In our new preprint, Réza Shahidi, Alexandra Kerbl and Karel Mocaer give an exquisitely detailed manual on serial sectioning for electron microscopy. "Volume Electron Microscopy: Tips & Tricks on Micromanipulator-Assisted Serial Sectioning for Array […] [Original post on biologists.social]
Max Telford
@maxjtelford.bsky.social
Zoologist and evolutionary biologist. Interested in animal phylogeny. At UCL. Author of 'The Tree of Life: Solving Science's Greatest Puzzle'
Thrilled to post thread re: new single-cell lineage of mouse embryo reconstructed w/ DNA Typewriter. One animal, zygote to late organogenesis (E13.5). Tree has 1,340,794 transcriptionally profiled, annotated tips (cells), 1,142,588 dated internal nodes, rooted at zygote 1/n
If you are interested in nervous system evolution you may want to read our review with Kei Jokura on nerve nets: "Revisiting nerve nets: functional organization and evolutionary implication" https://link.springer.com/article/10.1038/s44318-026-00879-w […] [Original post on biologists.social]
McDermott et al. (2026-07, Proceedings of the Royal Society B: Biological Sciences) 「動物における対称性の進化に対する形態系統学的アプローチ」 A morphological phylogenetic approach to the evolution of symmetry in animals doi.org/10.1098/rspb... うおおおおおおお!!!!!
22 years ago today, Francis Crick died. You can read about his life, his brilliance and his failures in my biography, available in hardback in the UK and USA (and as an audiobook and ebook) and soon in a chonky UK paperback.
Thoroughly enjoyed this. Lots of science, and it prompted me to read some of Crick's original writing. He had that incredible insight, like Turing, into the implications of his work and others'. Plus a fun puzzle trying to work out who some of his secret lovers were, with the aid of Google.
22 years ago today, Francis Crick died. You can read about his life, his brilliance and his failures in my biography, available in hardback in the UK and USA (and as an audiobook and ebook) and soon in a chonky UK paperback.
🔬 Meet Kevin Grüner, DC in the ZooCELL team at IGFL! Kevin completed his BSc in Biology and MSc in Zoology at the Uni. of Innsbruck, where he also worked at the EM facility and tutored different courses. He is now a DC in ZooCELL, investigating limb regeneration. 🧵 Read on to get to know Kevin.
🔬 Meet Mathilde Paris, PI and co-leader of the ZooCELL team at IGFL! In this thread, Mathilde shares what first drew her to EvoDevo, the questions that drive her research, and what she enjoys most about mentoring the next generation of scientists. 🧵👇 #EvoDevo #genomics #regeneration #MSCA #IGFL
Super excited that our paper led by @sandinmm.eurosky.social in PNAS is out! We show that crown-group eukaryotes were already taxonomically and ecologically diverse throughout the Mesoproterozoic, revealing complex communities well before the Neoproterozoic radiation. www.pnas.org/doi/10.1073/...
Environmental phylogenetics supports a steady diversification of crown eukaryotes starting from the mid-Proterozoic | PNAS
Molecular clock and preservation of early microfossil assemblages suggest that eukaryotes were present and already diverse more than ~1600 million ...
pnas.org
The paperback of CRICK is back from the printers! Out in 6 weeks. £14.99. Has the colour plates and fewer misteaks!
Fabulous to see my book Rulebreakers and Ghost Runners out in the wild on social media! #SportsHistory #WomensHistory #Skystorians
Did you know that until April 1975 women in the UK were banned from all races longer than four miles? In the 1960s, women started to break the rules and 'crash' men's races. Rulebreakers and Ghost Runners by @runyoung50.bsky.social tells their incredible stories. Out 13th August.
Please re-post to your networks :)
Today only - don't miss out! My e-book (Up - A Scientist's Guide to the Magic Above Us) is available for 99p from Amazon. Aimed at Radio 4 listeners - adult readers with an interest in the world around us but not necessarily with any science background. Tell your parents! amzn.eu/d/053vIKR9
For anyone else gutted @nedboulting.bsky.social and co. are no longer on tv for Tour de France follow this link…. neverstraysfar.com
Never Strays Far | Cycling Podcast
Hosted by Ned Boulting, David Millar and Pete Kennaugh. The three talk about lots of things, although they never stray far from the core issue, bike racing. Expect guests from the racing world and som...
neverstraysfar.com
Oh bloody hell I’d forgotten. And no @nedboulting.bsky.social. Life is a little worse. Enshitification??
