Thrilled to be back in my home state preaching the gospel of Actin. Big thanks to Rice Bioengineering for the invitation to present my work!
Blake Hernandez
@loxstoplox.bsky.social
PhD student @ UPenn | Early mammalian development, mitosis, & microscopy
Another aspect to consider is how much colors are saturated, depending on the LUT, the screen type and settings it can make a huge difference on data readability. Green Fire Blue is popular but really saturated
Not all colormaps are created equal. Notice the nonlinear brightness scaling in two very popular ImageJ LUTs! (Glow & GFB)
Let's start the week with this movie kindly shared by @loxstoplox.bsky.social The movie shows a mouse embryo labeled with Formin-2-GFP and SPY650-DNA during nuclear envelope breakdown. Note the nuclear dilution of Formin-2-GFP immediately before the SPY650-DNA labeled chromosomes start compaction.
New findings in Science demonstrate that successful mitosis may draw on more mechanisms than commonly assumed. Learn more in this #SciencePerspective: scim.ag/4dFbqnp
Rewriting the rules of cell division
Microtubules get help from actin filaments during mitosis
scim.ag
I’m excited to announce that my paper describing non-canonical mitotic mechanisms in the early mouse embryo is out in @science.org ! (link at end of 🧵)
Actin does it again #cytoskeletonwar
Actin organizes chromosomes and microtubules to ensure mitotic fidelity in the preimplantation embryo
Following fertilization, the preimplantation embryo undergoes successive rounds of cell division and must accurately propagate the genetic material to ensure successful development. However, early mam...
science.org
Christophe 🔬 Leterrier@christlet.bsky.social · last yr.Yet another microtubule-based structure that needs actin #cytoskeletonwar @manuelthery.bsky.social
Dynamic mitochondria labeled with PKmito #FluorescenceFriday
What started as a brief chat with @buvansr.bsky.social and @vgelfand.bsky.social at the 2023 CellBio meeting @ascbiology.bsky.social has grown into our published collaborative work on single vimentin IF dynamics and organization in cells. Love when stuff like that happens.
Journal of Cell Biology@jcb.org · last yr.Renganathan, Moor, @vgelfand.bsky.social et al. use single-particle tracking to show that #vimentin intermediate filaments display active movement throughout the cell, with individual filaments within a bundle moving independently rupress.org/jcb/article/... #Cytoskeleton #Microscopy
