Kyle Cottrell
@kylecottrell.bsky.social
Father | Assistant Professor @PurdueBiochem (RNA editing and regulation) | Postdoc & PhD @WUSTL | MS & BS @MissouriState | #firstgen #NewPI #NIHMOSAIC K99/R00 (posts and comments are my own and do not reflect my employer)
Switch to natives and you get beautiful blooms and pollinators.
Mother Jones@motherjones.com · 3mo agoFor decades, native plants couldn't be given away. Now a Chicago park sale that normally draws 1,100 people drew 2,300 this year—and sold out completely. "It's not a fad," says one nurseryman who's watched the trend for 44 years. "This is a long, steady climb."
This week the lab said goodbye to three undergraduate researchers. Estelle was the first person to join the lab. Renee and Madison joined not long after. Each have made important contributions leading to authorships. They are now off to dental, medical and graduate school! We will miss them greatly.
Today is the day! Our first Purdue RNA Club Symposium. Thanks to support from @rnasociety.bsky.social and #Lexogen.
I’m super excited to be opening a lab at WEHI. We’ll be focussing on how double-stranded RNA is regulated in cells, how failures in these pathways drive disease and new therapies to manipulate inflammatory responses to RNA. #newPI #RNAsky
WEHI (The Walter and Eliza Hall Institute of Medical Research)@wehi-research.bsky.social · 7mo agoSay hello to our incoming lab heads! 👋 Excited to announce Dr Danika Hill, Dr Jacki Heraud-Farlow and Dr Sylvie Callegari will soon be establishing new labs at WEHI. More info: www.wehi.edu.au/news/excepti... bsky.app/profile/sylv... bsky.app/profile/jack... bsky.app/profile/prec...
I wonder who gets spots in the Purdue summer camp before us plebs gets our chance to register? Must be nice to have a guaranteed spot and not have to block out your morning and stress over getting a good spot in the registration queue.
Some us, not very many, started at community college and never took the ACT or SAT...
Jonathan Rosenblum@jsrosenblum.bsky.social · 8mo agoWhich links to this proposed Act, which says "...requiring all parts of a state university system to publish every higher-education standardized test score (SAT, ACT, CRT, GRE, LSAT, MCAT, etc.) of every faculty member..." and every applicant. So it's super dumb, but not "SAT but not GRE."
Per tradition, the house has been built. Decorations tomorrow!
Done with the last lecture of the year! Looking forward to the next ~9 months of bench work.
New addition this year was homemade cranberry sauce. Don't know why I waited this long to do that on.
We start the module on nerve gasses in my course today - queue Nick Cage!
a man is kneeling down with his arms outstretched in front of a body of water with a bridge in the background
ALT: a man is kneeling down with his arms outstretched in front of a body of water with a bridge in the background
media.tenor.com
RNA Club returns on Friday with Iman Mevaa from the @kasinskilab.bsky.social presenting a talk titled Targeted Delivery of Tumor-Suppressive miR-34a for Osteosarcoma Treatment. We will meet in ABE B061 at 3:30 on October 10.
My first trip out of the Purdue Airport went... well, it didn't. I ended up on the shuttle to ORD anyway. It could be great to fly out of LAF, but there probably needs to be more volume to make it reliable.
How are we supposed to advise undergraduates interested in applying to graduate school soon? They are scared that their options will be limited. They don't know if it is better to rush to get in or wait until things maybe get better. They don't have as many options for post-bacc programs. It's rough
This preprint was accepted @rnajournal.bsky.social! It is now online ahead of print! @cancer-inst-purdue.bsky.social @purduernaclub.bsky.social rnajournal.cshlp.org/content/earl...
ZYS-1 is not an ADAR1 inhibitor
A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
rnajournal.cshlp.org
Kyle Cottrell@kylecottrell.bsky.social · last yr.Our second preprint is out today! Post thread to come later.
Patience was rewarded. Wonderfully set and no soggy bottom.
Kyle Cottrell@kylecottrell.bsky.social · 12mo agoWhat to do while you wait for the apple pie to cool? Eat the mini pie you made with the extra pastry, of course. This hack brought to you by my grandma.
What to do while you wait for the apple pie to cool? Eat the mini pie you made with the extra pastry, of course. This hack brought to you by my grandma.
The fall bloomers are starting to make an appearance! Skip the mums, plant asters!
Welcome to the bsky account for the Purdue RNA Club! Our meeting dates for Fall 2025 are September 12, October 10, November 14, and December 5.
Anyone in the West Lafayette area have an explanation for why they closed the right lane of River Road here? It's closed for maybe 200 ft. I think that they did this either to intentionally make traffic worse or to further aggravate the businesses that didn't sell their land.
I might need to dial back the jalapeños for the next batch. 🔥🔥
Kyle Cottrell@kylecottrell.bsky.social · last yr.Our tomatillos finally started producing!
This manuscript was accepted @rnajournal.bsky.social and is online ahead of publication now! Congratulations to first author Addison Young and all the co-authors (for several this is their first publication). @cancer-inst-purdue.bsky.social 1/2 rnajournal.cshlp.org/content/earl...
PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer
A monthly journal publishing high-quality, peer-reviewed research on all topics related to RNA and its metabolism in all organisms
rnajournal.cshlp.org
Kyle Cottrell@kylecottrell.bsky.social · last yr.Just in time for #RNA25, the Cottrell Lab has posted our first independent preprint to bioRxiv. This is the first first-author publication from graduate student Addison Young and the first publication for the four undergraduate co-authors. www.biorxiv.org/content/10.1... 1/n
Here is the post thread I promised: We have been interested in ADAR1 as a therapeutic target for triple-negative breast cancer for a while. That project was supported by the NIH before Trump terminated it, but that is another story. While ADAR1 is a promising target - there aren't any inhibitors 1/n
Kyle Cottrell@kylecottrell.bsky.social · last yr.Our second preprint is out today! Post thread to come later.
So, when this gets packaged into an exosome, is it a virus? I'm only being a little sarcastic.
eLife@elife.bsky.social · last yr.A promising new approach for self-amplifying RNA that avoids triggering strong inflammatory responses in cells, paving the way for safer, longer-lasting gene therapies without immune suppression. buff.ly/xQWCPhJ
