The BioStimulaTOR Lab

@meyerchrisscience.bsky.social

Interested in N metabolism, the plant TOR kinase pathway and biostimulation

Our fantastic PhD student Samuel Laurent received the award for the best talk by a young scientist at the Plant Energy Management meeting in Montpellier (PEM26)🤗. So proud and so glad !! By the way it was really a great meeting with an open minded and nice community! Thanks to the organizers !!🙏

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Dans un monde sans faucheur on aurait probablement eu des colza transgéniques : Résistant aux meligetes Résistant au phoma Résistant au sclerotinia A teneur élevée en lipides spécifiques Plus efficace pour la nutrition azotée Avec un égrenage réduit Au coté des variétés classiques Qui le sait ?

Beware of misinterpretations in -omics analyses! (IPS2-SPS)

Beware of misinterpretations in -omics analyses! (IPS2-SPS)

A very large proportion of false specific DEG when using few replicates and Venn Diagramms.   Omics analyses represent a crucial step in the search for condition-specific events and often rely on Venn diagrams. In stress experiments for example, the presence of differentially expressed genes exclusively under combined stress conditions is frequently interpreted as evidence of non-additive effects: the effect of combined stresses would differ from the sum of the effects of individual stresses.   In an article published in Nature Plants (Ferraro et al. 2026), to test the relevance of this line of reasoning, the Gnet team and the OGE team with several collaborators at IPS2, and the POPS, PAPPSO and Phenoscope platforms, generated a transcriptomic and proteomic dataset under a control condition, two single stresses, and the combination of both stresses, with 22 biological replicates.   Analysing this dataset, Ferraro et al. demonstrate that identifying specific responses using Venn diagrams generates many false positives. This is explained by the low statistical power inherent in most omics studies that use  too few replicates (typically around 3).   Ferraro et al. 2026 thus highlights the need to interpret any claims about the specificity of such omics datasets with caution, and advocate for improvements in statistical modeling to avoid misleading biological interpretations.   Contact : guillem.rigaill@universite-paris-saclay.fr   https://www.nature.com/articles/s41477-026-02303-x     Figure: Evolution of the number of true and false specific DEGs as a function of the number of replicates. (Left) Venn diagram of DEGs under single and combined stress conditions; (Right) Number of genes correctly identified as specific (blue), falsely identified as specific (red), and falsely identified as differentially expressed (gray) as a function of the number of replicates.

nature.com

Over the past year, @biologyopen.bsky.social has expanded its Fast & Fair initiative to accelerate peer review. The results are impressive - take a look at their latest preprint to find out more: www.biorxiv.org/content/10.6...

biorxiv.org

Daniel Gorelick@danielgorelick.bsky.social · 2mo ago

Paying peer reviewers works. Expanded Fast & Fair experiment @biologyopen.bsky.social: • 5.5 vs 37.7 working days to decision with reviews • ~3 vs ~9 reviewer invitations per manuscript • no reduction in editor-assessed review quality • similar acceptance rates www.biorxiv.org/content/10.6...

Scatter plot showing that Fast & Fair peer review reached first decision with reviews much faster than conventional peer review: mean 5.5 versus 37.7 working days. Most Fast & Fair manuscripts met the 7-working-day target, while conventional manuscripts were slower and more variable, up to 116 working days.

Waou… Il y a des jours où je n’ai plus les mots. À 17h, déjà 149 records de chaleur ont été battus en France, y compris dans des stations installées au XIXᵉ siècle. En FEVRIER, s'il vous plait (quel délire !), on approche les 30°C au pied des Pyrénées, plus de 25°C sur la moitié nord. 1/5

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Houlalala le suspens est insoutenable : ce reportage va t il être anti OGM ? quand on itw - Une chercheuse qui a témoigné au procès des faucheurs volontaires en leur faveur - une ancienne ministre farouchement antiOGM - une ONG anti ogm - le Criigen (au secours) - un député PS anti ogm Suspens

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Yann Duroc@durocyann.bsky.social · 8mo ago

Je découvre un projet de documentaire d’etudiantes de master sur les NGT …je me dis chouette, des jeunes qui s’intéressent au sujet et apparemment leur démarche est vraiment honnête, cool Et patatras, une vidéo Instagram qui dit que l’UE a redéfini le mot naturel avec une enfilade de perle anti ogm

Our preprint is finally out 🌿 “𝒑𝒑𝑮𝒑𝒑 𝒑𝒓𝒐𝒎𝒐𝒕𝒆𝒔 𝒉𝒊𝒈𝒉-𝒍𝒊𝒈𝒉𝒕 𝒕𝒐𝒍𝒆𝒓𝒂𝒏𝒄𝒆 𝒊𝒏 𝑨𝒓𝒂𝒃𝒊𝒅𝒐𝒑𝒔𝒊𝒔” Its been a journey- first spotted by Matteo Sugliani over ten years ago, carried forward by Shanna Romand, and brought to the finish line with help from many collaborators. #PlantScience tinyurl.com/wpf3bp25

Guanosine tetraphosphate (ppGpp) signalling promotes high-light tolerance in Arabidopsis thaliana.

Guanosine tetraphosphate (ppGpp) is a hyperphosphorylated nucleotide originally discovered in prokaryotes and found in the chloroplasts of plants and algae. In plants, ppGpp signalling plays a role as...

biorxiv.org

So glad to share a part of the PhD work of our student Justine Broutin that is now published in Physiologia plantarum! We explored the mechanisms of biostimulation by protein hydrolysates in plants using Arabidopsis and multi level phenotyping. onlinelibrary.wiley.com/share/3P7572...

Multi‐Level Investigation in Arabidopsis of the Growth‐Stimulating Effects of a Protein Hydrolysate Biostimulant

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onlinelibrary.wiley.com