Welcome Eneida Hatcher from the NIH! Her extensive experience will strengthen Switzerland's leadership in pathogen tracking and epidemic preparedness, including through flagship global project the Pathogen Data Network (PDN). @dessimoz.bsky.social @tanjastadler.bsky.social

Eneida Hatcher joins SIB as Centre for Pathogen Bioinformatics director

Genomic surveillance expert Eneida Hatcher joins SIB today as director of the Centre for Pathogen Bioinformatics. Coming from the US National Institutes of Health (NIH), she brings over a decade of ex...

sib.swiss

I want to spell this out in case the implications aren't clear: This means all public tools/webapps of GISAID data (all the ones you've been used to seeing thru the pandemic, as far as we can tell) are prohibited. The file allowed this. Cut that - cut off all tools the public & others were using.

Nextstrain@nextstrain.org · 9mo ago

On Oct 1, 2025, GISAID informed us that they had ended updates to the flat file of SARS-CoV-2 genomic sequences and associated metadata that we had used to update Nextstrain analyses since Feb 2020. GISAID's stated rationale was that their "resources are limited". 1/5

Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols. Thread 1/n

We're looking for highly motivated candidates for PhD positions in the physics of living systems. Our group uses theoretical physics to understand how cells collectively self-organize. If you're interested, get in touch & check out the Biozentrum PhD Fellowship program, deadline October 12th!

Biozentrum, University of Basel@biozentrum.unibas.ch · last yr.

Apply now for the prestigious and independent #BiozentrumPhDFellowships. Great science. Unique rotation-based selection of research group and other incentives. The summer call is open until October 12, 2025. bit.ly/4caiqqX @biozentrum.unibas.ch @unibas.ch #fellowship #PhD#Switzerland

Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...

Pasteur-Paris University International doctoral program​ (PPU)

OverviewIn 2009, the Institut Pasteur, the world leading biomedical research institute founded by Louis Pasteur in 1887, inaugurated the Pasteur Paris-University (PPU) international doctoral program i...

pasteur.fr

Institut Pasteur | 130 years of biomedical research@pasteur.fr · 11mo ago

🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry. Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, PPU-@ox.ac.uk, PPU-EID @upcite.bsky.social & more 🧬 Register now ✍️ www.pasteur.fr/en/education...

It was a great pleasure to contribute to this work by Jemma Fendley, @mmolari.bsky.social, and Boris Shraiman on pan-genomes, linkage, and recombination in phage genomes. We analyzed data collected by the fantastic SEA-PHAGES program in phagesdb.org. [1/6] www.biorxiv.org/content/10.1...

📢New job posting!📢 Are you excited by the idea of building global infrastructure to make pathogen sequencing more accessible, interpretable, and equitable? 🧑🏻‍💻🧬 My group at @swisstph.ch has an opening working with ARTIC2, @pathoplexus.org, & Loculus - read on! 1/5

Bonsai is out! Finally, we can visually explore high-dimensional data in a distortion-free way. Try it out! It works from scRNA-seq data (bonsai.unibas.ch/bonsai-scout...) up to football statistics (bonsai.unibas.ch/bonsai-scout...). 
Ever wondered why low-dimensional embeddings like t-SNE

Erik van Nimwegen@erikvannimwegen.bsky.social · last yr.

Here it is! Bonsai. Now there is really no more excuse for using t-SNE/UMAP. Bonsai not only makes cool pictures of your data. It actually rigorously preserves its structure. No tunable parameters. Incredible work by @dhdegroot.bsky.social. I'm so excited about this! www.biorxiv.org/content/10.1...

Agencies within the Trump administration have flagged hundreds of words to limit or avoid, according to a compilation of government documents. These terms appeared in government memos, in official and unofficial agency guidance and in other documents. www.nytimes.com/interactive/...

The contribution of natural transformation for the acquisition of novel genes has been notoriously difficult to quantify because it relies on recombination (which is affected by other processes). Here's a first estimate : doi.org/10.1101/2025... (for the very busy: 1-6% of gene gains) #MicroSky

Building on the UShER tree of millions of SARS-CoV-2 genomes maintained by Angie Hinrichs, Hugh Haddox and Georg Angehrn (and others in @matsen.bsky.social lab and @jbloomlab.bsky.social) have looked into how the neutral mutation rate varies along the genome: [1/N] www.biorxiv.org/content/10.1...

The mutation rate of SARS-CoV-2 is highly variable between sites and is influenced by sequence context, genomic region, and RNA structure

RNA viruses like SARS-CoV-2 have a high mutation rate, which contributes to their rapid evolution. The rate of mutations depends on the mutation type (e.g., A→C, A→G, etc.) and can vary between sites ...

biorxiv.org

Thrilled to announce that our work (w. with fantastic @neher.io and Liam Shaw) has been published on Molecular Biology and Evolution! 🎉 academic.oup.com/mbe/advance-... Are you curious about how fast the genome of E.coli evolves structurally (gains, rearrangements...) ? 🧬 A summary thread [1/N]🧵

Quantifying the evolutionary dynamics of structure and content in closely-related E. coli genomes

Abstract. Bacterial genomes primarily diversify via gain, loss, and rearrangement of genetic material in their flexible accessory genome. Yet the dynamics

academic.oup.com

It's a huge honour to have been named by Nature as "One to Watch" in 2025 for @pathoplexus.org ! 🙏 I'm proud to see Pathoplexus continuing to draw attention - but this is truly a team effort and only possible thanks to all the amazing people involved! 🙌 swisstph.ch/en/news/news... 1/2

Swiss TPH Researcher Emma Hodcroft Named by Nature as 1 of 3 People To Watch in 2025

Emma Hodcroft, group leader at Swiss TPH and assistant professor at the University of Basel, was named one of three people to watch in shaping science in 2025 by the renowned...

swisstph.ch

It's an incredible honour to have received this #OpenData prize from Swiss Academies of Arts & Sciences for @pathoplexus.org! Though not everyone in Pathoplexus could be there in person, it was a fantastic & thought-provoking event, & I'm so glad were part of it! #OpenScience #OpenSource

Pathoplexus@pathoplexus.org · 2y ago

We're incredibly honoured to be winners of the Swiss Academies of Arts & Sciences National Prize for Open Research Data 2024! 🎉🎊 "Pathoplexus ensures open access and provides a cutting-edge infrastructure for interactive and programmable data exploration" akademien-schweiz.ch/en/medien/pr... 1/2