New in PLOS Pathogens 🎉 How does OM-89 (Uro-Vaxom) protect against recurrent UTIs? 🦠 Our paper: it activates lysosomes in bladder epithelial cells, pushing intracellular E. coli into acidic, protease-active compartments and improving antibiotic killing. 🧵 10.1371/journal.ppat.1014448 #UTISky #UPEC

Very happy to see our microphysiological human mini-bladder published! 🎉 We show how urine composition affects tissue health and thus invasivness of UPEC, and how cell wall-deficient UPEC from the tissue reactive UTIs. 🦠 Check it out here: www.nature.com/articles/s41... #UTISky

New paper in Applied and Environmental Microbiology! 📢 Under the lead of Pablo Molina, we introduce SimUrine, a fully defined synthetic urine medium for growth and antibiotic susceptibility testing of uropathogens under physiologically relevant conditions 🦠 journals.asm.org/doi/10.1128/... #UTISky

👉 Host-targeted immunity meets antibiotic synergy! We show that OM-89 reprograms bladder epithelial cells to boost their lysosomal activity and antibiotic uptake, helping clear intracellular UPEC. 📖 Read more: www.biorxiv.org/content/10.1... #UTI #InfectiousDisease #HostDefense #Organoids #UTIsky

Almost 4 days of learning about teaching and mentoring. What an intense experience! Was it a lot? Yes. Was it fun? Oh yes! I learned more than expected. As scientist we have the responsibility to train the next generation. Let's do it the best possible way. 🤓 #teaching #workshops #EPFL #learning

Had a blast at the New Approaches and Concepts in Microbiology Symposiums this week 🦠 Indeed my favorite meeting and even more so when I meet old and new friends! Not to forget to mention the party 😎 #EESMicrobiology @EMBLEvents

We are recruiting a tenure-track assistant professor in molecular microbiology in our department in Lausanne! Do consider appyling!!

DMF UNIL@dmf-unil.bsky.social · last yr.

Come join us in beautiful Lausanne! Deadline for applications: August 10th, 2025 wwwfbm.unil.ch/releve/appli...

It's a wrap! Incredible science, people and discussions at the "New challenges in Microbial Eco-Evolutionary Medicine" workshop. Thank you @lizscurious.bsky.social for the invitation. It was a pleasure to talk about our research on recurrent #UTI using #organoids and collaboration with OM pharma.

Another PhD opportunity to join the growing Microbiology community in Southampton 💪 🦠 🔬 Interested in how bacteria adapt to challenges like temperature changes and antibiotics? Join my lab at UoS to explore the role of accessory elements! tinyurl.com/PhDbacteriaUoS Apply here: tinyurl.com/MicroUoS

Accessory Genomes and Evolutionary Strategies of Antibiotic-Resistant Bacteria at University of Southampton on FindAPhD.com

PhD Project - Accessory Genomes and Evolutionary Strategies of Antibiotic-Resistant Bacteria at University of Southampton, listed on FindAPhD.com

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Being a woman in science can be challenging for many reasons. Having a supportive network (family, friends, mentors) is essential! If you want to go into STEM, go for it and find yourself a mentor. Female scientists are usually more than happy to share their experiences💚 youtube.com/shorts/9XnOb...

Women's Day Interviews 2025

YouTube video by EPFL School of Life Sciences

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The Image & Optics Facility @ Institute of Science and Technology Austria is expanding it’s image analysis services and has a vacant position for a service oriented *Image Analysis Specialist* with a strong interest for data infrastructure organization🔬🧑‍💻📈 - sharing is much appreciated!

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Job details

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We found that many bacterial species use exogenous peptidoglycan fragments - released by lysis of neighboring cells - as a general danger signal, triggering a danger response that protects bacteria against many dangers: biofilm formation. Details here 👇 www.nature.com/articles/s41...

Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation - Nature Microbiology

Peptidoglycan released by neighbouring kin or non-kin cell lysis induces physiological changes that protect from a range of stresses, including phage predation.

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A simple ex vivo bladder infection model permits study of host-pathogen interactions in UTI ✍️Rixa-Mareike Köhn, Molly A Ingersoll and colleagues @institutcochin.bsky.social @pasteur.fr @aimi-uts.bsky.social #MicroSky #Infection #UTI www.biorxiv.org/content/10.1...

Had a great time at the first ever Klebsiella meeting taking place in Paris the past days. Lots of information and great science to digest for a non-Klebsiella person. We even had the first snow since years in Paris ❄️ #Klebs2024