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Dave Leitch and the Leitch Lab

@leitchlab.bsky.social

Catalysis / physorg / HTE / organic synthesis research group at the University of Victoria.

201 Posts816 Follower1252 Folgt
UVic Science@uvicscience.bsky.social · 2w ago

Not all of our professors were educated at UVic, but some of them were educated by UVic alumni. And those alumni have changed the course of their lives. Read about chemistry professor David Leitch and the alumni who shaped his path. https://ow.ly/6xoA50Zs9wq

Lessons in Chemistry - Alumni - University of Victoria

UVic researcher and associate professor David Leitch is inventing new chemistry to create drugs and medicines more efficiently and with less waste.

ow.ly

Jay T. Cullen@jaytcullen.bsky.social · 3w ago

1/ 🌊 Hiring: Director of Science, @oceannetworks.ca Lead ONC's science division and help shape the future of ocean observing. A rare exec-level role for an ocean science leader 🔗 findajob.agu.org/job/8026757

Director, Science Services - Victoria, British Columbia job with Ocean Networks Canada, University of Victoria | 8026757

ONC is seeking a passionate and experienced leader and ocean science expert to drive the development and delivery of ONC’s Science division.

findajob.agu.org

Scott Bagley@bagphos.bsky.social · last mo.

Cool #ChemSky paper here from GSK in #JOCasap Neat het formations, Larock indole synthesis and a very interesting ZnCl2 accelerated SnAr on a pyrimidine tosylate Also includes my favorite amidine synthesis if you’re looking for a Pinner alternative

Zinc Binding Enhances the SNAr Route to GSK332

The route and process for the penultimate intermediate toward an mTOR inhibitor GSK332 in GSK’s respiratory portfolio is described. It relies on a heterocycle formation from a crystalline sodium ketoester enolate and an amidine derived from Pd-catalyzed cyanation of an azaindole. The final step involves an SNAr reaction through selective activation by a hindered sulfonyl chloride and Lewis acid activation to accelerate the rate.

pubs.acs.org

Jon Bois@jonbois.bsky.social · last mo.

dark helmet eating shit and then later renting a copy of the movie he's in and having to watch himself eat shit is probably the hardest i've ever laughed at a movie

screencap from spaceballs where dark helmet flies headfirst into a console
Preeti Chhibber@runwithskizzers.bsky.social · last mo.

Everyone tell me your favorite Mel Brooks bit. Could be of himself or something from one of his movies or a speech, everything funny counts Mine changes, but right now I think it may be this tiny moment in Robin Hood Men in Tights. The incredulous, “you changed it *to* latrine?” WRECKS me lmao

Andre the Chemist@andrechemist.bsky.social · last mo.

I did confirm it is not chiral! Pictured below is the same creation arranged to show it is its own mirror image. It is flipped and rotated but otherwise untouched. I'm also pretty sure it has a four-fold improper rotation axis so I'm 90% confident its point group is S4

Eight popsicle sticks interleaved with a + and an X inside a square.Eight popsicle sticks interleaved with a + and an X inside a square. The shape is the mirror image of the shape in the previous picture.
Ian Tonks@ianatonks.bsky.social · last mo.

happy to share our latest in JACS, enabling polymerization of of CO2-derived lactones through contrathermodynamic photoisomerization. Led by our amazing postdoc Arron Deacy, it's the crossover story my lab has been waiting for (Ti catalysis *and* CO2 polymers)! pubs.acs.org/doi/10.1021/...

Contra-Thermodynamic α,β- to β,γ-Photodeconjugation of an Inert CO2-Derived δ-Lactone Enables Facile Ring-Opening Polymerization

The ring-opening polymerization (ROP) of δ-lactones derived from the telomerization of CO2 and butadiene offers a platform to valorize cheap and abundant waste products into commercially competitive p...

pubs.acs.org