Laboratory for Stem Cells and Cancer Research
@labriccardofodde.bsky.social
All biologists know that variation itself is nature’s only irreducible essence. Variation is the hard reality, not a set of imperfect measures for a central tendency. Means and medians are the abstractions. S.J. Gould
We are looking for an enthusiastic PhD student to join our lab (labriccardofodde.nl) to investigate how mechanical forces drive DNA damage and transcription stress in non‑dividing cells. Applications must be submitted exclusively via: www.werkenbijerasmusmc.nl/en/vacancy/1....
Riccardo Fodde's Laboratory for Stem Cell & Cancer Research
Main research goal is elucidation of molecular and cellular basis of tumor initiation and progression, translation into preventive and therapeutic intervention
labriccardofodde.nl
How I confronted my growing cynicism about academia—and rekindled my sense of purpose | Science | AAAS www.science.org/content/arti...
How I confronted my growing cynicism about academia—and rekindled my sense of purpose
“Maintaining hope doesn’t mean ignoring hardships or naïvely expecting things to work out,” this professor writes
science.org
Mathijs Verhagen, my 20th PhD student (and presumably the last one!), brilliantly defended his cum laude PhD thesis "Catching a moving target". You can download the e-version of his thesis from here: drive.google.com/file/d/1MLYa... and this is the video-link: youtube.com/live/vZZKAdR...
Choose Europe for Science: ERC welcomes new budget for 'super grants'|ERC erc.europa.eu/news-events/...
Choose Europe for Science: ERC welcomes new budget for 'super grants'
The Scientific Council of the European Research Council welcomes the offer of substantial additional budget from the European Commission for the development of a new ERC funding instrument offering la...
erc.europa.eu
just out @JNCI doi.org/10.1093/jnci...
The nucleosome remodeling and deacetylase-SWItch/sucrose non-fermentable antagonism regulates the coordinated activation of epithelial-to-mesenchymal transition and inflammation in oral cancer
AbstractBackground. Phenotypic plasticity and inflammation, 2 well-established hallmarks of cancer, play key roles in local invasion and distant metastasis
doi.org
JNCI: Journal of the National Cancer Institute has accepted Roberto Stabile's last manuscript entitled "The NuRD-SWI/SNF antagonism regulates the coordinated activation of EMT and inflammation in oral cancer" for publication. Congrats and thanks to Roberto, our lab, and all the collaborators.
At the moment, mansion-sized Asteroid 2024-YR4 has a one-in-fifty chance of hitting Earth in the next eight years. Now might be a bad time to reduce spending on Science. Just sayin’.
American chaos: standing up for health and medicine - The Lancet www.thelancet.com/journals/lan...
American chaos: standing up for health and medicine
Withdrawal from WHO and the Paris Agreements. USAID shuttered and aid halted, ceasing health programmes globally. A freeze on US$3 trillion worth of federal grants and loans, jeopardising the function...
thelancet.com
Unborn babies use genes from dad to remote control mothers for extra food #Igf2 #imprinting scitechdaily.com/unborn-babie...
Unborn Babies Use Genes From Dad to “Remote-Control” Mothers for Extra Food
Scientists at Cambridge have unveiled a fascinating mechanism where fetuses use a paternal gene to control the mother's nutrient release during pregnancy. This "remote control" system involves hormona...
scitechdaily.com
we pay, we write, we review… they profit
Happy Birthday Dr.Fauci and thank you for saving us! 💙
How to produce a first-class paper that will get published, stand out from the crowd and pull in plenty of readers www.nature.com/articles/d41...
www.nature.com/articles/s41...
Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation - Nature Genetics
Upon inflammation and targeted gene mutation, some fully differentiated secretory and postmitotic intestinal epithelial lineages dedifferentiate to acquire stem-like features and promote tumor formati...
nature.com
www.nature.com/articles/s41...
Western lifestyle, metaflammation and the cell of origin of colon cancer - Nature Reviews Gastroenterology & Hepatology
Western lifestyles cause a low-grade but chronic and metabolic inflammation (or metaflammation), which might prime committed cell lineages to initiate colon tumorigenesis. At-risk individuals might in...
nature.com
Meta loses ground to #Bluesky as users abandon Elon Musk’s X 👉 interesting update from the Financial Times 🧪 #scientificcommunity #STEM #Research #Education #Science #Academics #safeplace www.ft.com/content/e1b5...
And while we are trying to demonstrate how Western-style diet is underlying many non-communicable disease including cancer, these 5 morons eat a BigMac on their private jet doi.org/10.1038/s415...
Super cool for so many of us ➡️ The Human Tumor Atlas Network (HTAN) is constructing 3D atlases of the cellular, morphological, molecular, and spatial features of human #cancers (and their #microenvironments) over time 🧪 #mechanobiology #microscopy #physicsoflife www.cancer.gov/about-nci/or...
Human Tumor Atlas Network (HTAN)
The Human Tumor Atlas Network (HTAN) is constructing 3-dimensional atlases of the cellular, morphological, molecular, and spatial features of human cancers (and their surrounding microenvironments) ov...
cancer.gov
WTF is going on here at Blue Sky? People are civil to each other. People having intelligent discussions. People are spelling things correctly. I haven’t seen any racism or sexism. I’m confused.
a man in a lab coat is standing in front of a computer with the caption good to see you guys again
ALT: a man in a lab coat is standing in front of a computer with the caption good to see you guys again
media.tenor.com
The Baker institute in Melbourne has potentially discovered a new diabetes treatment by using cancer treatment drugs to stimulate the production of insulin in people’s existing pancreatic stem cells. Next stage is pre-clinical trials on animals
Researchers say diabetes treatment breakthrough could lead to end of insulin injections
Researchers at the Baker Heart and Diabetes Institute say they've discovered a way to make pancreatic cells produce insulin using existing cancer drugs.
abc.net.au
www.nature.com/articles/s41...
Western lifestyle, metaflammation and the cell of origin of colon cancer - Nature Reviews Gastroenterology & Hepatology
Western lifestyles cause a low-grade but chronic and metabolic inflammation (or metaflammation), which might prime committed cell lineages to initiate colon tumorigenesis. At-risk individuals might in...
nature.com
www.nature.com/articles/s41...
Non-stem cell lineages as an alternative origin of intestinal tumorigenesis in the context of inflammation - Nature Genetics
Upon inflammation and targeted gene mutation, some fully differentiated secretory and postmitotic intestinal epithelial lineages dedifferentiate to acquire stem-like features and promote tumor formati...
nature.com