Our latest paper on building models of cell fate decisions -with David Rand, Marine Fontaine & @joadelas.bsky.social- combines developmental biology, dynamical systems theory and bioinformatics. I wrote a short piece to summarise it & explain ideas behind the approach briscoelab.org/blog-quantif...

Quantifying Waddington's Landscape | Briscoe Lab

I have written before about how two conceptual frameworks have shaped our thinking about cell fate, Waddington's epigenetic landscape and Davidson's gene...

briscoelab.org

The Brantley Lab is hiring a Research Technician/Lab Manager! Looking for someone with a strong foundation in molecular biology, a team player, and excited about basic science. If you know someone who would be a great fit, please share! spartantalent.uncg.edu/postings/35995

Research Lab Technician

The Brantley Lab is seeking a Research Technician who is passionate about basic science and being a reliable, collaborative member of an academic research team. Research in the Brantley Lab uses quant...

spartantalent.uncg.edu

There is still time to apply for the EMBL International PhD Programme! 📢 Don’t miss this opportunity to receive dedicated mentoring while doing interdisciplinary research. Research groups across EMBL are recruiting now! bit.ly/4x9Edss

I am absolutely thrilled to share that my K99/R00 has officially been funded by NIGMS! 🥳 Huge thanks to @ali-shariati.bsky.social and my peers in the lab, all my incredible mentors, and the MCD and BME community at UCSC. So excited for this next chapter! 🧬✨

1/23 I have fantastic news! I am truly honored to have been awarded an Emmy Noether-Grant by @dfg.de @uni-muenster.de Since most of you are not from Germany, I will use the following posts to explain what this Program is, who Emmy Noether was and what my group in Münster will be doing. #cellbio

How does a growing leaf stay flat? 🍃 Our new paper in @plosbiology.org shows that maintaining leaf flatness requires growth-rate coordination across the width of the leaf blade—not just between the top and bottom surfaces. journals.plos.org/plosbiology/...

I am very happy to share our new preprint on #Drosophila muscles. @tiaramuld.bsky.social discovered flies have a tremendous ability to remodel their muscles after massive damage. www.biorxiv.org/content/10.6...

Evidence of complete myofibril remodeling after severe damage in adult Drosophila.

Muscle function depends on the ability of myofibrils to withstand and repair mechanical damage, yet how adult muscles remodel damaged myofibrils remains poorly understood. Here, we establish a Drosoph...

biorxiv.org

www.nature.com/articles/s41...

CFM: confinement force microscopy—a dynamic, precise and stable microconfiner for traction force microscopy in spatial confinement - Nature Methods

CFM enables tunable cell confinement for measuring traction forces exerted by single cells and cell aggregates in tissue-mimicking microenvironments.

nature.com

Excited to share Will Anderson's publication describing his optogenetic FGF/ERK activator transgenic #zebrafish! Will demonstrated spatially localized FGF/ERK activation with 1 min light exposure at 1 dpf 👀 journals.biologists.com/bio/article/...

Happy #FluorescenceFriday! ✨ It's the glue that holds us together, but it looks like a pair of angel wings to me. 👼 This beautiful meshwork of extracellular matrix surrounds the developing tissues of a quail embryo, helping guide cells as they build the body. 📷 @wangjianxiong.bsky.social 🔬

The growth of #plant leaves is highly dynamic and should be coordinated, but how is #leaf flatness preserved? @roederlab.bsky.social &co show that global coordination of growth across the leaf blade is required to maintain flatness in #Arabidopsis @plosbiology.org 🧪 buff.ly/QUMxOcF

Absolutely ecstatic to share that WE GOT THE COVER!!! 🥹🎉 Seeing this on NCB's cover feels surreal. So much time, science, and teamwork went into this project, and I couldn’t be more excited to see it celebrated like this. A very, very happy day for this really really old and grown embryo 🐭🧫💥

Kate Cavanaugh@katecavanaugh.bsky.social · 4w ago

🧵 What if one reason fertility declines with age isn’t just genetic-but mechanical? Thrilled to share our new paper in @NatureCellBio : Elevated contractility drives implantation failure in mouse embryos from aged females… here’s what we found 👇 www.nature.com/articles/s41... 1/11

🌱 Our new paper about growth-derived mechanical conflicts in gynoecium and fruit morphogenesis is now out @currentbiology.bsky.social 🎉Congrats to Binghan Wang and all authors. 📄https://www.cell.com/current-biology/fulltext/S0960-9822(26)01086-9 @irbv.bsky.social @umontreal-en.bsky.social

We are looking for a postdoctoral fellow to join the team @ubcmicroimmuno.bsky.social @science.ubc.ca to study TB pathogenesis and host-directed therapy! Please help disseminate amongst your network. ubc.wd10.myworkdayjobs.com/ubcfacultyjo...

Postdoctoral Research Fellow - Host-Pathogen Interactions & Host-Directed Therapeutics

Academic Job Category Faculty Non Bargaining Job Title Postdoctoral Research Fellow - Host-Pathogen Interactions & Host-Directed Therapeutics Department Research I Sun I Department of Microbiology...

ubc.wd10.myworkdayjobs.com

The first Danionella paper from the lab. Danionella cerebrum is transparent, so you can see all of the internal organs. But what sensory information are the organs sending to the brain? In our new preprint, Emily Bayer wanted to find out. 1/4 www.biorxiv.org/content/10.6...

