Another fishy #FluorescenceFriday. Even a simple DAPI (blue-yellow) and actin (red) staining can decorate the zebrafish one-day-old embryo spectacularly! 🐟
Matyas Bubna-Litic
@matyasbl.bsky.social
Interested in mechanobiology, morphogenesis, organisers and synthetic embryo models. Research Fellow at Mongera lab UCL, PhD in Mayor and Charras labs
We are excited to announce the results of the YEN 2026 Image Competition! Thanks to all who submitted an entry. This year amazing work has been shared with us complementing our perspectives talks on art+science. We congratulate the winners of the YEN and public votes! #yen2026 #yenimagecompetition
Happy #FluorescenceFriday! Eye of a zebrafish embryo🐟
🌟 Meet the #SDB2026 Social Media Workforce!🔬 Matyas Bubna-Litic @matyasbl.bsky.social is a Postdoc in Mongera lab at University College London (see a 🔬? it’s probably him 😉). He studies how mechanics and signaling interact during tissue elongation using synthetic embryo models 🧫
Check out the YEN Image Competition. The spectacular image on the YEN 2026 poster was the winner of last year's competition!
The YEN 2026 Image Competition is open for submissions! Enter by sending us an original image you made in the field of developmental biology. Winners will be decided by public voting. Top 10 images will be featured in future YEN materials! Submit your image here: docs.google.com/forms/d/e/1F...
The YEN 2026 Image Competition is open for submissions! Enter by sending us an original image you made in the field of developmental biology. Winners will be decided by public voting. Top 10 images will be featured in future YEN materials! Submit your image here: docs.google.com/forms/d/e/1F...
✨ A developmental biology classic! Somitogenesis of a chick embryo 🐣 is lighting up in this fluorescent HCR staining. The notochord (Chordin 🟡) and somites (PAX7 💎) are labelled. 🔬 📸 credit: Tatiane Kanno #FluorescenceFriday #devbio
The time to sign up is now!
YEN 2026 registration is now live! Join us for the 2026 YEN conference on the 15th of June at the Francis Crick Institute, London, UK. Sign up now to attend and submit your poster/abstract: forms.gle/2HQEmZgEi4hP... Abstract submission deadline is 15 May. Stay tuned for more information!
JCS snapshot - Tracking coordinated cellular dynamics in time-lapse microscopy with ARCOS.px @macdobry.bsky.social presents the key findings from their recent JCS paper with @bgraedel.bsky.social and colleagues @olivierpertz.bsky.social. journals.biologists.com/jcs/article/...
Great visual guide for how to make interpretable plots in R.
Here is a thread showcasing my GitHub repositories: 1) Friends Don't Let Friends Make Bad Graphs. An opinionated essay on good and bad graphs. My popular one by a long shot with 6.4k stars and 248 forks. github.com/cxli233/Frie...
Excited to share our new review in @dev-journal.bsky.social on tissue phase transitions during development! @karengrace12.bsky.social @nicolettapetridou.bsky.social 🔗 doi.org/10.1242/dev....
Tissue phase transitions in development: more than just mechanics
Summary: Tissue material phase transitions are classically thought to regulate tissue deformability. This Review emphasises their unexpected roles in directly influencing growth and patterning signall...
doi.org
Job alert! 📣 I’m looking for a research assistant to join my new team @idrm.ox.ac.uk Were using #zebrafish to understand gene-environment interactions that shape the heart 🫀generate natural diversity 🐸🐭 and contribute to congenital defects ❤️🩹 Full info below, and please share! 🫶🏻 bit.ly/467TO0M
Excited to share Alison's @alisonkickuth.bsky.social paper from the lab out in @nature.com this week! We uncovered how a mechanical ratchet mechanism drives cytokinesis in early #zebrafish embryos. Read more in this thread 🧵 and at www.nature.com/articles/s41... 🤩 @poldresden.bsky.social @mpi-cbg.de
My group will investigate the stochastic morphodynamics of living systems at the interface of biophysical modelling and computational biology. I will announce positions for PhD students and postdocs in the coming months! Feel free to DM me if you are interested!
