@sonideshwal.bsky.social et al (rupress.org/jcb/article/...) reveal a system by which mitochondria prioritize CoQ retention when the mevalonate pathway is impaired, preserving respiration at the expense of antioxidant defenses, highlight @angelifriedmann.bsky.social et al rupress.org/jcb/article/...

@brasil.dw.com @g1portal.bsky.social g1.globo.com/google/amp/s...

Pesquisador brasileiro ganha prêmio na Alemanha por estudo sobre câncer | G1

O pesquisador brasileiro José Pedro Friedmann Angeli foi premiado por avanços na ferroptose, mecanismo que pode combater tumores agressivos e resistentes.

g1.globo.com

I have two post doctoral positions available in my lab funded by the Wellcome Trust to develop new chemical biology approaches to studying mitochondria. Would suit those with interest in both mitochondria and chemical biology. Advert below-please forward and repost! www.cam.ac.uk/jobs/researc...

There’s a special place in hell for reviewers who simply toss the document they’re supposed to review into an LLM model.

EXO Chat w/ Prof. Norbert Perrimon (Harvard/HHMI) and 1st author Dr. Myeonghoon Han, from his lab, about their EXO review on deorphanizing the secretome: where biochemistry, genetics, and AI meet. www.sciexplor.com/exo/podcast/3

EXO - Beyond the Cell | Science Exploration Press

sciexplor.com

One of the best parts of leading a department is the opportunity to recruit exceptional people who will shape its future. Today, I'm thrilled to share that we are recruiting a W3 Professor of Translational Hepatitis Virus Research at Heidelberg University. www.nature.com/naturecareer...

W3 Professorship in Translational Hepatitis Virus Research (m/f/d) - Heidelberg, Baden-Württemberg (DE) job with WESTPRESS GmbH & Co. KG | 12861212

The Heidelberg Medical Faculty of the University of Excellence Heidelberg is an outstanding location for innovative research, both nationally and i...

nature.com

Explore #mitocancer insights from @angelifriedmann.bsky.social & @veraskafar.bsky.social on how #riboflavin influences #mitochondrialfunction #ferroptosis & strategies to block #mitochondria driven resistance mechanisms in cancer! @nature.com mitoworld.org/riboflavin-m... #UMDF #mitoscientists

Riboflavin Modulates Lipid Peroxidation and Ferroptosis - MitoWorld

A multi-institute research team, led by Prof. José Pedro Friedmann Angeli, examined the activity of ferroptosis suppressor protein 1 (FSP1) in protecting against phospholipid peroxidation and ferropto...

mitoworld.org

happy to share our review collection “Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Opportunities” @oncogenesisnature.bsky.social . A big thank you to all contributing authors. If you are interested in cancer metabolism, I encourage you to read these expert reviews. enjoy!!

Oncogenesis@oncogenesisnature.bsky.social · 2mo ago

🚀📚 Excited to share the launch of the review collection "Metabolic Reprogramming in Cancer: Mechanisms and Therapeutic Opportunities", edited by Shensi Shen (@seansi.bsky.social) and Jean-Ehrland Ricci (@jer-06.bsky.social). 📖 Discover the Review Collection: www.nature.com/collections/...

New Paper in Science Advances: Researchers at JMU discovered that a molecule can act as a biological “double agent”: while blocking one important #cell process, it also disables a key protective mechanism. #CellBiology #Pharmakology 📸 generated with AI ➡️ go.uniwue.de/gohla-cp1

Online now! Online now! The molecular basis for nuclear pore destruction by a proximity-inducing molecular glue #chembiol

The molecular basis for nuclear pore destruction by a proximity-inducing molecular glue

Hinshaw et al. determine the molecular basis for TRIM21 recruitment to the nuclear pore protein NUP98, showing that an induced protein-protein interface drives the potency and selectivity of the molecular glue mechanism.

dlvr.it

“Fatty acid channelling into triglycerides and oxylipins drives ferroptosis resistance during oncogenic BRAF-induced senescence” An interesting link between lipid metabolism in OIS cells and their resistance to ferroptosis and oxidative stress ⤵️ www.nature.com/articles/s41...

Excellent and highly insightful review - A must-read for researchers interested in lymphoma and cancer metabolism. Thank you Chris for contributing to our special issue in @oncogenesisnature.bsky.social on « metabolism and cancer » www.nature.com/articles/s41...

Metabolic vulnerabilities and therapeutic opportunities in diffuse large B-cell lymphoma - Oncogenesis

Oncogenesis - Metabolic vulnerabilities and therapeutic opportunities in diffuse large B-cell lymphoma

nature.com

📍 Registration is now open for this #Redox #BiochemicalSociety Meeting! Excellent invited speakers, plus many slots for elevated talks from abstracts, including #ECRs 🫵 🌍 Cambridge, UK 🗓️ 16-18 Nov 2026 ⏳ Super early bird deadline: 16 Aug 2026 🌐 bit.ly/Redox-26 #BiochemEvent @biochemsoc.bsky.social

Biochemical Society@biochemsoc.bsky.social · 3mo ago

Join us in Cambridge from 16-18 November 2026 to celebrate the latest research in redox biology! Featuring insights into redox regulation, metabolism, cell death, hypoxia and more. Organised by @cochemelab.bsky.social, @jamesnathanlab.bsky.social, Phil Eaton and Andy Finch: https://ow.ly/UbTJ50YZxFg

Pleased to share our recent work out today in @natmetabolism.nature.com. This study addresses a longstanding mystery - NRF2-driven cancers increase cysteine acquisition (via xCT) by ~5x - so where does all that cysteine go?

