theguardian.com