Thrilled to see nano-CUT&Tag applied in Drosophila for the first time in an exciting collaboration with the lab of Mattias Mannervik! Long story short: It works beautifully Huge kudos to the computational team for turning complex single-cell chromatin data into exciting developmental landscapes.
Have you ever wondered how chromatin states shape developmental trajectories? In our preprint, we address this question using single-cell nanoCUT&Tag, a method developed by Marek Bartosovic @mardzix.bsky.social, which simultaneously profiles active H3K27ac and repressive H3K27me3 in the same nucleus