Mark van Raaij
@markvanraaij.eurosky.social
Structural biologist, virus proteins, bacteriophages, expresser and purifier, crystallisation, macromolecular crystallography, commissioning editor for Acta Cryst F.
WebCalEM is a browser-based tool that makes lattice-based pixel-size calibration a routine step in the cryo-EM workflow #CryoElectronMicroscopy #MagnificationCalibration #PixelSize doi.org/10.1107/S205...
Please look at our structure of the Salmonella bacteriophage epsilon15 tailspike. We show activity for the “usual” LPS hydrolysis site and an esterase site by NMR and structures with LPS. It reveals multiple O-antigen binding sites and a protruding esterase domain www.biorxiv.org/content/10.6...
The structure of the Salmonella phage epsilon15 tailspike reveals multiple O-antigen binding sites and a protruding esterase domain
Many bacteriophages use tailspikes to degrade host bacterial polysaccharides, facilitating access to the outer membrane. The homotrimeric tailspikes of the Salmonella phage epsilon15 feature a slender...
biorxiv.org
🚨BREAKING: Our union of over 12,000 baristas are officially calling for a Starbucks boycott. Read this statement penned by Starbucks workers on why a boycott from ALL customers, allies, and organizations is necessary to fight back against corporate greed:
The crystal structure of LegY, a putative glycosidase effector from L. pneumophila, was determined to 1.46 Å resolution and is structurally assigned as a member of glycoside hydrolase family 15 #LegionellaPneumophila #BacterialToxin #Glycosidase doi.org/10.1107/S205...
We would like to invite you to share protocols that will be useful to the community, and help maintain Acta Crystallographica Section F and and the other IUCr Journals as important references for how structural biology research is performed doi.org/10.1107/S205...
I am telling you, academics: just reclaim your journals, don't wait commercial publishers to kick you out, they are just here for 30%+ profit, feeding on public money. (Re-)start your own Diamond Open Access journal.
🚨Elsevier forces out Games and Economic Behavior (GEB) Editor, entire editorial board has resigned, current board only handling new submissions until Nov. 14 #econsky
Presenting the first article in our new 'Protocols' category: Helical reconstruction of amyloids in cryoSPARC #Amyloids #CryoEM #HelicalReconstruction doi.org/10.1107/S205...
The Trump Admin’s attack on science hurts American lives directly with public health pseudoscience & climate change denialism. Fighting back against the Trump Admin isn’t just a fight for science - it’s also a fight for every American. Article: zurl.co/VX3UD
With their assault on science, Trumpists aren’t just harming America – they’re harming themselves | Jan-Werner Müller
The administration is subjugating science to political imperatives, a major blow to US soft power and technological progress
zurl.co
The crystal structure of human DKK4-CRD1 determined at 1.83 Å resolution reveals a compact fold comprising N- and C-subdomains connected by a linker region and stabilized by five conserved disulfide bonds #WntSignaling #Dickkopf4 #CysteineRichDomain1 doi.org/10.1107/S205...
August issue is out! journals.iucr.org/f/issues/202... On the cover: the crystal structure of LegY, a putative glycosidase effector from Legionella pneumophila, shows high similarity to fungal glucoamylases but shares lower homology with known prokaryotic counterparts doi.org/10.1107/S205...
open.spotify.com/track/2aZsp1... This came up on my running playlist, forgot I put it there but does seem appropriate for the times
Kristallnaach
BAP · Vun Drinne Noh Drusse · Song · 1982
open.spotify.com
Dr. Anthony Fauci urges Americans not to accept "Normalization of Untruths".
Yeppers. I am no longer going to conferences in the U.S. And I am not alone.
Detentions of International Scholars at Airports Raise Alarm
A Johns Hopkins University researcher was detained at an airport by immigration officials and later released. Cases like hers make travel fraught for foreign scholars.
insidehighered.com
Ok, time to feel old – for a good cause 😃 I was in the middle of my PhD when our journal was launched. An online-only journal at a time when most others were not. This is by definition a VERY special issue. Have a look at what papers we're looking for and be a part of the future of the journal!
(IUCr) Submit an article to a special issue
Submit an article to a special issue
journals.iucr.org
We're celebrating 20 years of Acta Crystallographica Section F!🎉🥳 Join us by contributing to our celebratory collection of articles, which is now open for submissions! Find out more at journals.iucr.org/special_issu...
www.theguardian.com/commentisfre...
The Democrats have one last chance to halt the erosion of US democracy – and it’s less than 100 days away | Timothy Garton Ash
American democrats need a Hungarian-style landslide to overwhelm Trump’s attempts to rig November’s midterm elections, says Guardian columnist Timothy Garton Ash
theguardian.com
The structure of the Salmonella phage epsilon15 tailspike reveals multiple O-antigen binding sites and a protruding esterase domain https://www.biorxiv.org/content/10.64898/2026.07.31.742079v1
Preprint alert‼️ My long-awaited epsilon15 tailspike article is available in bioRxiv
The structure of the Salmonella phage epsilon15 tailspike reveals multiple O-antigen binding sites and a protruding esterase domain https://www.biorxiv.org/content/10.64898/2026.07.31.742079v1
Some questions for our structural biology community: What protocols do you think would be useful to have? Do you prefer to watch step-by-step videos, or follow written instructions? Of course, not everything has to be a video, but certain workflows are simply best documented on video #protocols
A new type of article for Acta F: Protocols The purpose of this new category is to provide to the reader procedures that are sufficiently detailed so other researchers can reproduce the described workflow. Find out more in 'Show me how it's done: introducing Protocols': doi.org/10.1107/S205...
"f you are hunting for a COVID villain[,] investigate crooks who promoted quack remedies...sources of anti-vaccine disinformation...No mistakes by the scientific community begin to compare with the [right's] brutal indifference to the well-being of Americans" www.theatlantic.com/ideas/2026/0...?
Anthony Fauci Is Not the Villain in This Story
The doctor was thrust into his pandemic-leadership role because of Trump’s deadly dereliction of duty.
theatlantic.com