Nature Metabolism@natmetabolism.nature.com · 4mo ago

Uproar in Germany over law requiring men get military approval for long stays abroad www.theguardian.com/world/2026/a...

Uproar in Germany over law requiring men get military approval for long stays abroad

Clause says those aged up to 45 may need permission from armed forces to leave country for more than three months

theguardian.com

If you are a postdoc or grad students that wants to be considered for a talk at the GRS then get your abstract in! (Deadline 5th April).

Claudia Lennicke@claudialennicke.bsky.social · 5mo ago

The GRS is immediately followed by the Gordon Research Conference (GRC), chaired by @elizabethveal.bsky.social and @giedroclab.bsky.social. Attending both allows you to present your work, build connections with fellow ECRs, and then engage with leading investigators in the field

If a week by the Mediterranean discussing the latest research Bridging Redox Chemistry to Biology, Aging and Disease sounds like a welcome escape, then this Gordon Research Conference could be for you! www.grc.org/thiol-based-...

Excited to co-chair the 2026 Gordon Research Seminar (GRS) on Thiol-Based Redox Regulation & Signaling with Taylor Covington, a meeting for early career researchers in redox research 📍 Castelldefels (Barcelona), Spain ☀️ 📅 July 11–12, 2026 #Redox #Thiols #EarlyCareerResearchers More details ↓

Very grateful to receive the Deutscher Krebspreis 2026 (Experimental Cancer Research) together with Marcus Conrad. This recognition reflects the incredible efforts of our teams and collaborators over the years @uni-wuerzburg.de

Isn't this like normal?

Happy to share the final version of the study where we describe a central role for vitaminB2 in regulating membrane redox state - some new cool experiments were added since the preprint was posted - pls check this out thttps://www.nature.com/articles/s41556-025-01856-x

Riboflavin metabolism shapes FSP1-driven ferroptosis resistance - Nature Cell Biology

After performing a focused CRISPR–Cas9 screen, Skafar et al. identify riboflavin (vitamin B2) as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in c...

nature.com

Interested in investigating dietary and metabolic regulation of immune responses? We have a PostDoc and a PhD position available in the lab. karriereamukb.de/jobs/postdoc...

A study in Nature Cell Biology identifies riboflavin, vitamin B2, as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in cancer cells. underscoring the therapeutic potential of targeting riboflavin metabolism. go.nature.com/4blD8Gi #medsky 🧪

Interesting and systematic evaluation that consolidates many observations the field has already been converging on: GPX4 dependency appears to be overestimated in vivo. Suggesting that exploiting high-PUFA states in specific cancer entities is unlikely to benefit from single-target GPX4 inhibition.

bioRxivpreprint@biorxivpreprint.bsky.social · 5mo ago

Systematic Evaluation Defines the Limits of Ferroptosis in Cancer Therapy https://www.biorxiv.org/content/10.64898/2026.03.11.711115v1

Interesting and systematic evaluation that consolidates many observations the field has already been converging on: GPX4 dependency appears to be overestimated in vivo. Suggesting that exploiting high-PUFA states in specific cancer entities is unlikely to benefit from single-target GPX4 inhibition.

bioRxivpreprint@biorxivpreprint.bsky.social · 5mo ago

Systematic Evaluation Defines the Limits of Ferroptosis in Cancer Therapy https://www.biorxiv.org/content/10.64898/2026.03.11.711115v1

#Vitamin B2 is converted into molecules which protect cells from oxidative damage. The downside: It also protects #cancer cells. Scientists at the Rudolf Virchow Centre at #JMU discovered that. 📸 Natalie Fahmer ➡️ www.uni-wuerzburg.de/en/news-and-...

Happy to share the final version of the study where we describe a central role for vitaminB2 in regulating membrane redox state - some new cool experiments were added since the preprint was posted - pls check this out thttps://www.nature.com/articles/s41556-025-01856-x

Riboflavin metabolism shapes FSP1-driven ferroptosis resistance - Nature Cell Biology

After performing a focused CRISPR–Cas9 screen, Skafar et al. identify riboflavin (vitamin B2) as a regulator of FSP1 stability that modulates phospholipid peroxidation and ferroptosis sensitivity in c...

nature.com

New online: FAD-dependent stabilization of FSP1 promotes ferroptosis resistance

FAD-dependent stabilization of FSP1 promotes ferroptosis resistance

Nature Structural & Molecular Biology, Published online: 13 March 2026; doi:10.1038/s41594-026-01760-4The oxidoreductase FSP1 recycles radical-trapping antioxidants that suppress oxidative lipid damage and ferroptosis. A series of genetic screens reveal a key role for the vitamin B2 metabolite flavin adenine dinucleotide in stabilizing FSP1, preventing its proteasomal degradation and promoting ferroptosis suppression.

dlvr.it

🧐 What if metabolic defects are not just a consequence of inflammatory disease - but actively contribute to it? Inflammation and metabolism are deeply intertwined, but the molecular links remain unclear. Our new paper in Cell Death & Differentiation uncovers one. 🧵👇 nature.com/articles/s41...