🚨 New paper in @nature.com We asked why two hippocampal areas with very different anatomy, CA3 and CA1, often seem to code space so similarly? By recording bats flying up to 200m, we found that the difference was hidden by scale! www.nature.com/articles/s41... 🧵 1/11

Sparse-to-dense coding transformation between hippocampal areas CA3 and CA1 - Nature

The hippocampus exhibits a CA3-to-CA1 coding transformation that combines fast learning with an efficient, compressed neural code.

nature.com

It's a wrap! Grateful for this incredible #BonnBrain26 team. Many thanks to our fantastic support crew of the @dzne.science, @mpinb.mpg.de and @unibonn.bsky.social - we could not have done this without you! See you in 2028 for the next edition!

“The interesting part is what exactly seems to be stable and what exactly seems to be drifting,” says @trose-neuro.bsky.social. #neuroskyence By @avaskham.bsky.social www.thetransmitter.org/spatial-cogn...

I’m incredibly honored and grateful to have received the Best Young Investigator Talk Award at the BonnBrain Conference 2026! 🧠🦎 I truly enjoyed the inspiring discussions and new connections throughout the event—thanks to the organizers and everyone who made it such a great experience! #BonnBrain26

Thank you #BonnBrain26 for selecting me to present my work. I had a blast and it is so much fun being back home! And thank you to all the people who voted my talk (second) best! I will dedicate todays speaker dinner to you. Today, come around for a chat at my poster A13. #BonnBrain

This is big!

Matteo Guardamagna@matteoguardamagna.bsky.social · 5mo ago

1/7 🧠 My journey into development begins with this work and question: how does the brain's spatial navigation system develop? We found that the neural networks for spatial navigation (tori and rings) are preconfigured and only later anchor gradually to the world with experience! 🧵

A half-century old question may have its final answer. Using high-resolution #Mini2P microscopes, we find no evidence of local topography in #PlaceCells. Place fields of neighbouring cells are no more similar than those of randomly selected cells. 🧠🗺️ Out now in @pnas.org www.pnas.org/doi/10.1073/...

Place cells in CA1 lack topographical organization of firing locations | PNAS

Topography is a well-described and well-known concept for cortical organization in primary sensory and motor cortices of mammalian brains. Similar ...

pnas.org

My first first-author paper is on bioRxiv! Here we ask whether the same subset of neurons in ACC always display object correlates during extensive familiarisation to 2 objects. A short 🧵1/10

bioRxiv Neuroscience@biorxiv-neursci.bsky.social · 6mo ago

Heterogeneous single-cell dynamics support stable population codes for objects in the mouse anterior cingulate cortex https://www.biorxiv.org/content/10.64898/2026.02.06.704307v1

Do you love quantifying animal behavior as much as we do? We have just the tool for you! Presenting #OCTRON - a pipeline that helps you create rich annotation data and enables training of custom segmentation models. Have a look, particularly if you work with non-model / invertebrate organisms!

Thrilled that the last bit of my PhD work (and my original PhD project) finally found its way to the light: doi.org/10.1523/ENEURO.0065-25.2025 For them lovers of dentate gyrus. We quantify the excitatory and inhibitory responses of granule cells to distinct inputs from the medial perforant path.

In Vivo Analysis of Medial Perforant Path-Evoked Excitation and Inhibition in Dentate Granule Cells

Across brain regions and species, the dynamics and balance of excitation and inhibition critically determine neuronal firing. The hippocampal dentate gyrus is a brain area thought to be strongly regul...

doi.org

Still at SfN on the last day? During the morning session on the 19th, 8:00AM - 12:00PM, come check out our posters from the Moser, Zong, and Gonzalo Cogno groups in row QQ ('Grid cells and spatially modulated cells'). Ephys, imaging, remapping, development, sweeps and more! 🧠 Detailed thread below 👇

QQ2: Where are the grid cells and if so, how many? We find that grid cells form a discrete "hot spot" segregated from other functional cell types in the superficial layers of MEC and PaS. @martipof.bsky.social

Our new paper out now in Science explores how neural activity in the lateral entorhinal cortex (LEC) *drifts* over time - and *jumps* at key boundaries - to help organize events in memory. 🔗 www.science.org/doi/10.1126/... Here's a quick summary of what we found 🧵👇

Event structure sculpts neural population dynamics in the lateral entorhinal cortex

Our experience of the world is a continuous stream of events that must be segmented and organized at multiple timescales. The neural mechanisms underlying this process remain unknown. In this work, we...

science.org

Edvard I Moser@edvardmoser.bsky.social · last yr.

Your brain doesn’t just passively track time ⏳ - it structures it. In @Science.org we show that activity in 🧠 memory circuits (LEC) drifts constantly, but makes sharp jumps at key moments, segmenting life into meaningful events. (1/2) 👉 www.science.org/doi/10.1126/...