Tim Triche, Jr.🔰

@timtriche.bsky.social

Executive panhandler, trichelab.vai.org Posts may contain trace quantities of blood🩸, chromatin 🧬 & stats 🧮 https://scholar.google.com/citations?user=AOoIO74AAAAJ Views expressed are my own (but for the right price they can be yours!)

In 2023, @nature.com published 'Papers and patents are becoming less disruptive over time', receiving world-wide media attention. Our Matters Arising, published after a 32 month delay (more on that soon), shows that the reported decline can largely be attributed to dataset artefacts. 🧵

The average CD_5 index per year for Web of Science. The original Park et al. decline (top curve) becomes essentially flat (bottom curve) when removing papers with CD_5=1. Those papers largely correspond to dataset artefacts.

🎯 Goodhart’s law: if you make a list of variants the target, people will get really good at calling those variants. But those variants are not a genome! As a result, we’ve been stuck trying to read genomes under the lamppost of short reads [4/15]

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Not every open-source project wants more contributors right now, and that's fine. Four shapes maintainers run — walled castle, clique, university, hippie commune — and your `CONTRIBUTING.md` is saying the quiet part out loud. No wrong answer, just an honest one. blog.stdlib.io/do-you-want-...

Do you WANT contributors?

Four ways to run an open-source project—castle, clique, university, commune—and which one you're really running.

blog.stdlib.io

Hmm, is there a way to soft-release a print of a paper for public review, Jay? Like an economics working paper. Some sort of a pre-print mechanism, if you will. 🤔 PubMed could index these, with a clear “NOT PEER REVIEWED” indication. What do you think @richardsever.bsky.social ? Madness, I guess

Jeremy Berg@jeremymberg.bsky.social · 4mo ago

(4) The CDC report on COVID vaccine efficacy He said that there were clear methodological flaws and the moderator (also an economist) agreed. If that is the case, then he should have issued a clear statement to that effort with timeline for generating a more methodologically sound paper. 24/30

Your written protocols and lab notebooks are a love letter to your future self (whether it’s you or a future lab member). Please be kind. Here are some critical things I have frequently noticed missing: (feel free to add yours in thread 🧵)