Exclusive: Death of girl in Chinese gene-editing trial was never made public

Parents want accountability after study went disastrously wrong, Science and Retraction Watch investigation reveals

science.org

How should I respond to race-based exclusion in my lab?

A researcher in Europe feels left out of their team and held to different standards from their colleagues. How can they challenge exclusion without risking their position?

go.nature.com

Attention modulates value normalization in human reinforcement learning by shaping reward encoding - Nature Communications

People’s reward learning is shaped by context, but the cognitive origins of this bias remain poorly understood. Here, the authors provide evidence that attention may underlie these distortions by shap...

nature.com

Information normally considered task-irrelevant drives decision-making and affects premotor circuit recruitment - Nature Communications

Prior experience is used by the brain to guide adaptive behaviour during decision making. Here, the authors show that mice also selectively use information learned through recent and longer-term exper...

nature.com

Learned statistical regularity modulates anticipatory micro-saccades toward suppressed distractor locations - Nature Communications

Statistical learning guide attention by shaping anticipatory oculomotor behavior. Here, the authors show that microsaccades are biased to expected distractor locations before stimulus onset and predic...

nature.com

Sensorimotor transformation of number in the primate parietal cortex - Nature Communications

How the brain transforms perceived number into corresponding numbers of self-generated actions is unknown. Here, the authors show that neurons in primate ventral intraparietal area are tuned to the nu...

nature.com

Reward magnitude determines reinforcement learning efficiency

Standard animal learning studies minimize individual reward magnitudes to maximize the repetitions of reinforced behaviors. We investigated how reward magnitude influences initial learning across five...

science.org

Neural Dynamics of Belief and Value Computations Guiding Strategic Social Decisions

Successful strategic behavior must be grounded in beliefs about the opponent and her intentions. While many potential models have been proposed to explain choices in such situations, the neural mechanisms that govern learning and choice in complex strategic contexts remain poorly understood. Here, we use a computational model that combines dynamic learning and choice mechanisms to explain both choices and response times of human participants engaged in a competitive strategic task. Using electroencephalography (EEG), we identify temporally structured stages of neural processing that support an evolving value-based decision process, corresponding to first- and second-order belief updates and evidence accumulation related to the comparison of action values. Gamma-band phase coupling between central and parietal EEG signals varied with individual winning rate, suggesting that strategic behavior involves coordinated information transfer across spatially remote areas. Together, our data characterize the temporally evolving neural dynamics of belief and valuation processes that underlie strategic choice and provide neural validation for assumptions embedded in computational models of this behavior. ### Competing Interest Statement The authors have declared no competing interest. European Research Council, 725355

biorxiv.org

Motor equivalence in motor awareness

Psychology

cell.com

Neuroscience undermines the higher-order theorists’ preferred solution to the targetless HOT problem

The Higher-Order Theory (HOT) of consciousness holds that mental states become conscious when they are represented by another mental state. Most HOT theorists maintain that it is the higher-order, ...

doi.org

Learning realistic lip motions for humanoid face robots

We propose a self-supervised facial action transformer that enables multilingual lip synchronization in humanoid robots.

science.org

Hierarchical interactions between sensory cortices defy predictive coding

Perceptual experience depends on recurrent interactions between lower and higher cortices. One theory, predictive coding, posits that feedback from higher to lower brain regions decreases neuronal activity predicted by higher-level representations. Despite the widespread adoption of predictive coding in neuroscience, the correspondence to neurophysiological findings in sensory cortices remains elusive. Here, we review how the canonical patterns of intra- and inter-cortical interactions that occur during perception and shifts of attention deviate from those predicted by predictive coding. We argue that these circuit interactions are better captured by alternative theories, which we summarize under the umbrella term BELIEF. We review how BELIEF theories account for the inter-areal interactions during attentive perception.

dlvr.it

Correlation detection as a stimulus computable account for audiovisual perception, causal inference, and saliency maps in mammals

Optimal cue integration, Bayesian Causal Inference, spatial orienting, speech illusions and other key phenomena in audiovisual perception naturally emerge from the collective behavior of a population ...

elifesciences.org

The spatiotemporal structure of neural activity in motor cortex during reaching

Intracortical brain-computer interfaces (BCI) leverage knowledge about neural representations to translate movement-related neural activity into actions. BCI implants have targeted broad cortical regi...

biorxiv.org

Sensory reformatting for a working visual memory

A core function of visual working memory (WM) is to sustain mental representations of recent visual inputs, thereby bridging moments of experience. This is thought to occur in part by recruiting early...

cell.com

Arousal as a universal embedding for spatiotemporal brain dynamics - Nature

Reframing of arousal as a latent dynamical system can reconstruct multidimensional measurements of large-scale spatiotemporal brain dynamics on the timescale of seconds in mice.

nature.com

Mirror manifolds: partially overlapping neural subspaces for speaking and listening

Participants in conversations need to associate words their speakers but also retain those words general meanings. For example, someone talking about their hand is not referring to the other speakers ...

biorxiv.org