New in JLR press| The monoacylglycerol acyltransferase 2 inhibitor VB-85387 reduces MASLD. Learn more: www.jlr.org/article/... #JLipidRes

#WorldAlzheimersDay | In MCP, researchers used ultrasensitive proteomics to find that aging amplifies neuroinflammation, cytoskeleton remodeling and phosphorylation in Alzheimer's disease models: www.asbmb.org/asbmb-today/.... #MolCellProt | @asbmbjournals.bsky.social

Peer reviewers play a vital role in advancing scientific discovery. Their evaluations help ensure that published research meets the highest standards of quality and integrity. As #PeerReviewWeek comes to a close, we thank all reviewers who support ASBMB journals. www.asbmb.org/asbmb-today/...

During #PeerReviewWeek, ASBMB is proud to recognize & thank all outstanding reviewers who support ASBMB journals! Learn about JBC, MCP & JLR reviewers whose exceptional dedication is reflected in the quality, timeliness and consistency of their reviews: www.asbmb.org/asbmb-today/....

Celebrating outstanding reviewers across ASBMB journals

Editors recognize the heavy-lifters and rising stars during Peer Review Week.

asbmb.org

Lysine Butyrylation Modulates Central Carbon Metabolism and Photosynthesis in Cyanobacteria - Journal of Biological Chemistry www.jbc.org/article/S002... @asbmbjournals.bsky.social

Lysine Butyrylation Modulates Central Carbon Metabolism and Photosynthesis in Cyanobacteria

Cyanobacteria, evolutionarily ancient photoautotrophs, serve as key model organisms for studying diverse biological processes. Lysine butyrylation (Kbu) is an emerging post-translational modification ...

jbc.org

Epigenetics and chromatin biology are at the heart of genome regulation. Explore #JBiolChem's latest virtual issue featuring studies on DNA methylation, histone modifications, chromatin remodeling, noncoding RNAs and transcriptional control: www.jbc.org/epigenet.... #ASBMBJournals

New in JLR| FBiosynthesis and analytics of specialized pro-resolving mediators: facts and faults. Learn more: www.jlr.org/article/... #JLipidRes

🧠 New research in JLR links early cognitive decline to reduced levels of protective omega-3-derived oxylipins in HDL, the so-called "good cholesterol." Learn more: www.asbmb.org/asbmb-today/... #Cholesterol #LipidResearch #JLipidRes #ASBMBJournals | @asbmb.bsky.social

Changes in HDL lipids linked to early cognitive decline

A targeted lipidomics study finds that the anti-inflammatory oxylipin cargo of HDL is depleted in men and Hispanic adults with mild cognitive impairment, independent of cholesterol levels.

asbmb.org

New in JBC press| Denuded peptidoglycan oligosaccharides enable the biochemical investigation of bacterial cell wall recognition, modification, and degradation. Learn more: www.jbc.org/article/... #JBiolChem

JLR Editorial Board member Paul Huang of Fudan University will present a UPMC (@news.upmc.com) seminar on Aug. 27 at 12 p.m. EDT: "When Immunity Redirects Lipids: Lipoprotein Transit Determines Psoriasis Comorbidities" ➡️Join virtually or in-person cim.pitt.edu/seminar-seri... #JLipidRes

New in JBC press| Active site motifs of the Nem1 protein phosphatase confer its function in yeast lipid synthesis. Learn more: www.jbc.org/article/... #JBiolChem

The artwork on the cover of the June 2026 issue of JBC depicts PI5P4Kγ as a central organizing hub within a dynamic intracellular interaction network identified by proximity labeling. Inspired by Llorente et al.: www.jbc.org/article/... #ASBMBJournals #JBiolChem

New in JBC press| A covalent inhibitor targeting Cys-349 of LIMK1 confers selectivity over LIMK2. Learn more: www.jbc.org/article/... #JBiolChem

This is my most comprehensive guide to Databases & tools for Biochemistry, Molecular Biology, etc. (a non-exhaustive list of some of the main sources of data, analysis tools, and other tools I’ve found useful). As always, I hope you and/or your trainees can find it useful too! youtu.be/rdEP6qe2jok

Databases & tools for Biochemistry, Molecular Biology, Biology, etc.(my most comprehensive guide)

YouTube video by the bumbling biochemist

youtu.be

⏯️Webinar replay: Everything you wanted to know about pre-mRNA splicing but were afraid to ask 🎤 Speaker: Aaron Hoskins, @uwmadisonrna.bsky.social Watch for an overview of pre-mRNA splicing and the cellular machine responsible — the spliceosome: www.youtube.com/watch?v=Hf2w.... #RNAResearch

Everything you wanted to know about pre-mRNA splicing but were afraid to ask

YouTube video by American Society for Biochemistry and Molecular Biology (ASBMB)

youtube.com

The Journal of Lipid Research (JLR) is a leading open access journal dedicated to publishing high-quality research on lipid biology, metabolism, and function. Discover more about the journal, its scope, and how to submit your research. spkl.io/633247JAfj

Molecular & Cellular Proteomics (MCP) is a leading open access journal dedicated to advancing proteomics across both basic and translational research. Discover more about the journal, explore the latest research, or submit your work. spkl.io/633227JA70

🎉 Congratulations to Leonard Rorrer, our July MOBILion Champion! A trusted technical leader, Leonard has helped advance our proteomics efforts, co-led a paper accepted in Molecular & Cellular Proteomics, and played a key role in validating our prototype system. Well deserved! 👏

A Platform for High-throughput and Ultrasensitive Immunopeptidomics - Molecular & Cellular Proteomics www.mcponline.org/article/S153...

