My time lapse of the Gironde #fire near Bordeaux, viewed on Friday afternoon from about 20 km distance. One minute compressed into 5 seconds. #GlobalHeating

#SundayMorning

Yammy...

Every lab needs its own coffee ☕ place

Take a look at this new paper in @science.org Reversible suppression of autophagy in a mouse model reveals neuronal resilience | Science www.science.org/doi/10.1126/...

Reversible suppression of autophagy in a mouse model reveals neuronal resilience

Impairments in intracellular quality-control mechanisms, including autophagy, affect neuronal integrity and function. Despite numerous studies aimed at slowing neuronal deterioration, it remains uncle...

science.org

After 2 months of hard work by @shanshuo.bsky.social with huge support by @manuelgonzalezfuen.bsky.social,help by @nico-slz.bsky.social & a bit myself (😅) we did "finalise" our paper & are finally "𝘶𝘯𝘥𝘦𝘳 𝘳𝘦𝘷𝘪𝘦𝘸" 🤞 Here is the last version of our paper: www.biorxiv.org/content/10.6... #openscience

Autophagy acts as a spatial organizer of cell-type-specific plant immunity

Effective plant immunity requires precise spatial coordination of immune responses across cell-types to restrict pathogens while preventing tissue damage, yet the intracellular pathways that organize ...

biorxiv.org

Şuayb Üstün@suaybuestuen.bsky.social · 2mo ago

2) 🔬We show that EDS1 is degraded by autophagy during Pst infection - most likely in the mesophyll 🌱🦠 Our model: autophagy recycles EDS1 during infection. Without this turnover, EDS1 accumulates (explaining elevated SA in atg5?!) but EDS1-dependent HR fails. 🔄💥 Ready to submit 🤞

Our paper is out !!! NADPH oxidases and aquaporins within membrane nanodomains form a functional unit for ROS signaling. Great work by arthur-poitout.bsky.social and amazing collaborator jbfiche.bsky.social, Jose Ugalde, A Meyer yvonjaillais.bsky.social! www.pnas.org/doi/10.1073/pnas.2529740123

1/7 New preprint: we found that Chlamydomonas carries a giant and unexpectedly elaborate chloroplast RNA polymerase with 12 previously unknown subunits, overturning the idea that the complexity of this organellar enzyme emerged during plant terrestrialization! www.biorxiv.org/content/10.6...

The structure of a 2-MDa chloroplast RNA polymerase reveals unexpected evolutionary complexity

Transcription in chloroplasts depends on the Plastid-Encoded RNA polymerase (PEP), a bacterial-derived enzyme whose catalytic core remains encoded by the highly reduced genome inherited from the cyano...

biorxiv.org

It was pure pleasure listening to these #plantscience giants, one after the other, in an even organised by @volcaniinstitute.bsky.social and @hebrewuniversity.bsky.social.

Volcani Institute@volcaniinstitute.bsky.social · 2mo ago

Congratulations to the Wolf Prize Laureates! Prof. Caroline Dean, Prof. Venkatesan Sundaresan, Prof. Elliot M. Meyerowitz, Prof. Brian J.Staskawicz, Prof. Jonathan D.G Jones, and Prof. Jeff Dangl.

The Thermo Fisher situation keeps getting worse. We've now collected 450+ problematic images presented as verification data in TF's antibody catalog. This includes: 🖌️ Dozens more images with duplications or painting 🖨️ Hundreds of blots that all share the same background (behold slideshow below)

So proud to see this story finally out!🎉 We added new data since our previous preprint—transgenic barley plants with an engineered immune receptor that fights off two fungal pathogens at once. Short 🧵 and link to the original preprint thread on X👇 www.science.org/doi/10.1126/...

Molecular mimicry of a pathogen virulence target by a plant immune receptor

Plants and animals respond to pathogen attack by mounting innate immune responses that require intracellular nucleotide-binding leucine-rich repeat (NLR) proteins. These immune receptors detect pathog...

science.org

We just published our new paper about an active Helitron transposon in wheat 🌾🧬 We found that it can be mobilised by heat stress when DNA methylation is reduced. We document its full lifecycle: RNA -> circular DNA -> integration www.nature.com/articles/s41... #TEsky

An active Helitron transposon family in wheat - Nature Plants

Helitrons are a recently identified category of transposons. This study reveals that heat stress combined with reduced DNA methylation can mobilize a Helitron family in wheat. Its mobilization is gene...

nature.com

Fascination of Plants celebration is here! 🌱 Check out all 8 posters of our exhibition through this website. fopd-utrecht.nl/en/exhibitio... 🌱 Can plant research also have other purposes? See what UU Plant researchers honestly think! #plantscience

Our work is out now! (www.science.org/doi/10.1126/...). We discover a selective autophagy pathway that protects plants from the mess caused by RNA viruses. Intrigued? Follow the spaghetti trail for a summary of our findings🧵-->

Selective autophagy fine-tunes plant immunity to promote cell survival during viral infection

RNA viruses co-opt host endomembranes to form replication complexes, often triggering cellular stress and immune responses. Here, we show that Arabidopsis thaliana activates selective autophagy to res...

science.org

One of my role models in academia, combining brilliance with humility-Noboru Mizushima, & I like him even more now ❤️ “If I was given the chance to repeat my research career, I think I would choose to study plant biology.” journals.biologists.com/jcs/article/...

