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Matthew Saunders

@mjsaunder.bsky.social

Public health physician and social epidemiologist passionate about addressing inequities in health and wellbeing through practice, research, and advocacy https://www.researchgate.net/profile/Matthew-Saunders-3?ev=hdr_xprf

21 Posts44 Follower58 Folgt
Matthew Saunders@mjsaunder.bsky.social · 2w ago

Bedaquiline resistance is increasing globally and threatens to undermine efforts to end TB. In this cohort study from Uzbekistan, we describe the characteristics, treatment strategies, and long-term health outcomes of people with bedaquiline-resistant TB academic.oup.com/ofid/advance...

Characteristics, treatment strategies, and long-term health outcomes of people with bedaquiline-resistant tuberculosis in Karakalpakstan, Uzbekistan – a retrospective cohort study

AbstractBackground. Bedaquiline resistance is increasing globally, threatening effectiveness of short regimens for rifampicin/multi-drug resistant (RR/MDR)

academic.oup.com

Lara Goscé@laragosce.bsky.social · 2mo ago

Poverty is a major driver of TB.Conditional cash transfers combined with counselling improve pre-treatment loss to follow-up.In this economic analysis our modelling projections show that this intervention is cost-effective and can reduce incidence and mortality. www.sciencedirect.com/science/arti...

Cost-effectiveness of conditional cash transfers with pre- and post-test tuberculosis counselling in South Africa: a modelling analysis

Tuberculosis (TB) disproportionately affects low-income populations due to socioeconomic barriers. Conditional cash transfers (CCTs) are promising str…

sciencedirect.com

Matthew Saunders@mjsaunder.bsky.social · 2mo ago

So...what would happen to the global TB epidemic if we "eliminated" undernutrition? Our paper out now @lancetgh.bsky.social, where we combined estimates from our review (academic.oup.com/ije/article/...) with population-specific BMI distributions to find out...(www.thelancet.com/journals/lan...

Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study

Almost a quarter of global tuberculosis incidence in adults could be averted by eliminating undernutrition, approximately two-and-a-half times higher than current estimates. These findings highlight t...

thelancet.com

Finn McQuaid@cfmcquaid.bsky.social · 3mo ago

So...what would happen to the global TB epidemic if we "eliminated" undernutrition? Our paper out now @lancetgh.bsky.social, where we combined estimates from our review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(www.sciencedirect.com/science/arti...)

Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study

Current efforts to reduce global tuberculosis incidence have proved insufficient, highlighting that urgent action is needed to address underlying modi…

sciencedirect.com

Finn McQuaid@cfmcquaid.bsky.social · 9mo ago

Our framework that informed the @who.int TB & climate change policy brief out now in @lancetrespirmed.bsky.social, exploring the intersections and implications of climate change for the TB epidemic. Key message? TB should be considered a climate-sensitive disease www.thelancet.com/journals/lan...

Climate change and tuberculosis: an analytical framework

Climate change is likely to exacerbate a range of determinants that drive tuberculosis, the world's leading cause of death from a single infectious agent. However, tuberculosis is often neglected in w...

thelancet.com

The Lancet Infectious Diseases@thelancetinfdis.bsky.social · 9mo ago

New comment: Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative www.thelancet.com/journals/lan...

Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative

Undernutrition is a key driver of the global tuberculosis epidemic, increasing the risk of people developing tuberculosis disease and of poor outcomes in those who do.1 Each year, WHO publishes estima...

thelancet.com

Matthew Saunders@mjsaunder.bsky.social · 9mo ago

“Wow, I saw in the last GTB report undernutrition is much less important for TB than we previously thought” I hear you say… Well, no. We think this is an underestimate, & as much as 28% of TB could be attributable to undernutrition – see our latest comment here: www.thelancet.com/journals/lan...

Tuberculosis and undernutrition: improving estimates to reinforce the policy imperative

Undernutrition is a key driver of the global tuberculosis epidemic, increasing the risk of people developing tuberculosis disease and of poor outcomes in those who do.1 Each year, WHO publishes estima...

thelancet.com

Matthew Saunders@mjsaunder.bsky.social · 11mo ago

So...what would happen to the global TB epidemic if we hypothetically "eliminated" undernutrition? In this preprint, we combined estimates from our new review (doi.org/10.1093/ije/...) with population-specific BMI distributions to find out...(doi.org/10.1101/2025...)

Global, regional, and national estimates of tuberculosis incidence averted by eliminating undernutrition in adults: a modelling study

Background Current efforts to reduce global tuberculosis incidence have proved insufficient, highlighting that urgent action is needed to address underlying modifiable risk factors such as undernutrit...

doi.org

Matthew Saunders@mjsaunder.bsky.social · 11mo ago

Nutritional status is a key determinant of TB. In this updated systematic review and dose-response meta-analysis (43 cohorts inc > 26 million people) we redefined the relationship between body mass index (BMI) and TB. doi.org/10.1093/ije/...

Body mass index and tuberculosis risk: an updated systematic literature review and dose–response meta-analysis

AbstractBackground. The relationship between nutritional status and tuberculosis is critically important but poorly understood. We extended a 2009 review c

doi.org

Matthew Saunders@mjsaunder.bsky.social · 12mo ago

The global TB epidemic is driven by social determinants. In this case-control study in Peru, we characterised the associations between multidimensional household poverty, personal risk factors, and TB. @tb-lshtm.bsky.social idpjournal.biomedcentral.com/articles/10....

The social determinants of tuberculosis: a case-control study characterising pathways to equitable intervention in Peru - Infectious Diseases of Poverty

Background Despite being key components of global tuberculosis policy, poverty reduction and social protection interventions have been inconsistently implemented. We aimed to characterise how poverty ...

idpjournal.biomedcentral.com

The Union@theunion.org · 12mo ago

The Union's TB Undernutrition working group is hosting a webinar with Dr Matthew Saunders. 📅 21 August at 2pm CET Dr Saunders (@lshtm.bsky.social‬) will share findings from a new analysis that redefines the relationship between BMI and TB incidence. 📧 To join email membership@theunion.org.

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