Interested in using #Drosophila genetics & advanced imaging combined with modeling to study inter-organ transport and epithelial dynamics? We’re hiring a #PhD student @uni-muenster.de, based at the Multiscale Imaging Center and @sfb1348.bsky.social Graduate School. Apply here tinyurl.com/ypx74a5d
Sebastian Streichan
@streichan.bsky.social
Excited about animal and synthetic morphogenesis, light-sheet microscopy, and quantitative biology
Sad to be saying goodbye to Drosophila, but excited to get this work out on bioRxiv! If you are interested in the interplay of tissue flows and cool ways to mess them up, this read is for you :) Thanks to colleagues and co-authors! www.biorxiv.org/content/10.6...
This epic paper, which has been a heroic 10 year journey for the lead author, Ricardo Barrientos, is finally out in Cell today! Many thanks to all co-authors, especially Billie Meadowcroft and Andela Saric for their beautiful MD simulations www.cell.com/cell/fulltex...
Basement membrane turnover controls cell shape
Basement membranes are scaffolds of proteins, like collagen, that give organs shape. During development, basement membranes must adapt to the growing organ. We infer how fast the basement membrane ada...
cell.com
Better late than never! Last month, we posted our preprint on single-cell RNA sequencing of the #zebrafish sox17 lineage — a collaboration among several labs including us, @stefanmaterna.bsky.social and @thelovelylab.bsky.social. A few key takeaways below: 1/3 www.biorxiv.org/content/10.6...
Transcriptional divergence of the zebrafish sox17 lineage begins during gastrulation
The endoderm is specified at the onset of gastrulation and subsequently undergoes extensive migration before forming an epithelial sheet that gives rise to multiple organs, including the gut and respi...
biorxiv.org
It's not often single author primary research papers are published in our field & it's even rarer when the author is a Nobel Prize winner Check out the new work by Eric Wieschaus in @dev-journal.bsky.social Flattening maternal gradients in Drosophila embryo journals.biologists.com/dev/article/...
Maternal patterning in early Drosophila embryos: how much information can single maternal gradients supply?
Highlighted Article: Comparison of the patterning capacity of Drosophila embryos that have only one of the three maternal gradients known to control anterior posterior patterning.
journals.biologists.com
Very happy to have this work finally published! How do embryos sculpt their shape? We map the contractile & adhesive forces shaping early C. elegans embryos. With K. Yamamoto @ittoku04.bsky.social G. Charras' lab @gcharras.bsky.social & my team @turlierlab.bsky.social shorturl.at/xv7G5 1/6
New Toettchlab paper alert! Harrison Oatman just published his beautiful work combining software design for "smart" microscopy+optogenetics and some really beautiful work understanding EGFR-driven collective cell migration. www.cell.com/cell-systems...
Our paper on nonlocal decoding is now out in @physrevlett.aps.org! See below for a thread about the preprint 🧵 👉 journals.aps.org/prl/abstract...
Nonlocal Decoding of Positional and Correlational Information during Development
In many developmental systems, cells differentiate into a tissue by reading out morphogen concentration fields, a process fundamentally limited by noise. How much can the precision of this process be ...
journals.aps.org
How can cells use information from neighboring cells to improve the spatial precision of morphogen patterns? 🤔 We show that cells can gain positional information by "talking" to their neighbors - how much depends critically on spatial correlations of the patterns. buff.ly/w56OUJT
@vdeneke.bsky.social and @ditalialab.bsky.social review how the spatiotemporal coordination of cellular functions across large distances is controlled by chemical waves. rupress.org/jcb/article/... 📕 Part of "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...
Michaud, @andrewgoryachev.bsky.social, von Dassow, @xenresearchcenter.bsky.social et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, & RGA-3/4 rupress.org/jcb/article/... 📕 In "Collective Behaviors and Self-Organization in Cells" rupress.org/jcb/collecti...
📣 One week left to register for #HumanDev26. We have teamed up with the @wellcometrust.bsky.social -funded consortium Human Developmental Biology Initiative (HDBI) to co-organise our 2026 Journal Meeting. Register by 24 July 2026. biologists.com/meetings/dev....
✨For this #FluorescenceFriday we are highlighting 10 amazing images of development from the Young Embryologist Network 2026 Image Competition! Follow the hashtag #yenimagecompetition for full details. 📷🔬
Happy #FluorescenceFriday! 🔥🧪🔬 A blaze of neural crest cells migrates through a developing quail embryo on one of embryonic development's most epic journeys. Beautifully captured by @vanderspuy.bsky.social 👩🔬🐣 #Devbio
Congratulations to Elaine Kushkowski whose very cool fate map paper came out today doi.org/10.1002/dvdy...
Zebrafish ventral gastrula fate map reveals neural crest progenitor domain
Background Fate maps relate progenitor cell positions to later fates and locations of their progeny, revealing early embryonic organization. Previous zebrafish fate maps identified the origin of ger.....
doi.org
Dachsous-Fat signaling shapes the Drosophila wing through mechanical forces #Drosophila
Dachsous-Fat signaling shapes the Drosophila wing through mechanical forces #Drosophila
PubMed link
pubmed.ncbi.nlm.nih.gov
I'm looking for a postgraduate intern to join my group at @humantechnopole.bsky.social, modelling how pili dynamics drive bacterial motility and aggregation. Finishing a master's in physics, computational biology, or a similar field? Get in touch: careers.humantechnopole.it/job/Internsh...
