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Krzysztof Kiryluk

@kirylukk.bsky.social

Medicine, Genetics, Statistics, Kidney Disease, Columbia University. My posts represent my own views and not those of Columbia University.

31 Posts416 Follower 243 Folgt

Krzysztof Kiryluk @kirylukk.bsky.social · 3mo ago

New work from our lab enabling scalable detection and staging of acute kidney injury from electronic health records. Many potential applications to genetic and epi studies of kidney disease across EHR-linked biobanks! Please check it out... @ajkd.bsky.social

American Journal of Kidney Diseases@ajkd.bsky.social · 3mo ago

Electronic Phenotype for Detection, Staging, and Subtyping of Acute Kidney Injury bit.ly/4beAGRi (OPEN ACCESS)

Krzysztof Kiryluk @kirylukk.bsky.social · 7mo ago

COMPLIMENTARY VIRTUAL PROGRAM: IgA Nephropathy 2026 Diagnosis & Treatment Updates - Friday, April 10, 2026 - 4.50 ACCME Credits Available www.eventleaf.com/e/IGAN2026

Krzysztof Kiryluk @kirylukk.bsky.social · 9mo ago

Registration NOW Open for 'The 49th Annual Columbia Renal Biopsy Course’ - July 15-17, 2026 - an in-person & virtual program with ACCME credits & video access. Click for agenda, full details & registration: www.eventleaf.com/e/RenalBiops...

The Columbia Renal Biopsy Course - 49th Annual

23.25 ACCME Credits, In-Person & Virtual Conference

eventleaf.com

Kidney International @kidneyint.bsky.social · 12mo ago

Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function doi.org/10.1016/j.kint.2025.08.0 #OpenAccess #MedSky #NephSky #kidneydisease #GWAS @uniklinik-fr.bsky.social @columbiakidney.bsky.social @columbiauniversity.bsky.social @kirylukk.bsky.social

Krzysztof Kiryluk @kirylukk.bsky.social · last yr.

Join us for ‘#LUPUS: Current & Future Breakthroughs’ – a virtual and in-person conference on Friday, September 12, 2025 with 7.50 ACCME Credits. Registration & info: www.eventleaf.com/e/Lupus2025 #lupus #arthritis #Nephritis #CARTcell #autoimmune #autoimmunedisease #rheumatology #MedEd

Krzysztof Kiryluk @kirylukk.bsky.social · last yr.

www.nytimes.com/2025/06/09/h...

N.I.H. Workers Denounce Trump’s ‘Harmful’ Health Policies

nytimes.com

Krzysztof Kiryluk @kirylukk.bsky.social · last yr.

The Gutting of America’s Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant www.nytimes.com/interactive/...

Here Are the Nearly 2,500 Medical Research Grants Canceled or Delayed by Trump

Some cuts have been starkly visible, but the country’s medical grant-making machinery has also radically transformed outside the public eye.

nytimes.com

Eric Topol @erictopol.bsky.social · last yr.

www.economist.com/leaders/2025...

The American Society for Clinical Investigation @the-asci.org · last yr.

Uncovering the pathogenesis in glomerulonephritis— ASCI member Ali G. Gharavi & team discover GALNT14 variants in patients with IgA nephropathy that link O-glycosylation defects with altered mucosal immunity and B cell homing: buff.ly/Q8zdWgy

Krzysztof Kiryluk @kirylukk.bsky.social · last yr.

Trump Has Cut Science Funding to Its Lowest Level in Decades www.nytimes.com/interactive/...

Trump Has Cut Science Funding to Its Lowest Level in Decades

The lag in funding extends far beyond D.E.I. initiatives, affecting almost every area of science: chemistry, computing, engineering, materials and more.

nytimes.com

Krzysztof Kiryluk @kirylukk.bsky.social · last yr.

This is a disaster on multiple levels. The litany of bad ideas continues to flow freely...

Nature@nature.com · last yr.

A forthcoming policy from the US National Institutes of Health (NIH) will target — and at least temporarily stop — funding to laboratories and hospitals outside the United States. https://go.nature.com/4cXQpnA

Gregg Gonsalves @gregggonsalves.bsky.social · last yr.

I am late to this but @lastweektonight.com is doing better journalism on the Trump-induced crisis in American public health than most other "real" mainstream media outlets. Watch it, all of it. #RFKMustGo. youtu.be/8H34jcpEsFs?...

RFK Jr. & HHS: Last Week Tonight with John Oliver (HBO)

YouTube video by LastWeekTonight

youtu.be

The Lancet @thelancet.com · last yr.

🆕 “Science and medicine in the USA are being violently dismembered while the world watches [...] bullies are only emboldened by acquiescence or indifference.” The Lancet’s latest Editorial: Supporting medical science in the USA www.thelancet.com/journals/lan...

