Sanne Massaar
@massaarsanne.bsky.social
PhD Candidate Hematology @ErasmusMC | Aging, DNA damage & Clonal outgrowth in blood 🧬🦴🩸
Great talk by @dpastoors.bsky.social , what a nice way to finish up #EHA2025 🤩 It's a wrap!
Dorien Pastoors@dpastoors.bsky.social · last yr.Thanks for the opportunity to present our work at the last day of #EHA2025 🤩 on MECOM as a repressor of CEBPA - also see our recent preprint: www.biorxiv.org/content/10.1... and I very much hope you can stay tuned for the final version soon-ish) #erasmusmcblood #hemesky
Spotted fellow #erasmusmcblood PhD candidate @shordijk.bsky.social at the #EHA wall of fame for her Mobility grant 🤩🤩 Congratulations !! @clotterdam.bsky.social
Congratulations Dorien, amazing achievement!! And love the cover 🤩
Dorien Pastoors@dpastoors.bsky.social · last yr.SUPER excited to share that I got my PhD thesis - thanks to a special delivery from @massaarsanne.bsky.social to Milan!! On the 26th of June, I will defend my thesis at 15:30 CET. You can follow online at eur.cloud.panopto.eu/Panopto/Page... #hemesky
SUPER excited to share that I got my PhD thesis - thanks to a special delivery from @massaarsanne.bsky.social to Milan!! On the 26th of June, I will defend my thesis at 15:30 CET. You can follow online at eur.cloud.panopto.eu/Panopto/Page... #hemesky
🚨New Blood Advances issue out now featuring: Inside Blood Advances VWF-ADAMTS13 imbalance bridges infections to stroke Predicting risk in Hodgkin lymphoma for research and clinical practice buff.ly/kKROS3q #thrombosisandhemostasis #lymphoidneoplasia
Really enjoyed the meeting too and was very happy to be awarded the presentation prize 🤩!! Extra festive touch added by @bloodadvances.bsky.social which published @massaarsanne.bsky.social 's article on this project DURING her talk 👏 @oncodeinstitute.bsky.social #oncode #kwf #hemesky
Sanne Massaar@massaarsanne.bsky.social · 2y agoEnjoyed last week's KWF Dutch Cancer Biology Meeting in the forests 🌳 of Lunteren where I got the opportunity to present on DNMT3A double mutant AML. @dpastoors.bsky.social gave nice talk on p300&CBP regulating enhancer activity in AML which was awarded with the Best Presentation Award! 🤩🥳 #Hemesky
Enjoyed last week's KWF Dutch Cancer Biology Meeting in the forests 🌳 of Lunteren where I got the opportunity to present on DNMT3A double mutant AML. @dpastoors.bsky.social gave nice talk on p300&CBP regulating enhancer activity in AML which was awarded with the Best Presentation Award! 🤩🥳 #Hemesky
Wooo - check the cover image of the current issue of Blood Advances by @massaarsanne.bsky.social & Emma Boertjes et al!!! Congratulations - methylation damage repair is impaired by double mutations in DNMT3A in AML
Sanne Massaar@massaarsanne.bsky.social · 2y agoFinally out! 🤩🎆 In this work we describe DNMT3A double mutant AML as an unique subtype with a poor prognosis and high levels of methylation damage. 👇 ashpublications.org/bloodadvance...
Finally out! 🤩🎆 In this work we describe DNMT3A double mutant AML as an unique subtype with a poor prognosis and high levels of methylation damage. 👇 ashpublications.org/bloodadvance...
Check it out!! New insights from our department on the role of MECOM and CEBPA in AML 👇👇👇
Dorien Pastoors@dpastoors.bsky.social · 2y agoExcited to share our preprint on #HemeSky: "MECOM is a master repressor of myeloid differentiation through dose control of CEBPA in acute myeloid leukemia"! @delwelruud.bsky.social and co-authors! www.biorxiv.org/content/10.1... [1/15]
Congratulations!! Fundamental insights into how mutations in DNMT3A can impair DNA damage repair 👀⬇️ 😎
Sanne Massaar@massaarsanne.bsky.social · 2y agoAlthough still in 'First Edition' style, I am happy to finally share our latest article on DNMT3A double mutant AML. Hope to be able to share the way-easier-to-read print version of the paper soon! (1/2) #hemesky ashpublications.org/bloodadvance...
Although still in 'First Edition' style, I am happy to finally share our latest article on DNMT3A double mutant AML. Hope to be able to share the way-easier-to-read print version of the paper soon! (1/2) #hemesky ashpublications.org/bloodadvance...
Double mutant DNMT3A AML: a unique subtype experiencing increased DNA damage and poor prognosis
Key Points. 1. Wildtype DNMT3A enhances TDG-mediated repair, whereas mutant DNMT3A impairs this process.2. Double mutant DNMT3A AML exhibits increased DNA
ashpublications.org
check out Mechanisms of deMethylation by Massaar et al!!! (@tvantienhoven.bsky.social i need you for better puns but the poster session is tonight)
Sanne Massaar@massaarsanne.bsky.social · 2y agoInterested in how DNMT3A mutations affect the DNA demethylation pathways in AML? Come find me at poster 2718 tonight! #hemesky #ASH24
Woohoo!! latest bluesky addition from rotterdam is fellow Delwel lab PhD student @jengelberts.bsky.social 🥳 and now we FINALLY have enough people for our own starter pack go.bsky.app/N8zjL6y 😁 #HemeSky
In the Hematology department of the EMC, we are big fans of Mate, a high-caffeine iced tea. But which brand tastes best? The only way to know was to try them all. Mio Mio ginger flavor wins! 🫚🧪
The scene is completed by the heavily loaded shelf with very old lab notebooks for this extra lab office atmosphere 😍 #academicsky Credits for most of the memes to: @thestrugglings4.bsky.social
Sanne Massaar@massaarsanne.bsky.social · 2y agoAbout a year ago @dpastoors.bsky.social and I started to fill up the empty wall in our office by adding a 'meme of the week' on every Monday morning. With the Christmas break coming up soon, here's this week's addition for you :)
About a year ago @dpastoors.bsky.social and I started to fill up the empty wall in our office by adding a 'meme of the week' on every Monday morning. With the Christmas break coming up soon, here's this week's addition for you :)
We couldn't find a starter pack for PhDs/PostDocs in life sciences so my colleague @dpastoors.bsky.social created one. There must be way more 'very' early career scientist out here, so feel free to send a message if you want to join! :) #PhD #Science #LifeScience #BiomedicalScience
Dorien Pastoors@dpastoors.bsky.social · 2y agoI am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack go.bsky.app/Jq8YaQM - if you would like to be removed/added please let me know
