@meravcohenlab.bsky.social
A new #ScienceImmunology study highlights an approach called Effero-seq, which shows that efferocytosis of tumor cells in mouse models of melanoma can induce protumoral functions in macrophages. https://scim.ag/4uRkpte
Efferocytosis induces proangiogenic function and chromatin remodeling in tumor-associated macrophages
Effero-seq reveals efferocytosis induction of macrophage chromatin remodeling and proangiogenic function in the TME.
scim.ag
We are thrilled to share the newest publication from our lab! In this work, @RoiBalaban & @OriMoskowitz investigated the effect of #efferocytosis on #macrophage state and function in the #TME. www.science.org/doi/10.1126/...
Efferocytosis induces proangiogenic function and chromatin remodeling in tumor-associated macrophages
Effero-seq reveals efferocytosis induction of macrophage chromatin remodeling and proangiogenic function in the TME.
science.org
We are thrilled to be selected for the EACR top 10 cancer research publications !!! magazine.eacr.org/highlights-i...
Highlights in Cancer Research: December 2025 - The Cancer Researcher
The EACR's 'Highlights in Cancer Research' is a regular summary of the most interesting and impactful recent papers in cancer research.
magazine.eacr.org
Thank you@deadoc80.bsky.social for your thoughtful commentary on @cp-trendscancer.bsky.social! This builds upon our data and shows the potential for novel therapeutic startegies targeting the TAM-TAN-tumor cell signaling niche we found. www.sciencedirect.com/science/arti...
A macrophage-neutrophil program drives mammary carcinogenesis
The molecular and cellular pathways through which breast cancer evades immunosurveillance remain poorly understood. Recent data from Camargo et al. de…
sciencedirect.com
Thank you @naturecancer.bsky.social for selecting our study to be featured on the cover of the monthly issue! www.nature.com/natcancer/vo... @sandracamargog.bsky.social @orimoskowitz.bsky.social @meravcohen.bsky.social #Neutrophils #PIC-seq #BreastCancer #TME
By integrating single-cell RNA and physically interacting cell sequencing analysis, @meravcohen.bsky.social and colleagues report that neutrophils are enriched in physical crosstalk with breast tumor cells, promoting cancer aggressiveness. ⬇️ www.nature.com/articles/s43...
Neutrophils physically interact with tumor cells to form a signaling niche promoting breast cancer aggressiveness - Nature Cancer
By integrating single-cell RNA and physically interacting cell sequencing analysis, here Cohen and colleagues report that neutrophils are enriched in physical crosstalk with breast tumor cells, promot...
nature.com
Thank you @soehnleinlab.bsky.social for the beautiful ‘News and Views’ on our manuscript! @naturecancer.bsky.social @meravcohenlab.bsky.social www.nature.com/articles/s43...
Neutrophils take their PICk to promote breast cancer - Nature Cancer
Tumor-infiltrating neutrophils can have either pro-tumoral potential or anti-tumoral potential. Physical contact between heterogeneous neutrophils and tumor cells in the tumor microenvironment is now ...
nature.com
We are beyond excited to share the first publication of our lab! We highlight the role of #neutrophils in shaping a more aggressive #TME through physical interactions with #breastcancer cells. The work was led by the talented @sandracamargog.bsky.social & @orimoskowitz.bsky.social 🧵