Proud to share our new paper in EMBO Reports! 🧬 How does a cell "decide" to become lymphatic vs blood endothelium? Turns out it's not just which genes switch on — it's how the genome folds around them. 💥 link.springer.com/content/pdf/... #Lymphatics #Zebrafish #DevBio #VascularBiology #Genomics
Laura Gutiérrez-Miranda
@lgutimiranda.bsky.social
Tiny scientist glued to a microscope 🔬. Postdoc at @lymphaticslab.bsky.social Uppsala. Former @weizmann @dkfz.bsky.social alumna #zebrafish #vascularbiology #lymphatics #marrow #microscopy 🧬✂️
Dr. Jane made an indelible mark on our understanding of chimpanzees and other species, and also of humankind and the environments we all share. She inspired curiosity, hope, and compassion in countless people, and paved the way for many others. #ThankYouJane #RememberingJane Photo: Marko Zlousic
Bassi et al. @karinayaniv.bsky.social @weizmanninstitute.bsky.social use #zebrafish to help identify new treatments for a severe lymphatic malformation. rupress.org/jem/article/... #CardiovascularBiology #HumanDiseaseGenetics
My Bioinformatics Bootcamp turned blog! Enjoy this collection of free #zebrafish resources, now posted on @the-node.bsky.social. While not comprehensive, it gives an assortment of cools tools available to researchers. Feedback would be appreciated! thenode.biologists.com/bioinformati...
Bioinformatics Bootcamp - Zebrafish Special Edition - the Node
A deep-dive into the many cool (and free) resources available to zebrafish researchers! Disclaimer: This is not a comprehensive list but a list of useful
thenode.biologists.com
Cross-posting from LinkedIn: www.linkedin.com/posts/kevin-... These are useful (and free!) websites that I found in my search for all things #zebrafish as part of my Bioinformatics Bootcamp. If there’s enough interest, I may do a blog post on the Node. Enjoy!
And just like that we get another #zebrafish surprise ! @pina85.bsky.social work introduces the Inferior Vena Cava vascular remodelling in zebrafish 🦓🐟 Congratulations to all the team for this beautiful story 👏🏻🍾
I'm thrilled to announce that my #phd work is now out in #biorxiv. Check it out here! I will be happy to have your feedback! www.biorxiv.org/content/10.1... Thank you to @karinayaniv.bsky.social, Rudra N. Das for the menthorship and all authors.
And that is a wrap! Great success of the first European #Lymphatic Symposium Next one: Budapest 2027
Axillary lymphoid organ in #zebrafish 🤩 rupress.org/jem/article/...
The axillary lymphoid organ is an external, experimentally accessible immune organ in the zebrafish
This work describes a previously uncharacterized external, experimentally accessible secondary lymphoid organ in the zebrafish located above the pectoral f
rupress.org
Do not miss it! ⬇️ @ivanbassi.bsky.social will present his latest project 🐟 #zebrafish
#EVBOSeminarSeries Moderated by Thomas Juan. Speakers: @miguel-torres-1963.bsky.social and @ivanbassi.bsky.social. ⏰When: Wednesday, 5th March 2025, EU time (2PM UK). Place: online. See you there! For registration www.evbo.org
🤩 Excited to share our protocol for computationally averaging confocal images of zebrafish lymphatic vessels to identify phenotypes! 🐟🔬 Check it out in Star Protocols 👉 star-protocols.cell.com/protocols/4030 #Zebrafish #Microscopy #StarProtocols
Not sure exactly what is going on but I have also received this message today at times where traffic should be rather low 😅 So just to be on the safe side here...Does anybody know if there is a mirror page or alternatives in case one of these days NCBI page is gone? 💨
Generation of functional oocytes from male mice🤯 www.nature.com/articles/s41...
Generation of functional oocytes from male mice in vitro - Nature
Mouse induced pluripotent stem cells derived from differentiated fibroblasts could be converted from male (XY) to female (XX), resulting in cells that could form oocytes and give rise to offspring aft...
nature.com
The first oncology clinical trial using #zebrafish avatars will start this month in Portugal. It is definitely not an easy task. But if it works, it will be a great predictive tool 💪🏻 Good luck! www.science.org/content/arti...
Fish implanted with tumor cells could help oncologists quickly personalize cancer treatments
The first clinical trial of zebrafish embryos acting as cancer “avatars” will start soon
science.org
www.nature.com/articles/s44...