Those of you who want to watch the Tour de France but don't want to spend a fortune on the subscription, you have two options: use a VPN tuned to France, and watch on france.tv (in French obvs) or go to the iPlayer and look in the channels for SC4 and watch extracts in Welsh.
Uk in second place. Politicians should be asked what the optimal number of citizens in prison should be (correct answer is surely zero) and what they’re doing to achieve that.
A grim reminder this 4th of July: The US has the highest incarceration rate of any independent democracy on Earth, making it a leader in mass incarceration. Far too many people are locked up in the “land of the free.”
HELP? Trying to get original, untrimmed alignments from this paper. Have looked very hard. Anyone able to help?? Philippe et al. Multigene analyses of bilaterian animals corroborate the monophyly of Ecdysozoa, Lophotrochozoa, and Protostomia Mol Biol Evol. 2005 May;22(5):1246-53.
I gave a talk about my book The Tree of Life at a very hot Linnean Society last Thursday. This is now available to view on YouTube. www.youtube.com/watch?v=SzT2...
The Tree of Life (A User’s Manual) | Max Telford
YouTube video by Linnean Society
youtube.com
🔬 Meet Ina Arnone, ZooCELL PI at @szndohrn.bsky.social In this Q&A, she shares how she discovered EvoDevo, the big questions driving their research and her passion for mentoring the next generation of scientists. Follow the thread to learn more. 👇 #MSCA #ZooCELL #EvoDevo @arnonelab.bsky.social
Buckenmeyer et al. (2026-04, Genome Biology and Evolution) (open access) Patterns of conservation and loss of Hox genes in xenacoelomorph lineage since divergence from last common bilaterian ancestor academic.oup.com/gbe/advance-...
1/ Deep-time phylogenetics is hard: overly simplistic substitution models can mislead tree estimation at the billion year timescale. Our new preprint introduces GTRspmix, a protein modeling framework designed to more realistically model site-to-site heterogeneity in amino acid replacement. 🧵
Yeah what we need is some 'riz. Enough of these reasonably competent bureau-techno-crats. www.theguardian.com/politics/202...
Keir Starmer to step down as prime minister two years after historic election victory
Labour leader bows to mounting pressure after Andy Burnham’s success against Reform UK in Makerfield
theguardian.com
We are advertising a 3-year Evolution Education Trust funded #PhD studentship at @ugiatucl.bsky.social UCL to investigate the genomic history of infectious diseases preserved within historical pathology collections. Details: www.findaphd.com/phds/project.... #findaphd #EET
Unlocking the Genomic History of Pathogens Through Pathology Archives at University College London on FindAPhD.com
PhD Project - Unlocking the Genomic History of Pathogens Through Pathology Archives at University College London, listed on FindAPhD.com
findaphd.com
Less than a week until I talk about my book 'The Tree of Life' @linneansociety.bsky.social. 25th June, 6pm, tickets available here: members.linnean.org/events/69f21...
The Tree of Life (A User’s Manual)
Max Telford takes us inside one of science’s greatest quests: reconstructing the web of relationships between all our planet’s species.
eventbrite.co.uk
I will be talking about The Tree of Life at the Linnean Society on 25th June. If you are interested you can find out a little more and sign up for a ticket at the link below. Hope to see some of you there! members.linnean.org/events/69f21...
The first single-cell three-dimensional lamprey brain atlas reveals that the vertebrate common ancestor already had a highly regionalized brain, and subsequent neuronal specialization likely drove vertebrate brain diversification. Learn more this week in Science: https://scim.ag/4whLqXp
SAVE THE EXTRAORDINARY BHL!! www.theguardian.com/environment/...
A bonanza for fans of the natural world: the digital library sharing 64m pages of scientific knowledge with everyone
The Biodiversity Heritage Library is an invaluable online archive of historic texts on species living and lost supplied by the world’s leading museums and universities. Now its future is in doubt
theguardian.com
It's very difficult to work out the relationships between spiral cleaving phyla. With interesting implications for their origins and the interpretation of Cambrian fossils. Work by @anaserrasilva.bsky.social. Supported by @leverhulme.ac.uk.
Now officially out in @elife.bsky.social! See how @maxjtelford.bsky.social and myself approached resolving spiralian relationships. doi.org/10.7554/eLif...
“Maximilian has errors. Edit and fix to continue.” Sigh.