A paper in Nature Communications suggests that sustained visceral fat loss, rather than weight loss, is linked to better cognition and attenuation of brain atrophy years later, mainly via improved glycaemic control. go.nature.com/43nvaY6 🧪
Rajat Singh Lab
@lipophagy.bsky.social
Professor of Medicine @UCLA Director @UCLA Liver Research Center Quit clinics for research 🔬 **My Views!** 👉🏼 Autophagy and acidic organelles 👉🏼 MASLD spectrum - HCC newbie 👉🏼 Biology of aging 👉🏼 Guitar
Akayama, Shima, Nakamura et al. show that TFEB is regulated by at least two different regulatory mechanisms during lysosomal damage: ATG conjugation system–dependent/independent regulation. rupress.org/jcb/article/... 📕 Part of #Lysosomes 2026: rupress.org/jcb/collecti...
Intestinal macrophages modulate synucleinopathy along the gut–brain axis www.nature.com/articles/s41...
Intestinal macrophages modulate synucleinopathy along the gut–brain axis - Nature
Muscularis macrophages, housekeepers of enteric nervous system integrity and intestinal homeostasis, modulate α-synuclein pathology and neurodegeneration in models of Parkinson’s disease, and understa...
nature.com
A paper in Nature Metabolism describes a sensory circuit involving the medial septum (MS), where MS glutamatergic neurons integrate food odours to prime satiety and regulate nutrient intake. go.nature.com/404U917 🧪
www.nature.com/articles/s41... Stellate cells shape the zonal liver architecture and function.
Hepatic stellate cells control liver zonation, size and functions via R-spondin 3 - Nature
Hepatic stellate cells regulate hepatocyte functions via R-spondin 3.
nature.com
To my mentors, colleagues, fellows and students, who taught me how to think, taught me science, patience and empathy, who now inspire me to fight! Here’s to you ✊🏼✊🏼✊🏼✊🏼✊🏼
Thank you Drs. Dan Klionsky and Dimitra Dialynaki for your commentary on our work: www.tandfonline.com/doi/epdf/10....
Identification of the mammalian VPS4A as a selective lipophagy receptor
tandfonline.com
Getting ready to say goodbye to 2024! Gratitude for the best team ever 🙏🙌💪
go.bsky.app/2zGz8ot Autophagy Starter Pack - for those interested in autophagy (macro, micro and CMA), lysosomes and late endosomes! Let’s join hands to degrade the trash 😃
Types of aging paper
Simon Fisher@profsimonfisher.bsky.social · 2y agoTo accompany all those Bluesky science/academia #starterpacks, how about we also share introductions to the literature of our different fields. I present here a handy guide to main types of papers in the language sciences (inspired by the amazing @xkcd.com). #language #linguistics #science #academia
Started an Autophagy Starter Pack: please let me know if you’d like to be added. Thanks.
Rajat Singh Lab@lipophagy.bsky.social · 2y agogo.bsky.app/2zGz8ot Autophagy Starter Pack - for those interested in autophagy (macro, micro and CMA), lysosomes and late endosomes! Let’s join hands to degrade the trash 😃
Autophagy... the must-have starter pack to elongate the autophagists community 😍😍😍
Rajat Singh Lab@lipophagy.bsky.social · 2y agogo.bsky.app/2zGz8ot Autophagy Starter Pack - for those interested in autophagy (macro, micro and CMA), lysosomes and late endosomes! Let’s join hands to degrade the trash 😃
go.bsky.app/2zGz8ot Autophagy Starter Pack - for those interested in autophagy (macro, micro and CMA), lysosomes and late endosomes! Let’s join hands to degrade the trash 😃
go.bsky.app/2zGz8ot #Autophagy and #Lysosomes starter pack. Let’s get united! 🦋
🦋 #bluesky is finally taking off! Mastodon didn’t have the momentum but here we go 🤩 spread the word 🚨 don’t delete X straight away. There are several ways to find contacts here. Not just #starterpacks I think I used the browser extension Sky Follower Bridge . Quicker than you think! 🧪
Kai Kupferschmidt@kakape.bsky.social · 2y agoLooks like Bluesky will cross 20 million users some time before I wake up tomorrow morning ET. The platform had 10 million users 2 months ago. It had about 15 million users a week ago. bsky-users.theo.io
Folks in science who do music - anyone around the LA area looking to jam? 🙏
Interesting but not a surprising observation in the grand scheme of events. Also, the contribution of this mechanism to rebound weight gain is likely to be limited unless it affects food intake per se. www.nature.com/articles/s41...
Adipose tissue retains an epigenetic memory of obesity after weight loss - Nature
Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to th...
nature.com
Well, hello everyone! It’s so refreshing to be on this amazing platform! Breathing again!
Lab lunch to celebrate new publication! 🙏🎉🎊🍾 👉🏼 Congratulations Debajyoti Das and Mridul Sharma 👍
