We are very excited to host an education workshop on AI for Genomic Research: From Genomic Language Models to Agentic Workflows at @mcgill.ca right after #IGES2026! Whether you are planning to attend our annual meeting or not, this is an essential workshop you won't want to miss.

My main postdoc project is now published in @AJHG! We describe a MR estimator (Quantile IV) that does not rely on parametric assumptions and allows for heterogeneous causal effects. www.cell.com/ajhg/abstrac...

A flexible machine learning Mendelian randomization estimator applied to predict the safety and efficacy of sclerostin inhibition

Mendelian randomization (MR) enables the estimation of causal effects while controlling for unmeasured confounding factors, but MR estimators often rely on strong parametric assumptions. We propose an...

cell.com

Please repost: Postdoc position in antibiotic discovery in a large multidisciplinary project combining high-throughput approaches, microscopy, AI, and hit-to-lead optimization at @umontreal.ca and @mila-quebec.bsky.social. Apply to ML.Antibiotics@gmail.com. See lnkd.in/dVVk4N3s. #microsky

Join us at UdeM and CHU Sainte-Justine! The bioinformatics community at Sainte-Justine is growing, and our clinician colleagues are really great.

Faculty position opening in bioinformatics at the University of Montreal! There is a great bioinfo and comp bio community in Montreal. www.umontreal.ca/carrieres/pr...

Out today in Nature Genetics: Using MS-based proteomics, we mapped 1,200+ plasma proteins in 2,100+ children, showing how genetics & development shape blood protein levels during childhood. nature.com/articles/s41588-025-02089-2 #PediatricProteomics #pQTL First author @liliniu.bsky.social explains ⬇️

Plasma proteome variation and its genetic determinants in children and adolescents - Nature Genetics

This mass spectrometry-based proteomic study profiles the plasma proteome in 2,147 children and adolescents and reveals its association with age, sex, puberty, body mass index and genetics.

nature.com

Excited to share a new paper from @insitro.bsky.social (first author @zmccaw.bsky.social ) in @hggadvances.bsky.social vances.bsky.social on scrutinizing the practice of using a ratio trait (numerator / denominator) for GWAS. www.cell.com/hgg-advances...

Pitfalls in performing genome-wide association studies on ratio traits

Any variant associated with either numerator or denominator will associate with the ratio in GWAS of sufficient size. Associations with ratio traits are thus not specific to the ratio. Instead, we rec...

cell.com

I used to put our open-source software on business card-sized CD ROMs & pass them out at conferences. We had code, sample data, & PDFs on the disk.

Dear early career genetic epidemiologists: The IGES Young Investigator Committee is looking for new members! It's a fun group, low time commitment, and great way to network with peers while supporting trainees around the world. Apply here by Dec 31st: www.geneticepi.org/yic_position...

🚨NEW PREPRINT! Interested in Mendelian randomization and proteomics? 🧬 We created a comprehensive multi-ancestry proteome-phenome-wide atlas of protein-disease associations in European, African, and East Asian ancestries! Preprint: www.medrxiv.org/content/10.1... Website: broad.io/protein_mr_a...