Internship - Pönisch Lab
Internship - Pönisch Lab
careers.humantechnopole.it
Remarkably, some very recent experimental results are consistent with this. In this preprint from last month, @jamesbriscoe.bsky.social and coauthors observed and modelled a landscape tilt based on the occupancy by the floor plate precursors ! www.biorxiv.org/content/10.6...
Minimal essential requirements for neural tube self-organisation
The reliable generation of diverse cell types in precise proportions is essential for the formation of functional tissues during embryonic development. Three-dimensional organoid models derived from p...
biorxiv.org
New paper 🧵 What if the "landscape" that guides cell differentiation isn't fixed, but is sculpted, in real time, by the very cells moving through it? We call this a 'sandscape' : grains of sand that carve dunes as they move, while the dunes' shape simultaneously steers where the grains go next.
Two days left to apply for a PhD position in our group, see below!
🚨Job Alert: PhD in Theoretical Biophysics 🚨 we are looking for a PhD student to join our group at Uni Münster to work on models of multi-layered active materials @uni-muenster.de More details here: stellen.uni-muenster.de/jobposting/6... Please share and contact me if interested!
Reach out if you have questions about JCS! The journal has a long history of publishing outstanding science and supporting the research community.
Working on stem cell biology? Our expert Academic Editor, Aryeh Warmflash (@warmflashlab.bsky.social), handles articles on this topic so send your article our way. It's FREE to publish in JCS and we're not-for-profit. Find out more: journals.biologists.com/jcs/pages/re... #stemcells #ISSCR2026
Harry Kane and Ronaldo proudly say that they met with Trump and played golf. Meanwhile, Erling Haaland: “No innocent children deserve to die💔” This is why Go Norway and Go Haaland. ❤️
Hot of the press- great collaboration with our friends @lmescu.bsky.social and F. Casares @cabd-upo-csic.bsky.social - building the insect eye is a feat of engineering! @uclnews.bsky.social @lmcb-ucl.bsky.social @ucl.ac.uk
New research from @fpichaud.bsky.social and University of Seville researchers found that developing fruit fly retinas behave like metamaterials, folding from flat cellular patterns into precise 3D structures. www.ucl.ac.uk/life-science... #UCLLifeSciences #Biomaterials #Metamaterials
I am so excited to announce that the Weber Lab will be opening in the Department of Anatomy, Physiology, & Cell Biology @ucdavisvetmed.bsky.social @ucdavis.bsky.social. We will be investigating the development and evolution of vertebra size, shape, and function. And yes, the jerboas are coming with!
New paper from the lab! We show that laminin α5 and two integrin receptors (α3, α6) team up to guide a group of cells moving together inside a living embryo (doi.org/10.1242/dev....) Congrats Anna & Nicola. Thanks to @chaitanyadingare.bsky.social and all authors, and to @dev-journal.bsky.social.
doi.org
After a quite long process, we are happy to share the last version of our article describing unexpected results regarding the coupling between local cell death and proliferation (heroic revision effort from @ralitzastaneva.bsky.social ) urldefense.com/v3/__https:/...
A global response contributes to tissue size robustness upon local induction of apoptosis
Tissue resilience requires tight coupling between cell proliferation, growth, and death.1,2,3,4It is assumed to be based on compensatory proliferation…
urldefense.com
It is out 😍 check it out!! Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning. @cschwayer.bsky.social @silviabarbiero.bsky.social @davidbrueckner.bsky.social @ehannezo.bsky.social www.cell.com/cell/fulltex...
Multiscale integration of tissue and chromatin context converts cell heterogeneity into stable intestinal patterning
During regeneration, tissues must translate transient cellular variability into stable spatial organization. Tissue architecture generates a density-dependent window of heterogeneity in the mechanosen...
cell.com
So proud of @sydsat.bsky.social, the lab’s first graduate student, for leading this work! Special thanks to the Searle Scholars Program and the Royalty Research Fund for making it possible. Check out the preprint here: www.biorxiv.org/content/10.6...
Early immune cell development precedes gastrulation in annual killifish
During embryogenesis, cell types arise in a predictable order because developmental regulators act sequentially. But how evolutionary changes in morphogenesis reshape the signaling environments that a...
biorxiv.org
Don't use slop. Someone's trying to make money out of you and your colleagues and your friends. Do yourself a favor and read 100% human-crated content in @prelights.bsky.social Upload preprints. Read preprints. Cite preprints. Fuck AI 🧪
Homepage - preLights
Welcome to preLights, the preprint highlights service run by the biological community and supported by The Company of Biologists. Here, a team of scientists regularly review, highlight and comment on ...
prelights.biologists.com
I'm looking for a new PhD student in Biomedical Engineering at NUS! Apply to join my team in Singapore, studying the dynamics and mechanics of collective cell organization in animal epithelial tissues. Send me your CV and a cover letter explaining your motivations via PM or email by July 22!