We're in love with this cover image! 🧡 Part II of our Special Collection celebrating the Centennial of the Discovery of The Organiser is here. This issue focuses on the work presented at the Centennial Symposium at the University of Freiburg in September 2024: www.sciencedirect.com/journal/cell...
#Mastodon, the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets, is finally heading for publication (well, let's see). To #cite or not to cite shall no longer be the question 🙃, because the #preprint. Software is available in every #Fiji near you. www.biorxiv.org/content/10.6...
Pleased to say that Jonas Hartmann (bs-less) and I have finally released DySTrack (“diss track”) - Dynamic Sample Tracking. It’s a Python-based, modular tool that brings smart microscopy to everyday imaging on commercial systems. Preprint: www.biorxiv.org/content/10.6... [1/6]
🌈 Rainbow neurons on the move!🧠 MultiColor FlpOut of L3 optic lobe neurons projecting into the medulla neuropil. 📸 Image by Isabel Holguera. #FluorescenceFriday #DevBio
Searching for physical principles of morphogenesis In this #OpenAccess Spotlight, Nikolas Claussen, Fridtjof Brauns and @streichan.bsky.social highlight the ‘physics of development’, focusing on the interplay between quantitative experiments and mathematical theory doi.org/10.1242/dev....
Happy (and spooky) #FluorescenceFriday Switching from frogs (which are underrated btw) to zebrafish has really made me appreciate transparent tissues! 🐟 28 hpf, ⚪ nuclei, 🔴 F-actin
📣Our project, “Mechanometabolic Control of Vertebrate Limb Elongation,” has been funded by Wellcome! Over the next 8 years, we’ll collaborate with @manningresearch.bsky.social and Nathalie Agar’s group to understand the mechanics of ECM-rich mesenchymal tissues! Funded positions available!🎉
1/12 A very special moment for me! 🎉 My first paper as corresponding author—a @jcb.org Perspective on how contact-based decision-making in collective cell migration can itself encode blueprints for complex patterns and shapes. rupress.org/jcb/article/... #cellbio #devbio #science 🧵for details
Pretty cool
🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x
Our new paper is out in Dev Biol! 🎉 🐸🧬 We show #miR-196a directs #neural crest fate in #Xenopus by repressing immature neural #ectoderm — evidence #miRNAs can potentially drive, not just fine-tune, early patterning 👉 Read more here: doi.org/10.1016/j.yd... @devbiol.bsky.social @biouea.bsky.social
Mouse (Mus musculus) 🐭 is the powerhouse of mammalian genetics, essential for studying embryogenesis, organ development and gene function using transgenic technologies. 📸 Image by Zhong Hua also featured on the cover of Developmental Biology textbook (11th edition) #ModelMonday
Thank you for sharing! I'd like to highlight the concept of embryonic 'actuation' where a mechanical state change is caused by cells acting on each other through mechanics and/or biochemical signals but importantly not mediated by fate transitions.
Bubna-Litic, M., & Mayor, R. (2025). Beyond mechanosensing: How cells sense and shape their physical environment during development. Current opinion in cell biology, 94, 102514. #EpithelialMechanicsReview buff.ly/Ea2ZoFg
Got stunning fluorescence microscopy images? 🌈🔬 SDB wants to feature YOUR work for #FluorescenceFriday! We highlight images from SDB members with a short description and the image creators 📸. Fill out the form to be featured: docs.google.com/forms/d/e/1F...
✨If Monet studied mouse ovaries 🎨 Stromal cells 💜 Follicular cells 🔵 and Fatty Cells 🟡. Together, they reveal the cellular architecture and functional zones of the ovary 🔬 Image provided by @shmimberly.bsky.social 🧪 #FluorescenceFriday #ReproductiveBiology
I'm going to be advertising for a few positions in my group in the next couple of months for a big project on synthetic microbial communities. I would love to hear from you if you are interested and I'd also appreciate if everyone could share this far and wide!
✨Not a rainbow trout… a rainbow zebrafish 🌈 🐟 The expression of 10 different genes simultaneously including Hox genes along the body axis, somites, brain regions, skeletal muscle, and heart 🔬Image by Alice Sherrard, Gabby Jerz & Nipam Patel 🧪 #FluorescenceFriday