Interview with Noboru Mizushima – President of the Japan Society for Cell Biology

Noboru Mizushima is Professor of Biochemistry and Molecular Biology at the University of Tokyo, Japan, where he runs a laboratory studying the mechanisms and physiological functions of autophagy and o...

journals.biologists.com

A long road with this one, with many questions still to answer, but out now in @embojournal.org! RAB-A2a, Kin12s and TIO interact to coordinate membrane-phragmoplast dynamics during cytokinesis. Big thanks to @ckirchhelle.bsky.social for letting me explore this! link.springer.com/article/10.1...

A Rab/Kinesin-12/kinase module couples vesicle delivery and phragmoplast dynamics during plant cell cytokinesis - The EMBO Journal

Cytokinesis is a key process in the development of multicellular organisms, through both formative and proliferative divisions. In land plants, successful cytokinesis requires precise targeting of Gol...

link.springer.com

Excited to share our latest piece in Trends in Plant Science! 🌱🔬 www.sciencedirect.com/science/arti... We highlight how single-cell laser ablation reveals plant development, wound responses, and root defenses. @TrendsPlantSci @KAUST_BESE @ESNematologists @umeaplantscie ncecentre.se #PlantScience

Single-cell laser ablation uncovers the blueprint of plant development

Understanding how positional information within plant tissues shapes developmental programs in real time has long remained a challenge due to technica…

sciencedirect.com

For this #FluorescenceFriday, beautiful round tonoplast memebranes engulfing chloroplasts (magenta) and a stomata (cyan) sends a kiss. Image taken by talented postdoc Hala Khamesa-Israelov. #PlantScience

The rise of polyploids during environmental upheaval: Cell www.cell.com/cell/fulltex...

The rise of polyploids during environmental upheaval

From the dating of 132 ancient whole-genome duplication events across 470 angiosperms, paleopolyploidization events cluster around pivotal periods of environmental upheaval and extinction, notably the...

cell.com

For this #FluorescenceFriday, beautiful round tonoplast memebranes engulfing chloroplasts (magenta) and a stomata (cyan) sends a kiss. Image taken by talented postdoc Hala Khamesa-Israelov. #PlantScience

Thrilled to introduce our next act 🎭 in @cp-molcell.bsky.social sciencedirect.com/science/arti... led by @glangin.bsky.social We uncover how proteotoxic stress is integrated across compartments, controlling proteasome activation ⚖️ vs photosynthesis repression 🌱 🧵(1/6) #proteostasis

🚨 Paper out now in #ScienceAdvances @science.org 🌱🦠 Pathogens don’t just target protein degradation—they also hijack host translation. "Bacteria use P-body condensates to attenuate host translation during infection" ⚖️♻️ led by @manuelgonzalezfuen.bsky.social www.science.org/doi/10.1126/...

Another paper hot off the press! We profiled protein abundance, acetylation, and phosphorylation in rice infected with Magnaporthe oryzae. Awesome work led by @pri-auler.bsky.social. It was great hosting her in my lab for a year long post-doc internship!!! onlinelibrary.wiley.com/doi/10.1111/...

🔥our latest study is now online @natcomms.nature.com we found that the salicylic acid catabolic enzymes DMR6/DLO1 are controlled by the ubiquitin system. SA modulates their turnover, revealing a regulatory circuit linking hormone metabolism to immune balance. www.nature.com/articles/s41...

Beautiful creative work and a great 🧵 Kudos to all involved in this nice work 🧪

Deepa Rajan, PhD@deeparajan.bsky.social · 3mo ago

How can a single cell learn without a brain? We explore this in my paper with @wallaceucsf.bsky.social! We discovered that single cells may learn using molecules similar to those that animal brains use to learn, like CaMKII. Cells can also propagate memory states to their progeny!

Mammalian-like steroidogenesis in plants gives rise to endocrine-mimetic cardenolides #PlantScience #SecMet From: www.science.org/doi/full/10....

Mammalian-like steroidogenesis in plants gives rise to endocrine-mimetic cardenolides

Plants carry out mammalian-like steroidogenesis that generates endocrine-mimetic cardenolides.

science.org

Congrats @sheilaroitman.bsky.social et al!

PlantEvolution 🌱🌾@plantevolution.bsky.social · 4mo ago

1/8 🔥 New preprint dropped: Dynamic co-existence of bacteriophages and their hosts 🦠 in the Arabidopsis thaliana 🌱 phyllosphere Work led by the indomitable @sheilaroitman.bsky.social‬ #plantscience #microbiome #holobiont www.biorxiv.org/content/10.6...

jobportal.ku.dk/administrati... We are soon to be headless.... So come be our new boss in lovely Copenhagen and lead a department with research interests from genes to ecosystems, and everything alive in between.

Head of Department, Department of Biology

jobportal.ku.dk

Preprint alert 🚨 (1/10) 🧵 𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺: It can promote resistance, susceptibility, or restrict cell death 🤯 So what is its actual role? We show it acts as a spatial organizer of immunity across cell types 🌱🦠 #proteostasis www.biorxiv.org/content/10.6...