Nature @nature.com · last yr.

Fresh turmoil has hit the US National Science Foundation: hundreds more of the agency’s research grants were terminated today on top of the hundreds already terminated last week, Nature has learnt. https://go.nature.com/3YOHqiq

Hundreds more NSF grants terminated after agency director resigns

Sethuraman Panchanathan abruptly leaves helm of US funding agency after Elon Musk’s DOGE arrives.

go.nature.com

Molly Przeworski @mollyprz.bsky.social · last yr.

Posting on behalf of Shamil Sunyaev: Eimear(Vice Chair) and I (Chair) are organizing the 2025 Gordon Research Conference (GRC) on Human Genetics and Genomics, which will be held on July 6-11, 2025 in beautiful University of Southern Maine, Portland, Maine.

2025 Human Genetics and Genomics Conference GRC

The 2025 Gordon Research Conference on Human Genetics and Genomics will be held in Portland, Maine. Apply today to reserve your spot.

grc.org

The New Yorker @newyorker.com · last yr.

The Trump Administration’s cuts at Health and Human Services hit every part of the scientific establishment: not only the federal government and universities but also states, counties, cities, and the private sector.

“I Am Seeing My Community of Researchers Decimated”

Across the country, the Trump Administration’s assault on public institutions and its cuts to government funding are forcing scientists to abandon their work and the patients who benefit from it.

nyer.cm

Swapnil Hiremath 🍁🇨🇦@hswapnil.medsky.social · last yr.

The ASIs have arrived www.nejm.org/doi/full/10.... Aldosterone synthase inhibitors - first one to finish the phase 3 line #Lorundrostat #Hypertension

Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension | NEJM

Aldosterone dysregulation contributes to hypertension. Lorundrostat is an aldosterone synthase inhibitor, but data on its efficacy and safety in patients with hypertension are limited. In this mult...

nejm.org

Krzysztof Kiryluk @kirylukk.bsky.social · last yr.

Good for Harvard. Hope Columbia will do the same! www.nytimes.com/2025/04/21/u...

Harvard Sues Trump Administration Over Threats to Cut Funding

Harvard’s lawsuit comes after the administration sought to force the university to comply with a list of demands by cutting billions in federal funding the school receives.

nytimes.com

Krzysztof Kiryluk @kirylukk.bsky.social · last yr.

Another twist to the story, and a shocking display of the administration's utter incompetence: Trump Officials Blame Mistake for Setting Off Confrontation With Harvard www.nytimes.com/2025/04/18/b...

Trump Officials Blame Mistake for Setting Off Confrontation With Harvard

An official on the administration’s antisemitism task force told the university that a letter of demands had been sent without authorization.

nytimes.com

Carl T. Bergstrom @carlbergstrom.com · last yr.

Meanwhile, DOJ lawyers are threatening medical journals for not providing adequate "viewpoint diversity" and for misinforming their readership, which I suppose means not publishing enough of the stupid shit that RFK Jr., JB, etc. keep saying. This is an outrageous First Amendment violation.

Medical Journals Get Letters From DOJ

At least three journals received letters from a U.S. Attorney asking about 'competing viewpoints'

medpagetoday.com

Krzysztof Kiryluk @kirylukk.bsky.social · last yr.

Despicable AND dishonest.

Science Magazine@science.org · last yr.

After freezing all grants to Columbia University last week, the National Institutes of Health is now stopping grant and contract payments to Harvard University and four other universities. scim.ag/4ikYp2T

The New Yorker @newyorker.com · last yr.

Universities, which are defined by academic independence yet depend on government support, are extremely vulnerable to government bullying. Harvard’s decision suggests that some, at least, have a limit to how far they’re willing to be pushed.

Why Harvard Decided to Challenge Donald Trump

Universities are accustomed to acquiescing to the government, but Trump made Harvard an offer it couldn’t not refuse.

newyorker.com

Krzysztof Kiryluk @kirylukk.bsky.social · 2y ago

Great points and my favorite quote of the day "If you hire clowns, you should expect a circus." What Trump Just Cost America www.nytimes.com/2025/04/09/o...

