🚨 New preprint! How do CA1 place cells build a brand-new spatial map when the animal enters a novel environment? We combined ensemble recordings with optogenetic silencing of direct entorhinal input to CA1, to uncover this pathway's role in remapping. Thread from Oscar below! 🐭

Oscar Chadney@oscar-chadney.bsky.social · 2mo ago

I’m excited to share our latest preprint, and the main work from my PhD, on the role of the direct entorhinal input in hippocampus CA1 spatial coding. 1/9

I’m excited to share our latest preprint, and the main work from my PhD, on the role of the direct entorhinal input in hippocampus CA1 spatial coding. 1/9

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 2mo ago

The emergence of a novel CA1 spatial map requires direct entorhinal input https://www.biorxiv.org/content/10.64898/2026.07.02.736055v1

The Moser Group is presenting our work on Wednesday afternoon at #FENS2026! •Mechanism for L-R sweeps •Attention modulation of sweeps •Grid/place remapping rules & dynamics •”Mega torus” as a hi-capacity memory space •Moving the grid bump •Development of tori & rings •RSC/HC pops. in a spatial task

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

Edvard I Moser@edvardmoser.bsky.social · 6mo ago

Is spatial navigation innate 🧠? Using #NeuroPixels we show that the #torus 🍩 underlying the #GridCell map exists already on day 10 in rats — before pups open eyes and ears and before they start upright walking. 🧵1:4 👇 www.biorxiv.org/content/10.6...

Fantastic opportunity to do pioneering single-unit recordings from the HUMAN hippocampus and other parts of the brain, with @jorgen-sugar.bsky.social at @uio.no, Norway.

Jørgen Sugar@jorgen-sugar.bsky.social · 6mo ago

We have PhD positions and Post Doc positions available! www.med.uio.no/imb/english/... Please apply if you are interested in human invasive intracranial recordings or applied machine learning in a neuroscientific context. Deadlines 1st of March (Sunday!) and 4th of March. Please RT!

Happy belated publication of some of my PhD work! Building on our findings that grid field firing rate changes can cause hippocampal remapping and memory impairment, here we show that this effect has a fixed input-output relationship, and we can even predict how place cells will remap!

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 7mo ago

Reproducible and predictable reorganization of place fields driven by grid subfield rate changes https://www.biorxiv.org/content/10.64898/2026.02.10.705142v1

My first first-author paper is on bioRxiv! Here we ask whether the same subset of neurons in ACC always display object correlates during extensive familiarisation to 2 objects. A short 🧵1/10

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 7mo ago

Heterogeneous single-cell dynamics support stable population codes for objects in the mouse anterior cingulate cortex https://www.biorxiv.org/content/10.64898/2026.02.06.704307v1