Very happy to share my postdoc paper is out now in @natcellbio.nature.com titled "Tissue flow acts as a guidance cue for immune cell polarization and directional migration". If you love imaging and immune cells, this is for you! #microscopymonday www.nature.com/articles/s41... A 🧵: 1/n

“Candidates using cutting-edge technologies including cryoelectron microscopy or tomography, mass spectrometry, light microscopy, &/or other technologies to advance mechanistic understanding of fundamental problems in molecular, cellular, developmental, or neuronal biology encouraged to apply.”

Sonya Neal@neal-lab.bsky.social · 2w ago

Another wonderful opportunity where UCSD School of Biological Sciences is hiring! We’re looking for an outstanding colleague to join our vibrant scientific community. Come do exciting science with us in beautiful San Diego! apol-recruit.ucsd.edu/JPF04607 Please share widely!

An interview with Alex Hughes Read our interview with Alex Hughes @hugheslabpenn.bsky.social, a Guest Editor for our special issue #DevSIextracellular, discussing the importance of the extracellular environment and the challenges it poses to classical experimental design. doi.org/10.1242/dev....

An(other) interview with Rashmi Priya Read our second interview with @rashmi-priya.bsky.social, a Guest Editor for our special issue #DevSIextracellular, discussing the importance of interdisciplinary research in #DevBio and her experience curating the special issue. doi.org/10.1242/dev....

Come be my colleague! Montreal is a great place to live and work! Tenure Track position at @mcgill.ca in quantitative cell biology with a research program to address fundamental questions in biology. @futurepislack.bsky.social mcgill.wd3.myworkdayjobs.com/McGill_Caree...

Assistant Professor in Quantitative Cell Biology - Department of Biology

Please refer to the How to Apply for a Job (for External Candidates) job aid for instructions on how to apply. If you are an active McGill employee (ie: currently in an active contract or position at ...

mcgill.wd3.myworkdayjobs.com

This was a particularly special #morpho26 course with this amazing group of scientists (aka team M&Ms)! Thanks to course organizers @roederlab.bsky.social + @streichan.bsky.social, as well as @kitp-ucsb.bsky.social for providing a fun + creative environment to tackle quantitative bio questions 💭

The last version of our EpiCure tool is now out in @dev-journal.bsky.social, a user friendly Napari plugin for epithelial segmentation curation. A bit thanks to @gaellel.bsky.social for carrying all along this joint department effort (check the details below). Feel free to use it and expand it !

Gaëlle Letort@gaellel.bsky.social · 3w ago

The final version of the paper presenting our tool EpiCure is now online: journals.biologists.com/dev/article/... !! Thanks again to all collaborators in this project

Come be my colleague!! 🎉 We’re hiring an Assistant Professor in Developmental Biology at UCSD! If you’re doing exciting work in development or regeneration, come join us!! Please spread the word and apply! apol-recruit.ucsd.edu/JPF04591

Assistant Professor of Developmental Biology

University of California, San Diego is hiring. Apply now!

apol-recruit.ucsd.edu

Do wild-caught embryos develop in the same way as embryos cultured in the lab? This summer, Beke and Mette visited Luis at IMEV in Villefranche-sur-Mer, France, to start exploring this question in the marine annelid Platynereis dumerilii. #Platynereis #annelid #Flamingo #lightsheet #cell-lineage

New preprint! Motility-induced phase separation (MIPS) goes quantum! Great numerical work by Laurin Brunner, Reyhaneh Khasseh, and Markus Heyl to show MIPS in active hard-core bosons. Personally, excited about my first paper with ℏ≠0! arxiv.org/abs/2608.25649

Happy #FluorescenceFriday! 🔥 Neural crest cells are bringing the heat again! These migrating cells weave through the developing quail embryo, leaving beautiful patterns in their wake. 😍🧪🔬 📷 @siewzhuan.bsky.social 🔬

A developmental biologist's guide to mechanics, just out in Development! In which we learn about the three pillars of any mechanical model: forces, mechanical properties, and boundary conditions. @pflenne.bsky.social @alessandrochppr.bsky.social @caojialing1002.bsky.social @dev-journal.bsky.social

A developmental biologist's guide to mechanics

Summary: A guide to mechanics in development: unlock how forces, material properties and geometry shape the forms of life.

journals.biologists.com

MS2 in zebrafish @cp-cellsystems.bsky.social! Eck, Moretti and Schlomann, in collaboration with our friends in the of @loicaroyer.bsky.social and Oates labs, discovered that smooth protein oscillations in the segmentation clock are the result of transcriptional pulses: tinyurl.com/hwbf525m

📢 Paper alert 📢 Now out in New Journal of Physics @ioppublishing.bsky.social: our first passage time analysis of a general batch arrival-degradation model doi.org/10.1088/1367... which models e.g. the time-asymmetric bursty dynamics of vesicle-mediated signaling at neurological synapses.