Sebastian Streichan

@streichan.bsky.social

Excited about animal and synthetic morphogenesis, light-sheet microscopy, and quantitative biology

🚨 FULLY FUNDED #DevBio PHD PROJECT 🚨 The Cardiac Positioning System – how do heart progenitors find their way? Discover how migrating cardiac progenitors navigate from primitive streak to heart field. 🧪🔬🐣❤️ With Prof Andrea Münsterberg and myself in Norwich UK. tinyurl.com/2np3k9x7 Please RP 🙏

Our work is finally out! How do organs get the right shape and size on time? Using the zebrafish inner ear canal, we show that a mechanical feedback loop between the ECM and Yap1 drives timely tissue growth, and a built-in termination system shuts it down once morphogenesis is done.

A self-limiting mechanotransduction feedback loop ensures robust organ formation - Nature Communications

Developing tissues must acquire the correct shape. This study shows that mechanical feedback between the extracellular matrix and Yap sustains timely tissue growth, while Adgrg6 terminates the feedbac...

nature.com

Our latest paper on building models of cell fate decisions -with David Rand, Marine Fontaine & @joadelas.bsky.social- combines developmental biology, dynamical systems theory and bioinformatics. I wrote a short piece to summarise it & explain ideas behind the approach briscoelab.org/blog-quantif...

Quantifying Waddington's Landscape | Briscoe Lab

I have written before about how two conceptual frameworks have shaped our thinking about cell fate, Waddington's epigenetic landscape and Davidson's gene...

briscoelab.org

The Brantley Lab is hiring a Research Technician/Lab Manager! Looking for someone with a strong foundation in molecular biology, a team player, and excited about basic science. If you know someone who would be a great fit, please share! spartantalent.uncg.edu/postings/35995

Research Lab Technician

The Brantley Lab is seeking a Research Technician who is passionate about basic science and being a reliable, collaborative member of an academic research team. Research in the Brantley Lab uses quant...

spartantalent.uncg.edu