Direct specification of lymphatic endothelium from mesenchymal progenitors - Nature Cardiovascular Research
Lupu, Grainger, Kirschnick et al. show that, contrary to prevailing belief, the initial specification of mammalian lymphatic endothelial cells primarily occurs from previously unidentified mesenchymal...
nature.com
The only #resolution I want for the new year 😅 www.biorxiv.org/content/10.1... #microscopy
Deep-Tissue Spatial Omics: Imaging Whole-Embryo Transcriptomics and Subcellular Structures at High Spatial Resolution
The inherent limitations of fluorescence microscopy, notably the restricted number of color channels, have long constrained comprehensive spatial analysis in biological specimens. Here, we introduce c...
biorxiv.org
I remember doing the ant maze as a lab activity few years ago...and with no communication among the members allowed...it was not so easy 😅 www.pnas.org/doi/10.1073/...
Comparing cooperative geometric puzzle solving in ants versus humans | PNAS
Biological ensembles use collective intelligence to tackle challenges together, but suboptimal coordination can undermine the effectiveness of grou...
pnas.org
Aanandita Kothurkar, @colinchulab.bsky.social, Ryan MacDonald and colleagues @ucleye.bsky.social apply IBEX to simultaneously identify all the major retinal cell types. Highlight: journals.biologists.com/jcs/article/... Article: journals.biologists.com/jcs/article/...
Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock-ins https://www.biorxiv.org/content/10.1101/2024.12.04.626907v1
Help support ZFIN and other MODs by signing this open letter 🙏 🧪
The Global Biodata Coalition has an open letter campaign to show support for sustainable funding for biodata resources. Please take a minute to read and decide if you want to sign globalbiodata.org/open-letter-... #biocuration #bioinformatics
Differential vegfc expression dictates lymphatic response during zebrafish heart development and regeneration Read this Research Article by Sierra Duca, Yu Xia, Michael R. M. Harrison, Jingli Cao and colleagues: https://buff.ly/49hhwIf
New study on clonal fate during mouse #embryogenesis using in vivo lineage tracing+ deep learning 🤯👏🏻👏🏻
(1) How can we build complex structures from a limited set of progenitors and cell types? In our new preprint, we describe patterns of cell fate decisions during early development and (in some cases) identify molecular correlates of different behaviors. www.biorxiv.org/content/10.1...
Bone remodeling is traditionally driven by osteoblasts and osteoclasts, but our study reveals a third essential player: "Type R capillaries". 🦴🔬😍 Excited to share my PhD work from Ralf H. Adams lab, now published in @natureportfolio.bsky.social Nature Cell Biology. www.nature.com/articles/s41...
Cell division is dispensable for cell differentiation during early development although it delays the differentiation rate of some cell types ⏳. www.nature.com/articles/s41...
Cell state transitions are decoupled from cell division during early embryo development - Nature Cell Biology
Kukreja et al. show that blocking cell division in zebrafish does not affect differentiation of major cell types during gastrulation and segmentation, but it does decelerate differentiation of particu...
nature.com
Vascular Thanksgiving 🙏🏻 www.nature.com/articles/s41...
An organotypic atlas of human vascular cells - Nature Medicine
A vascular cell atlas integrating single-cell data of 19 organs and tissues from 62 donors identifies angiotypic and organotypic characteristics of endothelial and mural cells.
nature.com
The fat remembers: a scientific explanation to the yo-yo effect 🪀
🧬 New in @Nature: Our team found that fat cells keep a “memory” of their previous obese state even after weight loss, helping explain why maintaining weight loss is so challenging. Excited to share this work!! www.nature.com/articles/s41...
Are you an #ECR who would like to attend a #microscopy or #bioimageanalysis training course in the next ~6 months but don't have sufficient funding, check to see if you are eligible for our JCS-FocalPlane Training Grant. Next deadline: 22 November 2024 www.biologists.com/grants/jcs-f...
#ZebrafishFunFacts: While Kimmel et al. (1995) famously standardized the embryonic development of #zebrafish, Parichy et al. (2009) takes it one step further with characterizing postembryonic zebrafish. They establish Standard Length (SL) as measure of developmental progress rather than age. 🧪
If you're just coming in from Twitter, a great way to reconnect with your community is to find the people you were following there with the Sky Follower Bridge. It works really well! www.sky-follower-bridge.dev
Sky Follower Bridge
Instantly find and follow the same users from your 𝕏 followers on Bluesky
sky-follower-bridge.dev