Melanin synthesis begins with the shuttling of tyrosine into the lumen of organelles called melanosomes, but the transporter performing this function has remained elusive for over 30 years. Our new preprint identifies SLC16A6 as a melanosomal tyrosine transporter! www.biorxiv.org/content/10.6...
SLC16A6 is a tyrosine transporter for the melanosome
Cells enable specialized metabolism by compartmentalizing metabolic pathways into distinct organelles, which requires the membrane transport of metabolites. In melanocytes, the amino acid tyrosine is ...
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