A prostaglandin prevents macrophages from clearing toxic neutrophils in aging organs, according to new Science research in mice. Learn more in a new #SciencePerspective: https://scim.ag/4fdUVBc

Tidying up aging organs

A prostaglandin prevents macrophages from clearing toxic neutrophils in aging organs

scim.ag

Thrilled to share our new paper in @sciimmunology.bsky.social www.science.org/doi/10.1126/...

PhD position offer! We are looking for a motivated PhD candidate to join my lab at the University of Münster.

A prostaglandin prevents macrophages from clearing toxic neutrophils in aging organs @science.org www.science.org/doi/10.1126/... www.science.org/doi/10.1126/...

Thank you @soehnleinlab.bsky.social for the beautiful ‘News and Views’ on our manuscript! @naturecancer.bsky.social @meravcohenlab.bsky.social www.nature.com/articles/s43...

Neutrophils take their PICk to promote breast cancer - Nature Cancer

Tumor-infiltrating neutrophils can have either pro-tumoral potential or anti-tumoral potential. Physical contact between heterogeneous neutrophils and tumor cells in the tumor microenvironment is now ...

nature.com

Grateful to the huge team & collabs @soehnleinlab.bsky.social @udalovalab.bsky.social, LaiGuan Ng, L. Walsh, and many more. This was a marathon of single-cell biology, spatial transcriptomics, cytokine screens, genetic models, and computational modeling, all to chart the neutrophil universe.

Our new paper is out in @natcardiovascres.nature.com 🥳 Neutrophils are released from the bone marrow in a graded continuum of maturity under stress. We show its deepest point predicts survival after STEMI, and can be captured with a routine blood count parameter. www.nature.com/articles/s44...

Depth of neutrophil mobilization stratifies survival in ST-elevation myocardial infarction - Nature Cardiovascular Research

Richter et al. show that the mobilization of neutrophil progenitors assessed from routine blood tests can predict 30-day mortality in patients following ST-elevation myocardial infarction and enable r...

nature.com

New study: A simple routine blood value can spot high-risk heart attack patients right at hospital admission. Immature immune cells predicted 30day mortality better than established biomarkers. @natcardiovascres.nature.com @soehnleinlab.bsky.social @lmu-klinikum.bsky.social @isas-leibniz.bsky.social

Immature immune cells predict chances of survival following a heart attack

In the event of a severe heart attack, immature immune cells are released into the bloodstream from the bone marrow. A research team led by the University of Münster has demonstrated that the maturity...

uni-muenster.de

The quest for interventions ro slow down #Aging never gets old. Here a CV perspective @naturecvr.bsky.social www.nature.com/articles/s41...

Roadmap for alleviating the manifestations of ageing in the cardiovascular system - Nature Reviews Cardiology

In this Roadmap, Stellos and colleagues discuss the mechanisms of cardiovascular system ageing and how the ageing of blood, vessels and heart relates to the decline in organ function, and highlight po...

nature.com

β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus @natimmunol.bsky.social www.nature.com/articles/s41...

#InterferonPower! Khan Tran Divanghai &co show @natimmunol.bsky.social that systemic fungal b-glucan administration potentates granulopoieis via type I IFNs (not IL1!) driving IL10-producing neutrophils that protect against lung influenza A virus infection increasing immune tolerance, not resistance

β-Glucan reprograms neutrophils to promote disease tolerance against influenza A virus - Nature Immunology

Divangahi and colleagues report that β-glucan pretreatment before influenza A virus challenge can increase survival by inducing long-term reprogramming of neutrophils, promoting disease tolerance irre...

nature.com

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