Opinion | What Trump Just Cost America

Do you think these former close U.S. allies are ever going to trust getting into a trench with this administration again?

nytimes.com

Sasha Gusev @sashagusevposts.bsky.social · 2y ago

In light of HHS freezing all research funds to Columbia today, I think this op-ed from Larry Summers last week is worth revisiting. Universities should: - Negotiate only over matters covered by statute - Leverage endowments - Implement their own reforms archive.is/KL3Dd

$President Trump offered praise to a white-supremacist rally that included chants of “Jews will not replace us,” publicly dined with Holocaust deniers, made common cause with Germany’s Nazi-descendant AfD party and invoked tropes about wealthy Jews. The true motivation behind his attack on universities is suggested by Vice President JD Vance’s declaration that the “universities are the enemy.” Shakedown is the administration’s strategy as it has gone after law firms, federal judges, legislators who disagree with its edicts and traditionally independent arms of the government. Title VI of the 1964 Civil Rights Act appropriately allows that federal funding of universities can be made contingent on their avoiding discrimination. But as a recent statement by a group of leading law professors points out, it also protects against this power’s being used to punish critics or curtail academic freedom. Among the law’s requirements are notice periods, hearings, remedies that are narrowly tailored to specific infractions and a 30-day congressional notification before any funding is curtailed. None of this appears to be part of the Trump administration’s approach to universities.$

Universities facing those threats should make clear they are willing to negotiate with government officials only over matters covered by statute and through the procedures laid out in the law.

They should make clear that their formidable financial endowments are not there to simply be envied or admired. Part of their function is to be drawn down in the face of emergencies, and covering federal funding lapses surely counts as one. As a former president of Harvard University, believe me when I say that ways can be found in an emergency to deploy even parts of the endowment that have been earmarked for specific use by their donors.

And to maintain the moral high ground, which universities have in large part lost, they need a much more aggressive reform agenda focused on antisemitism, celebrating excellence rather than venerating identity, pursuing truth rather than particular notions of social justice and promoting diversity of perspective as the most important dimension of diversity.

Krzysztof Kiryluk @kirylukk.bsky.social · 2y ago

Nice to see this - hope all other major Universities take the same stance.

A. Susana Ramírez, PhD, MPH@susanaramirez.bsky.social · 2y ago

Proud to be part of the UC At a special meeting today, the Academic Council unanimously endorsed The Defense of the University, a statement reaffirming UC’s public mission amid growing national threats to higher education. #HigherEd #AcademicSky #AcademicFreedom

Screenshot of text document on UC Academic Senate letterhead: Academic Council Statement: The Defense of the University
April 8, 2025
Higher education is under direct and sustained attack. Deliberate and systemic shifts in the federal government’s approach to higher education—which include defunding crucial research, intervening in academic affairs, and policing expression—will have profound downstream consequences, threatening the integrity of knowledge production and the public role of universities in a democratic society. The mission of the University of California is thus existentially at risk.
Unity will be critical in the weeks, months, and years ahead, as the University of California fights to preserve its capacity to prepare the next generation of the workforce. These graduates will be leading health care providers, educators, authors, entrepreneurs, and innovators. Given the opportunity, they will conduct the research leading to breakthroughs in science and technology, new treatments for disease, new forms of creative expression, and new insights about the world we inhabit. Let us remember that our university played a foundational role in the development of the Internet, satellite communications, nuclear energy, biotechnology, agronomy, and many other domains that have substantially improved our collective well-being. If our research and teaching mission is compromised, what future discoveries will be lost, and at what cost to the public health
and welfare of all Californians?

The Academic Senate is one of the pillars of shared governance of the University of California, along with the Regents and the administration. Policies and practices of shared governance have served the institution well during previous crises, and we will have even greater need of them as we move forward. The urgency and complexity of the problems we confront necessitate collaborative efforts. We need to stand, speak, and work together—informed by our shared, fundamental principles—i…

Krzysztof Kiryluk @kirylukk.bsky.social · 2y ago

Picture of the day.

Krzysztof Kiryluk @kirylukk.bsky.social · 2y ago

I am feeling much less anxious about the climate change already… www.nytimes.com/2025/04/09/c...

Trump Administration Cuts Princeton Funding to Study Climate Change

The cuts to a Princeton University program come as the Trump administration has been reviewing an array of research grants related to global warming.

nytimes.com

Krzysztof Kiryluk @kirylukk.bsky.social · 2y ago

The damage to the medical school and health sciences will be irreversible. NIH freezes all research grants to Columbia University | Science | AAAS www.science.org/content/arti...

NIH freezes all research grants to Columbia University

Amid negotiations with Trump, the university could risk losing nearly $700 million

science.org

Krzysztof Kiryluk @kirylukk.bsky.social · 2y ago

Finally, top scientists speak up against the Trump administration in a letter signed by 2,000 elected members of the National Academies of Sciences, Engineering, and Medicine: "the nation's scientific enterprise is being decimated"; see related NYT coverage here: www.nytimes.com/2025/03/31/s...

Krzysztof Kiryluk @kirylukk.bsky.social · 2y ago

Columbia's annual "IgA Nephropathy 2025 Diagnosis & Treatment Updates" CME course coming up on April 4th. Join us for a great day packed with the latest data: complement inhibition, B-cell therapies, SGLT2i, DEARA, and more... @cuimcmedicinedept.bsky.social @columbiakidney.bsky.social