Mike Fainzilber

@mfainzilber.bsky.social

Molecular neuroscience, cell biology, aikido and haiku, not necessarily in that order. https://www.weizmann.ac.il/Biomolecular_Sciences/Fainzilber/

So how is zooid identity determined? Using transcriptomics and open chromatin profiling, we uncover that many transcription factors are zooid-specific, largely coinciding with cognate TF motif enrichments on those same polyps. We propose complex coloniality relied on co-option of ancestral TFs. 4/

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By sequencing the genome and through comparative genomics, we found that it doesn't have significant gene family expansions in developmental / information processing genes (e.g. Transcription Factors, signalling pathways). However its large genome (>3Gb) is ~75% transposons. 3/

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The man'o war (Physalia utriculus) is a siphonophore, and as such a colony of polyps. But unlike other colonial animals like corals 🪸, each polyp has a distinct role & morphology. How does a unique genome encode such complexity? Also, it has a nasty sting, can we better understand its venom? 2/

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I have a brief article on the life and work of #senryu poet Shinko Tokizane in the latest issue of Prune Juice, which came out today. Check it out at the link below!

Prune Juice Journal@prunejuicejournal.bsky.social · 5d ago

Issue no. forty-nine is live, featuring cover art from one of this issue’s poets, Debbie Strange! Thank you to everyone who contributed. www.prunejuicesenryu.com Mark your calendars for the next submission window: October 1st – 31st. #senryu #micropoetry #writingcommunity #haiku #poetryjournal

Years ago, I reviewed a paper that had interesting data but was not put well together at all. Badly organized figures, convoluted text. I was getting annoyed and then saw the asterisk in the (short) author list. The first author had written their first ever ms after their PI had suddenly died 🥺.

If you don't like a paper, it is obviously totally fine to point out the issues. But please do NOT make egregious and unpleasant comments about the first author's qualifications. A first author who is usually a trainee. Beyond inappropriate and unprofessional.