A Platform for High-throughput and Ultrasensitive Immunopeptidomics

In BriefImmunopeptidomics enables untargeted discovery of peptides presented by MHC molecules, informing vaccine and immunotherapy development. Existing workflows focus either on throughput or sensiti...

mcponline.org

Access the paper here: www.mcponline.org/article/S153... #MolCellProt #ASBMBJournals

Region-Resolved Integrative Multi-Omic Characterization Reveals Diverse Tumor and Microenvironment Features of Pituitary Neuroendocrine Tumors

In BriefThis study presents the first region-resolved, multi-omic characterization of pituitary neuroendocrine tumors (PitNETs), revealing distinct molecular and microenvironmental features between ca...

mcponline.org

ENEA Young Researchers Committee (EYRC)@eyrc.bsky.social · 4mo ago

Neuroendocrinology Watch by EYRC! This week, we highlight a study by Xie et al., published in Molecular & Cellular Proteomics, which characterized diverse tumor and microenvironment features of pituitary neuroendocrine tumors (PitNETs). => More on LinkedIn

Phosphate release from myosin Va occurs after the initial powerstroke but before the secondary powerstroke associated with ADP-release - Journal of Biological Chemistry www.jbc.org/article/S002...

Phosphate release from myosin Va occurs after the initial powerstroke but before the secondary powerstroke associated with ADP-release

Myosins transduce chemical energy into mechanical work, with key steps being the powerstroke and the release of phosphate (Pi) from the active site. This process is still poorly understood, in part, b...

jbc.org

Proton pump rhodopsins for optogenetic manipulation of biological activities and beyond - Journal of Biological Chemistry

Proton pump rhodopsins for optogenetic manipulation of biological activities and beyond

Water (H2O), the principal component of living organisms including humans, dissociates into H+ and OH- in aqueous environments, and the resulting H+ concentration determines both cellular pH and the proton motive force (PMF) across cellular membranes. These physicochemical parameters are fundamental regulators of a wide range of biological processes. Optogenetics enables the manipulation of biological and cellular functions using light, typically through the ectopic expression of microbial rhodopsins as photoreceptive proteins in target cells or organs.

jbc.org

Celebrating the impact of Journal of Biological Chemistry. For more than a century, the Journal of Biological Chemistry has been the forefront of publishing rigorous, high-quality research that advances our understanding of the molecular and cellular basis of biological processes. spkl.io/633287JAAK

New in JBC press| Scientists' results support a model in which conformational gating regulates persulfide transfer. Learn more: www.jbc.org/article/... #JBiolChem

New in MCP press| A temporal phospho-acetylome atlas of human myogenesis identifies coordinated post-translational regulation. Learn more: www.mcponline.org/ar... #MolCellProt

Nominations are now open for the Journal of Lipid Research Jr. Associate Editor Program — a 3-year mentored editorial opportunity for early-career faculty (≤10 years post-terminal degree). Send nominations (CV included) to JLR@asbmb.org & learn more about the program: www.jlr.org/junior-assoc....

New in JLR press| The p53 – CerS6 interaction on the ER integrates p53 and sphingolipid signaling pathways in metabolic stress response. Learn more: www.jlr.org/article/... #JLipidRes

New in JBC press| Rational engineering of the Arabidopsis thaliana plant cysteine oxidase 4 active site can reduce biochemical activity and improve submergence tolerance. Learn more: www.jbc.org/article/... #JBiolChem

OK, not a "tremendous breakthrough", but it is nice to have it completed - the first project in the group, started after moving to @hhu.de years ago, as a part of CRC 1208 (1st C is for "collaborative"). Thanks to all the co-authors for the joint effort and resilence ✊🤓 www.jbc.org/article/S002...

Conformational dynamics of the membrane-anchored foldase LipH from Pseudomonas aeruginosa governs recognition and release of its client lipase

The lipase LipA from Pseudomonas aeruginosa is an extracellular enzyme that plays an important role in bacterial infections. Prior to its export via the type II secretion system, LipA requires the cog...

jbc.org

And it was a great experience to publish in J Biol Chem @asbmb.bsky.social: from rapid processing by the Editorial office (out for reviewing in 48 hours!) to quick and constructive peer-review. 🌟